Narrative
In collaboration with Manchester University NHS Foundation Trust (MFT) and industrial partner Vitalograph, we have developed the first accurate system to quantify coughing. The VitaloJAK, built with our algorithm technology has been used in 36 clinical trials to date, increasing the number of studies evaluating cough treatments. It is the only cough monitor approved for use in regulatory clinical trials in Europe and the US and has facilitated the development of the first potential treatment for refractory chronic cough (Gefapixant). Vitalograph’s CEO reports revenue of over GBP40,000,000 due to cough monitor adoption which also helped the company create 50 new jobs within UK and Ireland. In addition, it has brought over [text removed for publication] revenue into MFT from royalties, to March 2020.Impact date | 1 Aug 2013 → 31 Dec 2020 |
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Category of impact | Health and wellbeing, Economic |
Impact level | Adoption |
Research Beacons, Institutes and Platforms
- Lydia Becker Institute
Documents & Links
Related content
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Research output
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Transient receptor potential vanilloid 1 (TRPV1) antagonism in patients with refractory chronic cough: a double-blind randomized controlled trial.
Research output: Contribution to journal › Article › peer-review
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Chronic cough: How do cough reflex sensitivity and subjective assessments correlate with objective cough counts during ambulatory monitoring?
Research output: Contribution to journal › Article › peer-review
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How to quantify coughing: Correlations with quality of life in chronic cough
Research output: Contribution to journal › Article › peer-review
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P2X3 receptor antagonist (AF-219) in refractory chronic cough: a randomised, double-blind, placebo-controlled phase 2 study.
Research output: Contribution to journal › Article › peer-review
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Gefapixant in two randomised dose-escalation studies in chronic cough
Research output: Contribution to journal › Article › peer-review
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Gefapixant, a P2X3 receptor antagonist, for the treatment of refractory or unexplained chronic cough in a phase 2b randomised controlled trial
Research output: Contribution to journal › Article › peer-review