Narrative
Age Related Macular Degeneration (AMD) is by far the leading cause of blindness in older people in the developed world, affecting 30% of those aged over 65, and is set to increase. The naturally-occurring carotenoids lutein (L) and zeaxanthin (Z) are located in the central retina (macula) and are collectively called the macular pigment (MP). High MP levels confer protection from AMD. Murray and colleagues have developed a new instrument, the Macular Pigment Screener (MPS), which allows regular, non-invasive monitoring of MP in ophthalmic practice. This means that, for the first time, the MPS can show the effect of intervention on the MP, providing a management strategy for AMD patients, and allowing early identification of those at risk of developing AMD. Over 750 instruments have been sold to date, with more than 1M patients in the US alone estimated to be benefiting from routine MP testing.Impact date | 2014 |
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Category of impact | Economic impacts, Health impacts, Societal impacts, Technological impacts |
Impact level | Benefit |
Documents & Links
Related content
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Research output
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Correspondence between retinal reflectometry and a flicker-based technique in the measurement of macular pigment spatial profiles
Research output: Contribution to journal › Article › peer-review
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Plasma and macular responses to lutein supplement in subjects with and without age-related maculopathy: A pilot study
Research output: Contribution to journal › Article › peer-review
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A new desktop instrument for measuring macular pigment optical density based on a novel technique for setting flicker thresholds
Research output: Contribution to journal › Article › peer-review
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Lutein supplementation over a one-year period in early AMD might have a mild beneficial effect on visual acuity: The CLEAR study
Research output: Contribution to journal › Article › peer-review
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Macular pigment optical density measurement: A novel compact instrument
Research output: Contribution to journal › Article › peer-review
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Macular pigment and risk for age-related macular degeneration in subjects from a northern European population
Research output: Contribution to journal › Article › peer-review