Research output per year
Research output per year
Organization profile
The Cancer Research UK Manchester Institute is a leading cancer research institute within The University of Manchester, core funded by Cancer Research UK, the largest independent cancer research organisation in the world.
Our research spans the whole spectrum of cancer research, from programmes investigating the molecular and cellular basis of cancer, to those focused on translational research and the development of therapeutics. The Institute is based in the Paterson Building which is adjacent to The Christie NHS Foundation Trust.
The Institute is a partner in the CRUK Centre of Excellence for Lung Cancer and is also a key part of the Belfast-Manchester Movember Centre of Excellence for Prostate Cancer.
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy: final results from two randomised phase 3 trials of the STAMPEDE platform protocol.
STAMPEDE Investigators, 1 May 2023, In: The Lancet. Oncology.Research output: Contribution to journal › Article › peer-review
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A randomised trial of a T2-composite-biomarker strategy adjusting corticosteroidtreatment in severe asthma, a post- hoc analysis by sex
RASPUK Investigators, 5 Jan 2023, In: The journal of allergy and clinical immunology. In practice.Research output: Contribution to journal › Article › peer-review
Open Access -
A three-gene leukaemic stem cell signature score is robustly prognostic in chronic myelomonocytic leukaemia
Wang, Y-H., Yao, C-Y., Lin, C-C., Gurashi, K., Amaral, F. M. R., Bossenbroek, H., Jerez, A., Somervaille, T. C. P., Binder, M., Patnaik, M. M., Hou, H-A., Chou, W-C., Batta, K., Wiseman, D. H. & Tien, H-F., 1 Apr 2023, In: British Journal of Haematology. 201, 2, p. 302-307 6 p.Research output: Contribution to journal › Article › peer-review
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Autocrine activation of MAPK-signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells
Steiner, I., Flores-Tellez, T. D. N. J., Mével, R., Ali, A., Wang, P., Schofield, P., Behan, C., Forsythe, N., Ashton, G., Taylor, C., Mills, I. G., Oliveira, P., McDade, S., Zaiss, D. M., Choudhury, A., Lacaud, G. & Baena Chaparro, E., 23 Mar 2023, (Accepted/In press) In: Cell Reports.Research output: Contribution to journal › Article › peer-review
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Clinical testing of transcriptome-wide expression profiles in high-risk localized and metastatic prostate cancer starting androgen deprivation therapy: an ancillary study of the STAMPEDE abiraterone Phase 3 trial
Attard, G., Parry, M., Grist, E., Mendes, L., Dutey-Magni, P., Sachdeva, A., Brawley, C., Murphy, L., Proudfoot, J., Lall, S., Liu, Y., Friedrich, S., Ismail, M., Hoyle, A., Ali, A., Haran, A., Wingate, A., Zakka, L., Wetterskog, D., Amos, C., & 26 others, 8 Feb 2023Research output: Other contribution
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NIHR Manchester Biomedical Research Centre
Bruce, I., Lord, G., Lennon, R., Black, G., Wedge, D., Morris, A., Hussell, T., Sharrocks, A., Stivaros, S., Buch, M., Gough, J., Kostarelos, K., Thistlethwaite, F., Kadler, K., Barton, A., Hyrich, K., Mcbeth, J., O'Neill, T., Vestbo, J., Simpson, A., Singh, S., Smith, J., Felton, T., Murray, C., Griffiths, C., Cullum, N., Rhodes, L., Warren, R., Paus, R., Dumville, J., Viros Usandizaga, A., Keavney, B., Tomaszewski, M., Allan, S., Body, R., Cartwright, E., Heagerty, A., Kalra, P., Miller, C., Rutter, M., Smith, C., Trafford, A., Evans, D., Crosbie, E., Crosbie, P., Harvie, M., Howell, S., Renehan, A., Dive, C., Blackhall, F., Landers, D., Krebs, M., Cook, N., Clarke, R., Taylor, S., Jorgensen, C., Lorigan, P., Jayson, G., Valle, J., Mccabe, M., Armstrong, A., Freitas, A., Illidge, T., Choudhury, A., Hoskin, P., West, C., Van Herk, M., Faivre-Finn, C., Bristow, R., Kirkby, K., Birtle, A., Mackay, R., Radford, J., Linton, K., Higham, C., Munro, K., Plack, C., Arden Armitage, C., Bruce, I., Moore, D., Saunders, G., Stone, M., Haddock, G., Lewis, S., Elliott, R., Green, J., Lovell, K., Morrison, A., Shaw, J., Bucci, S., Ainsworth, J., Webb, R., Newman, W., Banka, S., Clayton-Smith, J., Payne, K., Moldovan, R., Wynn, R. & Jones, S.
1/12/22 → 30/11/27
Project: Research
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Centre for Digital Trust and Society
Barrett, E., Allmendinger, R., Elliot, M., Lord, N., Cordeiro, L., Gibson, R., Papamarkou, T., Dresner, D., Buil Gil, D., Aldridge, J., Duncan, P., Banach, R., Brown, G., Dennis, L., Fisher, M., Korovin, K., Kotselidis, C., Luján, M., Mustafa, M., Olivier, P., Reger, G., Zhang, N., Hodgkinson, G., Gulati, S., Ainsworth, J., Chen, Y., Green, B., Healey, M., Uyarra, E., Zachariadis, M., Little, C., Mackey, E., Nenadic, G., Keane, J., Shlomo, N., Laskowski, N., Jarwar, M. A., Shariati Samani, S., Smith, D., Kambites, M., Thorpe, M., Rowley, P., Flynn, S., Turner, P., Wainwright, V., Czerwinsky, A., Nini, A., Broad, R., Shute, J., Deakin, J., Taboada, P., Knight, P., Hutchings, S., Whyte, J., Tolz-Zilitinkevic, V., Pilkington, H., Guharoy, S., Nicolo, A., Reggiani, C., Garcia Oliva, J., Van Someren, A., Bon, E., Cantijoch Cunill, M., Koch, D. & Chen, Y.
11/05/21 → …
Project: Other
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NIHR Biomedical Research Centre: Cancer Precision Medicine Theme.
Dive, C., Baena Chaparro, E., Blackhall, F., Bruce, I., Bundred, N., Carter, L., Clarke, R., Cook, N., Crosbie, P., Evans, D., Harris, J., Hawkins, R., Hussell, T., Illidge, T., Jayson, G., Jorgensen, C., Kirwan, C., Kostarelos, K., Krebs, M., Lorigan, P., Marais, R., Marshall, K., Metcalf, R., Payne, K., Radford, J., Somervaille, T., Springer, C., Taylor, S., Thistlethwaite, F., Viros Usandizaga, A. & Zelenay, S.
1/04/17 → 31/03/19
Project: Research
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Noncoding RNA Derived Classifiers as Biomarkers of Patient Response to Therapy.
Miller, C., Baena Chaparro, E., Choudhury, A., Dive, C. & Marais, R.
18/10/16 → 17/10/20
Project: Research
Activities
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Cancer Research UK LTD (External organisation)
Iain Hagan (Academic expert member)
1 May 2019 → 2 May 2019Activity: Membership › Membership of committee
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Conferences Jacques Monod:Mitotic and Meiotic Cell Cycle control and execution
Iain Hagan (Chair) & Katja Wassman (Co-Chair)
8 Apr 2019 → 12 Apr 2019Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc
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Cancer Research UK LTD (External organisation)
Iain Hagan (Academic expert member)
11 Mar 2019 → 12 Mar 2019Activity: Membership › Membership of committee
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The Wellcome Trust (External organisation)
Iain Hagan (Academic expert member)
15 Jan 2019 → 15 Jan 2022Activity: Membership › Membership of committee
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American Association for Cancer Research (External organisation)
Patricia Muller (Academic expert member)
24 Dec 2018 → 24 Dec 2019Activity: Membership › Membership of professional association
Datasets
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Proteomic analysis of Rac1 signaling regulation by guanine nucleotide exchange factors
Marei, H. (Contributor), Carpy, A. (Contributor), Macek, B. (Contributor) & Malliri, A. (Contributor), figshare , 1 Jun 2016
DOI: 10.6084/m9.figshare.c.3212578.v2, https://figshare.com/collections/Proteomic_Analysis_of_Rac1_Signalling_Regulation_by_Guanine_Nucleotide_Exchange_Factors/3212578/2
Dataset
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Neutrophil depletion does not alter the immune infiltrate of COX-2-competent and deficient tumors
Bonavita, E. (Contributor), Mendeley Data, 25 Oct 2020
DOI: 10.17632/gngxk9mjkm.1, https://data.mendeley.com/datasets/gngxk9mjkm
Dataset
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Functional networks inference from rule-based machine learning models
Lazzarini, N. (Contributor), Widera, P. (Contributor), Williamson, S. (Contributor), Heer, R. (Contributor), Krasnogor, N. (Contributor) & Bacardit, J. (Contributor), figshare , 5 Sep 2016
DOI: 10.6084/m9.figshare.c.3629150.v1, https://figshare.com/collections/Functional_networks_inference_from_rule-based_machine_learning_models/3629150/1
Dataset
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Genetic susceptibility to allergic bronchopulmonary aspergillosis in asthma: a genetic association study
Overton, N. (Contributor), Denning, D. (Contributor), Bowyer, P. (Contributor) & Simpson, A. (Contributor), figshare , 27 Sep 2016
DOI: 10.6084/m9.figshare.c.3627629.v1, https://figshare.com/collections/Genetic_susceptibility_to_allergic_bronchopulmonary_aspergillosis_in_asthma_a_genetic_association_study/3627629/1
Dataset
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Investigation of cell fate decision in Schizosaccharomyces pombe by ncRNA annotation and statistical analyses
Bitton, D. (Contributor), Grallert, A. (Contributor), Scutt, P. J. (Contributor), Yates, T. (Contributor), Li, Y. (Contributor), Bradford, J. R. (Contributor), Hey, Y. (Contributor), Pepper, S. D. (Contributor), Hagan, I. (Contributor) & Miller, C. (Contributor), PANGAEA, 1 Jan 2012
DOI: 10.1594/pangaea.775713, https://doi.pangaea.de/10.1594/PANGAEA.775713
Dataset
Prizes
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ASH/EHA Translational Research Training in Haematology Fellowship 2017
Wiseman, Daniel (Recipient), Jan 2017
Prize: Fellowship awarded competitively
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Cancer Research UK Future Leaders in Cancer Research Prize
Zelenay, Santiago (Recipient), 6 Nov 2017
Prize: Prize (including medals and awards)
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CRUK Advanced Clinician Scientist Fellowship
O'Connor, James (Recipient), 1 Jun 2016
Prize: Fellowship awarded competitively
Press/Media
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MAIL ONLINE: New blood test could spare thousands of lung cancer patients from chemotherapy by spotting if tumour will spread
Caroline Dive
7/10/19
1 Media contribution
Press/Media: Research
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MANCHESTER EVENING NEWS: New Year Honours 2018
Diane Coyle, Caroline Dive, CEM Griffiths & Vikas Shah
29/12/17
1 Media contribution
Press/Media: Other
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MANCHESTER EVENING NEWS: Simple blood test could reveal risk of skin cancer coming back
6/12/17
1 item of Media coverage
Press/Media: Research
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TIMES HIGHER EDUCATION: Collaboration on a grand scale: negotiating big science
Caroline Dive
28/04/17
1 Media contribution
Press/Media: Expert comment
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The Big Bang science fair
Patricia Muller & Lydia Aschauer
13/03/16
1 item of Media coverage
Press/Media: Other