Successfully tackling serious fungal diseases to transform global population health

Impact: Health and wellbeing


Over a billion people worldwide are affected by serious fungal disease, resulting in over 1.5 million deaths annually. Our research led an evidence-based global advocacy programme to address lack of diagnostics and generic antifungals as well as inadequate clinical skills. Denning set up the Global Action Fund for Fungal Infections (GAFFI) in 2013 to mitigate the global impact of fungal diseases. Five antifungal drugs and eight key diagnostics are now flagged by the World Health Organization (WHO) as ‘Essential’, and GAFFI has produced estimates of fungal diseases for 65 countries. National clinical training programmes in Guatemala and Nigeria for HIV patients with life-threatening fungal infections resulted in improved clinical skills and saved lives.
Impact date1 Aug 201331 Dec 2020
Category of impactHealth and wellbeing
Impact levelAdoption

Research Beacons, Institutes and Platforms

  • Global inequalities
  • Lydia Becker Institute
  • Global Development Institute