Supplementary material from "Synthesis of isopropyl-substituted anthraquinones via Friedel–Crafts acylations: migration of isopropyl groups"

  • Abdel Chakiri (Creator)
  • Philip Hodge (Creator)



    Friedel–Crafts reactions of isopropyl-substituted benzenes with phthalic anhydride in the presence of aluminium trichloride, followed by cyclization of the products with strong sulfuric acid give, as expected, anthraquinones. The syntheses, however, often afford more than one anthraquinone. In some cases the isopropyl groups migrate cleanly to other ring positions: in other cases they are lost.
    Date made available8 Aug 2017


    • quinone
    • synthesis
    • rearrangements

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