THE OBSERVER: The 10 biggest science stories of 2022 – chosen by scientists

Press/Media: Expert comment

Period18 Dec 2022

Media contributions

1

Media contributions

  • TitleThe 10 biggest science stories of 2022 – chosen by scientists
    Media name/outletThe Observer
    Media typeWeb
    Country/TerritoryUnited Kingdom
    Date18/12/22
    DescriptionVaccine technology has seen an unprecedented acceleration in innovation that could soon be benefiting us in a host of ways. A vaccine works by delivering an “infection” signal (something from the germ) and an “alert” signal (to wake the immune response up). As our knowledge of immunology has increased, so too has our capacity to innovate in the vaccines that deliver those signals. Designing any new vaccine takes a long time, significant investment and a lot of eager volunteers, all of which was accelerated during the pandemic, resulting in a host of novel developments.

    The autumn Covid-19 booster shots we have just been offered are one such example – these bivalent vaccines target the original strain of Sars-CoV-2 (the virus that causes Covid-19) alongside the Omicron variant. Bivalent vaccines have advantages over the original vaccines as they both top up and broaden our immunity. But what if you could broaden your immunity further – to not just two but multiple strains of virus? So-called multivalent vaccines for Covid-19 and flu are looking very promising. Another approach we could soon see is the use of sniffable or inhalable vaccines – mucosal vaccines. These are already used in China to tackle Covid-19 and may offer long-term protection against respiratory viruses. They are also much more appealing for those of us who are needle-phobic. If these new developments deliver on their promise, then one day soon the calls for annual shots could be a thing of the past. Sheena Cruickshank

    Sheena Cruickshank is professor of biomedical sciences and public engagement at the University of Manchester
    URLhttps://www.theguardian.com/science/2022/dec/18/the-10-biggest-science-stories-of-2022-chosen-by-scientists
    PersonsSheena Cruickshank

Keywords

  • COVID-19
  • coronavirus
  • vaccines