Media contributions
1Media contributions
Title Cancer risk associated with anti-TIF1 antibodies Degree of recognition International Media name/outlet Nature Reviews Rheumatology Media type Print Country/Territory United Kingdom Date 7/01/19 Description atients with dermatomyositis are more likely to develop cancer if they are positive for anti-transcriptional intermediary factor 1 (TIF1) antibodies than if they are negative (HR 3.4 (95% CI 2.2–5.4)), according to the results of a UK study of 263 patients. During a 10-year follow-up period, cancer occurred exclusively within a 3-year window either side of diagnosis in anti-TIF1 antibody-positive patients and was most common in patients over the age of 39. Patients with anti-TIF1 antibodies also had a higher risk of ovarian cancer than those without (19% of cancers versus 2% of cancers, respectively; P < 0.05). Producer/Author Joanna Collison URL https://www.nature.com/articles/s41584-019-0164-3 Persons Hector Chinoy, Alexander Oldroyd, Janine Lamb
Research Beacons, Institutes and Platforms
- Lydia Becker Institute