Description

Fibrillin microfibrils are large supramolecular ECM assemblies which play different functional roles in different tissues. We aim to compare the ultrastructure and biological composition of fibrillin microfibrils purified from human eye, skin and cultured dermal fibroblasts. This will allow us to understand whether these their structure and compositions have evolved to suit the functions they play in different tissues.
Date made available16 Feb 2018
PublisherPRoteomics IDEntifications Database
Date of data production31 Dec 2018

Research Beacons, Institutes and Platforms

  • Lydia Becker Institute
  • Manchester Institute for Collaborative Research on Ageing

Keywords

  • Fibrillin microfibril
  • Collagen VI microfibril
  • Proteomics
  • LC-MS/MS
  • Human dermal fibroblast
  • Human ciliary body
  • Human skin
  • LTQ Orbitrap Elite
  • Shotgun Proteomics

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