Quantitative LC-MS/MS proteomics of human kidney microsomes

Dataset

Description

The aim of this study was to quantify enzymes and transporters in 20 human kidney cortex fractions. Using targeted accurate mass retention time (AMRT) and global proteomic approaches, 6 UGTs, 3 CYPs, 22 transporters, 1 adhesion and 1 plasma membrane marker were quantified; Eight of these proteins were identified for the first time in the kidney. The global proteomic method identified >4000 proteins. Kidney CYP2B6, CYP3A5 and CYP4F2 showed generally low expression.
Date made available2021
PublisherPRoteomics IDEntifications Database
Date of data production30 Aug 2021

Keywords

  • Human,
  • quantitative proteomics
  • kidney,
  • LC-MS/MS,
  • microsomes,

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