Research output per year
Research output per year
Organisation profile
Overview
The Cancer Research UK Manchester Institute is a leading cancer research institute within The University of Manchester. It is core funded by Cancer Research UK, the largest independent cancer research organisation in the world.
The Institute's research spans the whole spectrum of cancer research, from programmes investigating the molecular and cellular basis of cancer, to those focused on translational research and the development of therapeutics. The Institute is based in the Paterson Building which is adjacent to The Christie NHS Foundation Trust.
The Institute is a partner in the CRUK Centre of Excellence for Lung Cancer and is also a key part of the Belfast-Manchester Movember Centre of Excellence for Prostate Cancer.
Find out more at the Cancer Research UK Manchester Institute website.
Related areas
For more about cancer research at Manchester, you can also explore:
- Manchester Cancer Research Centre;
- Division Cancer Sciences;
- The Faculty of Biology, Medicine and Health's cancer research domain.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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A randomised trial of a T2-composite-biomarker strategy adjusting corticosteroidtreatment in severe asthma, a post- hoc analysis by sex
RASPUK Investigators, 5 Jan 2023, In: The journal of allergy and clinical immunology. In practice.Research output: Contribution to journal › Article › peer-review
Open Access -
Assessing the communication gap between AI models and healthcare professionals: Explainability, utility and trust in AI-driven clinical decision-making
Wysocki, O., Davies, J. K., Vigo, M., Armstrong, A. C., Landers, D., Lee, R. & Freitas, A., Mar 2023, In: Artificial Intelligence. 316, 103839.Research output: Contribution to journal › Article › peer-review
Open Access -
A three-gene leukaemic stem cell signature score is robustly prognostic in chronic myelomonocytic leukaemia
Wang, Y-H., Yao, C-Y., Lin, C-C., Gurashi, K., Amaral, F. M. R., Bossenbroek, H., Jerez, A., Somervaille, T. C. P., Binder, M., Patnaik, M. M., Hou, H-A., Chou, W-C., Batta, K., Wiseman, D. H. & Tien, H-F., 1 Apr 2023, In: British Journal of Haematology. 201, 2, p. 302-307 6 p.Research output: Contribution to journal › Article › peer-review
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A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote migration of lung cancer cells
Ginn, L., Maltas, J., Baker, M. J., Chaturvedi, A., Wilson, L., Guilbert, R., Amaral, F. M. R., Priest, L., Mole, H., Blackhall, F., Diamantopoulou, Z., Somervaille, T. C. P., Hurlstone, A. & Malliri, A., 3 Oct 2023, In: Proceedings of the National Academy of Sciences. 120, 40, e2300489120.Research output: Contribution to journal › Article › peer-review
Open Access -
Autocrine activation of MAPK-signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells
Steiner, I., Flores-Tellez, T. D. N. J., Mével, R., Ali, A., Wang, P., Schofield, P., Behan, C., Forsythe, N., Ashton, G., Taylor, C., Mills, I. G., Oliveira, P., McDade, S., Zaiss, D. M., Choudhury, A., Lacaud, G. & Baena Chaparro, E., 23 Mar 2023, (Accepted/In press) In: Cell Reports.Research output: Contribution to journal › Article › peer-review
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NIHR Manchester Biomedical Research Centre
Bruce, I., Lord, G., Lennon, R., Black, G., Wedge, D., Morris, A., Hussell, T., Sharrocks, A., Stivaros, S., Buch, M., Gough, J., Kostarelos, K., Thistlethwaite, F., Kadler, K., Barton, A., Hyrich, K., Mcbeth, J., O'Neill, T., Vestbo, J., Simpson, A., Singh, S., Smith, J., Felton, T., Murray, C., Griffiths, C., Cullum, N., Rhodes, L., Warren, R., Paus, R., Dumville, J., Viros Usandizaga, A., Keavney, B., Tomaszewski, M., Allan, S., Body, R., Cartwright, E., Heagerty, A., Kalra, P., Miller, C., Rutter, M., Smith, C., Trafford, A., Evans, D., Crosbie, E., Crosbie, P., Harvie, M., Howell, S., Renehan, A., Dive, C., Blackhall, F., Landers, D., Krebs, M., Cook, N., Clarke, R., Taylor, S., Jorgensen, C., Lorigan, P., Jayson, G., Valle, J., Mccabe, M., Armstrong, A., Freitas, A., Illidge, T., Choudhury, A., Hoskin, P., West, C., Van Herk, M., Faivre-Finn, C., Bristow, R., Kirkby, K., Birtle, A., Mackay, R., Radford, J., Linton, K., Higham, C., Munro, K., Plack, C., Arden Armitage, C., Bruce, I., Moore, D., Saunders, G., Stone, M., Haddock, G., Lewis, S., Elliott, R., Green, J., Lovell, K., Morrison, A., Shaw, J., Bucci, S., Ainsworth, J., Webb, R., Newman, W., Banka, S., Clayton-Smith, J., Payne, K., Moldovan, R., Wynn, R. & Jones, S.
1/12/22 → 30/11/27
Project: Research
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Centre for Digital Trust and Society
Barrett, E., Allmendinger, R., Elliot, M., Lord, N., Cordeiro, L., Gibson, R., Papamarkou, T., Dresner, D., Buil-Gil, D., Aldridge, J., Duncan, P., Banach, R., Brown, G., Dennis, L., Fisher, M., Korovin, K., Kotselidis, C., Luján, M., Mustafa, M., Olivier, P., Reger, G., Zhang, N., Hodgkinson, G., Gulati, S., Ainsworth, J., Chen, Y., Green, B., Healey, M., Uyarra, E., Zachariadis, M., Little, C., Mackey, E., Nenadic, G., Keane, J., Shlomo, N., Laskowski, N., Jarwar, M. A., Shariati Samani, S., Smith, D., Kambites, M., Thorpe, M., Rowley, P., Flynn, S., Turner, P., Wainwright, V., Czerwinsky, A., Nini, A., Broad, R., Shute, J., Deakin, J., Taboada, P., Knight, P., Hutchings, S., Whyte, J., Tolz-Zilitinkevic, V., Pilkington, H., Guharoy, S., Nicolo, A., Reggiani, C., Garcia Oliva, J., Van Someren, A., Bon, E., Cantijoch Cunill, M., Koch, D. & Chen, Y.
11/05/21 → …
Project: Other
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MAnchester RESearch Transforming Radiation Oncology (MAESTRO) Programme as Part of CRUK RadNet.
Bristow, R., Burnet, N., Choudhury, A., Dive, C., Faivre-Finn, C., Hagan, I., Hoskin, P., Hussell, T., Illidge, T., Kirkby, K., Kostarelos, K., O'Connor, J., Peek, N., Rattray, M., Taylor, S., Thornton, D., Van Herk, M., West, C., Whetton, A., Williams, K. & Yorke, J.
1/11/19 → 31/10/24
Project: Research
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NIHR Biomedical Research Centre: Cancer Precision Medicine Theme.
Dive, C., Baena Chaparro, E., Blackhall, F., Bruce, I., Bundred, N., Carter, L., Clarke, R., Cook, N., Crosbie, P., Evans, D., Harris, J., Hawkins, R., Hussell, T., Illidge, T., Jayson, G., Jorgensen, C., Kirwan, C., Kostarelos, K., Krebs, M., Lorigan, P., Marais, R., Marshall, K., Metcalf, R., Payne, K., Radford, J., Somervaille, T., Springer, C., Taylor, S., Thistlethwaite, F., Viros Usandizaga, A. & Zelenay, S.
1/04/17 → 31/03/19
Project: Research
Impacts
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Making ECGs intuitively explainable to the public for early detection of life-threatening heart conditions (ECG-X)
Caroline Jay (Participant), Alaa Alahmadi (Participant), Markel Vigo (Participant), Alan Davies (Participant), Jennifer Royle (Participant), Leanna Goodwin (Participant), Katharine Cresswell (Participant), Zahra Arain (Participant) & Katherine Dempsey (Participant)
Impact: Technological, Health and wellbeing
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Molecular markers and drug development leading to improvements in radiotherapy.
Ian Stratford (Participant), Kaye Williams (Participant), Catharine West (Participant), Caroline Dive (Participant), Rachel Airley (Participant), Amanda Eustace (Participant) & Aoife Shannon (Participant)
Impact: Health impacts
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Online tool created to support decisions regarding hospital admissions or discharge in cancer patients presenting with symptoms of COVID-19 and the likely severity of illness
Rebecca Lee (Corresponding participant) & Caroline Dive (Participant)
Impact: Health and wellbeing
Activities
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Cancer Research UK LTD (External organisation)
Iain Hagan (Academic expert member)
1 May 2019 → 2 May 2019Activity: Membership › Membership of committee
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Conferences Jacques Monod:Mitotic and Meiotic Cell Cycle control and execution
Iain Hagan (Chair) & Katja Wassman (Co-Chair)
8 Apr 2019 → 12 Apr 2019Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc
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Cancer Research UK LTD (External organisation)
Iain Hagan (Academic expert member)
11 Mar 2019 → 12 Mar 2019Activity: Membership › Membership of committee
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The Wellcome Trust (External organisation)
Iain Hagan (Academic expert member)
15 Jan 2019 → 15 Jan 2022Activity: Membership › Membership of committee
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American Association for Cancer Research (External organisation)
Patricia Muller (Academic expert member)
24 Dec 2018 → 24 Dec 2019Activity: Membership › Membership of professional association
Datasets
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Monocarboxylate Transporter 1 (MCT1) is an independent prognostic biomarker in endometrial cancer
Latif, A. (Contributor), Chadwick, A. (Contributor), Kitson, S. (Contributor), Gregson, H. (Contributor), Sivalingam, V. (Contributor), Bolton, J. (Contributor), McVey, R. J. (Contributor), Roberts, S. (Contributor), Marshall, K. (Contributor), Williams, K. (Contributor), Stratford, I. (Contributor) & Crosbie, E. (Contributor), figshare , 28 Dec 2017
DOI: 10.6084/m9.figshare.c.3963363.v1, https://figshare.com/collections/Monocarboxylate_Transporter_1_MCT1_is_an_independent_prognostic_biomarker_in_endometrial_cancer/3963363/1
Dataset
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Investigation of cell fate decision in Schizosaccharomyces pombe by ncRNA annotation and statistical analyses
Bitton, D. (Contributor), Grallert, A. (Contributor), Scutt, P. J. (Contributor), Yates, T. (Contributor), Li, Y. (Contributor), Bradford, J. R. (Contributor), Hey, Y. (Contributor), Pepper, S. D. (Contributor), Hagan, I. (Contributor) & Miller, C. (Contributor), PANGAEA, 1 Jan 2012
DOI: 10.1594/pangaea.775713, https://doi.pangaea.de/10.1594/PANGAEA.775713
Dataset
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TuFClot Study Raw Data 04JUL2019
Castle, J. (Contributor), Kirwan, C. (Contributor) & Descamps, T. (Contributor), Mendeley Data, 11 Jul 2019
DOI: 10.17632/742ftgfg54.2, https://data.mendeley.com/datasets/742ftgfg54
Dataset
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Supplementary Material for: Sun Protection Behavior in Organ Transplant Recipients in Queensland, Australia
Iannacone, M. R. (Creator), Iannacone, M. R. (Creator), Pandeya, N. (Creator), Isbel, N. (Creator), Campbell, S. (Creator), Fawcett, J. (Creator), Soyer , H. P. (Creator), Ferguson, L. (Creator), Davis, M. (Creator), Whiteman, D. C. (Creator) & Green, A. (Creator), figshare , 2017
DOI: 10.6084/m9.figshare.5128708
Dataset
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Investigating the feasibility and acceptability of a cognitive behavioural suicide prevention therapy for people in acute psychiatric wards (the ‘INSITE’ trial): study protocol for a randomised controlled trial
Haddock, G. (Contributor), Davies, L. (Contributor), Evans, E. (Contributor), Emsley, R. (Contributor), Gooding, P. (Contributor), Heaney, L. (Contributor), Jones, S. (Contributor), Kelly, J. (Contributor), Munro, A. (Contributor), Peters, S. (Contributor), Pratt, D. (Contributor), Tarrier, N. (Contributor), Windfuhr, K. (Contributor) & Awenat, Y. (Contributor), figshare , 11 Feb 2016
DOI: 10.6084/m9.figshare.c.3600323.v1, https://figshare.com/collections/Investigating_the_feasibility_and_acceptability_of_a_cognitive_behavioural_suicide_prevention_therapy_for_people_in_acute_psychiatric_wards_the_INSITE_trial_study_protocol_for_a_randomised_controlled_trial/3600323/1
Dataset
Prizes
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ASH/EHA Translational Research Training in Haematology Fellowship 2017
Wiseman, Daniel (Recipient), Jan 2017
Prize: Fellowship awarded competitively
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Cancer Research UK Future Leaders in Cancer Research Prize
Zelenay, Santiago (Recipient), 6 Nov 2017
Prize: Prize (including medals and awards)
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CRUK Advanced Clinician Scientist Fellowship
O'Connor, James (Recipient), 1 Jun 2016
Prize: Fellowship awarded competitively
Press/Media
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MAIL ONLINE: New blood test could spare thousands of lung cancer patients from chemotherapy by spotting if tumour will spread
Caroline Dive
7/10/19
1 Media contribution
Press/Media: Research
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MANCHESTER EVENING NEWS: New Year Honours 2018
Diane Coyle, Caroline Dive, CEM Griffiths & Vikas Shah
29/12/17
1 Media contribution
Press/Media: Other
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MANCHESTER EVENING NEWS: Simple blood test could reveal risk of skin cancer coming back
6/12/17
1 item of Media coverage
Press/Media: Research
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TIMES HIGHER EDUCATION: Collaboration on a grand scale: negotiating big science
Caroline Dive
28/04/17
1 Media contribution
Press/Media: Expert comment
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The Big Bang science fair
Patricia Muller & Lydia Aschauer
13/03/16
1 item of Media coverage
Press/Media: Other
Student theses
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A potential role for SOX7 in leukaemogenesis
Author: Cuvertino, S., 1 Aug 2015Supervisor: Kouskoff, V. (Supervisor)
Student thesis: Phd
File -
Cardiotoxicity from Cancer Therapy: A Translational Approach to Biomarker Development
Author: Cove-Smith, L., 1 Aug 2016Supervisor: Jackson, A. (Supervisor), Dive, C. (Supervisor), Radford, J. (Supervisor), Linton, K. (Supervisor) & Schmitt, M. (Supervisor)
Student thesis: Unknown
File -
Direct reprogramming of murine fibroblasts to blood
Author: Florkowska, M., 1 Aug 2016Supervisor: Kouskoff, V. (Supervisor) & Lacaud, G. (Supervisor)
Student thesis: Phd
File -
Evaluation of a panel of angiogenesis biomarkers in patients with colorectal cancer.
Author: Marti Marti, F., 1 Aug 2016Supervisor: Dive, C. (Supervisor) & Jayson, G. (Supervisor)
Student thesis: Unknown
File -
FUNCTIONAL CHARACTERISATION OF THE TRANSCRIPTIONAL REGULATORS FOXC1 AND IRX3 IN ACUTE MYELOID LEUKAEMIA
Author: Somerville, T., 31 Dec 2015Supervisor: Kouskoff, V. (Supervisor) & Somervaille, T. (Supervisor)
Student thesis: Unknown
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