Improved management of population cardiovascular risk in diabetic patients

  • Paul Durrington (Participant)
  • Michael Mackness (Participant)
  • Valentine Charlton-Menys (Participant)
  • Michael France (Participant)

Impact: Health impacts


The Collaborative Atorvastatin Diabetes Study (2004), led by researchers at the University of Manchester (UoM), established the efficacy of statin therapy in the prevention of atherosclerotic cardiovascular disease (CVD) among patients with diabetes. The research challenged the previously held view that, since CVD risk is markedly raised in people with diabetes even when blood cholesterol levels are normal, statins were unlikely to be beneficial for this group. These key findings have informed clinical guidelines governing the use of statin therapy in the UK (NICE, SIGN) and internationally (American Heart Association and the American Diabetes Association, ESC, EAS), ensuring that statins are now considered for all diabetic patients.
Impact date2014
Category of impactHealth impacts
Impact levelBenefit