Processed single cell RNA-seq data for manuscript "HAND1 level controls the specification of multipotent cardiac and extraembryonic progenitors from human pluripotent stem cells"

  • Matthew Birket (Creator)
  • Adam Lynch (Creator)
  • Naomi Phillips (Creator)
  • megan douglas (Creator)
  • Marta Dorgnach (Creator)
  • I-Hsuan Lin (Creator)
  • Antony Adamson (Creator)
  • Zoulfia Darieva (Creator)
  • Jessica Whittle (Creator)
  • Neil Hanley (Creator)
  • Nicoletta Bobola (Creator)

Dataset

Description

Processed single cell RNA-seq (scRNA-seq) data (10xGenomics Flex) and metadata from Lynch et al. The EMBO Journal 2025, https://doi.org/10.1038/s44318-025-00409-0, stored in Loom format. The loom file includes wild-type (WT) and HAND1-null (KO) cells ("colAttrs/condition"). Metadata also includes the day/timepoint of differentiation ("colAttrs/day"), the assigned cell type ("colAttrs/cellType") and the SCENIC regulon AUC scores for each cell ("colAttrs/regulonAUC").
Date made available10 Mar 2025
PublisherUniversity of Manchester Figshare

Keywords

  • ScRNA-seq
  • Cardiac differentiation
  • HAND1
  • SCENIC GRN Analysis

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