Narrative
Our research has led to a step change in care, from simple inhaled therapies to more effective, simpler to use, combination dual and triple therapies. Our industrial collaborations delivered a new dual therapy, and three new triple therapies. Most recently, the first triple combination therapy to be approved in Europe for COPD. These treatments have reduced known risks of multiple single inhaler use and brought more effective treatment options to patients globally. Notably, AstraZeneca‘s dual inhaler, approved by the European Medicines Agency (EMA) and US Food and Drug Administration (FDA), is available in 25 countries. UoM research has been included in the National Institute for Health and Care Excellence (NICE) guidance evidence reviews, cited in Australian and New Zealand Clinical Guidelines and in internationally renowned Global Initiative for Chronic Obstructive Lung Disease (GOLD) Strategy documents.Impact date | 1 Aug 2013 → 31 Dec 2020 |
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Category of impact | Health and wellbeing, Economic |
Impact level | Adoption |
Research Beacons, Institutes and Platforms
- Lydia Becker Institute
Documents & Links
Related content
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Research output
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Once-Daily Single Inhaler Triple Versus Dual Therapy in Patients with COPD
Research output: Contribution to journal › Article › peer-review
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Extrafine inhaled triple therapy versus dual bronchodilator therapy in chronic obstructive pulmonary disease (TRIBUTE): a double-blind, parallel group, randomised controlled trial
Research output: Contribution to journal › Article › peer-review
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Single inhaler triple therapy versus inhaled corticosteroid plus long-acting β2-agonist therapy for chronic obstructive pulmonary disease (TRILOGY): a double-blind, parallel group, randomised controlled trial
Research output: Contribution to journal › Article › peer-review
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Efficacy and safety of aclidinium bromide/formoterol fumarate fixed-dose combinations compared with individual components and placebo in patients with COPD (ACLIFORM-COPD): a multicentre, randomised study
Research output: Contribution to journal › Article › peer-review
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Superiority of "triple" therapy with salmeterol/fluticasone propionate and tiotropium bromide versus individual components in moderate to severe COPD
Research output: Contribution to journal › Article › peer-review
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Single inhaler extrafine triple therapy versus long-acting muscarinic antagonist therapy for chronic obstructive pulmonary disease (TRINITY): a double-blind, parallel group, randomised controlled trial
Research output: Contribution to journal › Article › peer-review
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Impacts
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Development and application of inhaled therapies in airway diseases
Impact: Health impacts