DOSY and Pure Shift NMR: from changed practice in the chemical, pharmaceutical and scientific instrument industries to a multimillion-pound new food ingredient

Impact: Economic, Technological


Pioneering research at The University of Manchester (UoM) has driven major advances in nuclear magnetic resonance (NMR) methodology, resulting in pulse sequences and analysis software that are incorporated in over 90% of modern liquid state NMR spectrometers worldwide – a USD1,000,000,000 per annum market. These advances have changed practice and capacity in industry, through the introduction of new products and processes. Diffusion-ordered spectroscopy (DOSY) is having significant economic impact: one food industry company (Givaudan) reports sales growth of >GBP100,000,000 in this REF period as a direct result of a new flavour component found using DOSY. Pure shift methods are routinely used by major companies (e.g. Syngenta), and are now a standard feature on spectrometers supplied by all major manufacturers.
Impact date1 Aug 201631 Jul 2020
Category of impactEconomic, Technological
Impact levelAdoption