Research output per year
Research output per year
Organisation profile
Organisation profile
The Cancer Research UK Manchester Institute is a leading cancer research institute within The University of Manchester, core funded by Cancer Research UK, the largest independent cancer research organisation in the world.
Our research spans the whole spectrum of cancer research, from programmes investigating the molecular and cellular basis of cancer, to those focused on translational research and the development of therapeutics. The Institute is based in the Paterson Building which is adjacent to The Christie NHS Foundation Trust.
The Institute is a partner in the CRUK Centre of Excellence for Lung Cancer and is also a key part of the Belfast-Manchester Movember Centre of Excellence for Prostate Cancer.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Rosamund Clifford
- Cancer Research UK Manchester Institute - Senior Scientific Officer
Person: Technical
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Aligning management of chronic cough in asthma with BTS/NICE/SIGN guidance
Marsden, P., Smith, J. A., Birring, S. S., Gruffydd-Jones, K., Haines, J., McGarvey, L. P., Martin, M., Morice, A., O'Hara, J., Thomas, M. & Parker, S. M., 13 Mar 2026, (E-pub ahead of print) In: Thorax.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Biallelic variants in RNU2-2 cause a remarkably frequent developmental and epileptic encephalopathy
Jackson, A., Blakes, A. J. M., Alhaddad, B., Henry, O. J., Delgado-Vega, A. M., Wall, E., Abdelhadi, O., Agrawal, S., Bakur, K., Blair, E., Brady, A. F., Brittain, H., Chandler, K. E., Clarke, N., Danelli, M., Drinkall, N., Duba, I., Elmslie, F., Ellingford, J. & Ewans, L. J. & 42 others, , 1 Apr 2026, In: Nature Genetics. p. 798–809Research output: Contribution to journal › Article › peer-review
Open Access -
CCR7+ activated dendritic cells are essential for spontaneous and immunotherapy-driven anti-tumor immunity
Koufaki, M. A., Richardson, E., Bonavita, E., Reeves, R., Moeini, A., Chiang, S.-C., Banyard, A., Russo, M., Earnshaw, C. H., Bell, C. R., Flanagan, E., Pelly, V. S., Nebot-Bral, L., Pidoux, A., Dunn, P., Sahoo, S., Henri, S., Malissen, B., MacDonald, A. S. & Moncaut, N. & 1 others, , 4 Aug 2026, In: Immunity.Research output: Contribution to journal › Article › peer-review
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CDK1-Cyclin B mediated phosphorylation of PP2A-B56 on B56Par1.T73T75 controls mitotic entry timing and Schizosaccharomyces pombe cell size
Halova, L., Connolly, Y., Smith, D., Petersen, J. & Hagan, I., 19 Aug 2026, In: Open Biology.Research output: Contribution to journal › Article › peer-review
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Contrasting features of papillary and chromophobe renal cell carcinoma revealed by whole genome sequencing
Culliford, R., Mills, C., Chubb, D., Kinnersley, B., Sud, A., Cornish, A. J., Browning, L., Lawrence, S. E. D., Bentham, R., Frangou, A., Gruber, A. J., Litchfield, K., Wedge, D. C., Larkin, J., Turajlic, S. & Houlston, R. S., 21 Jan 2026, (E-pub ahead of print) In: Molecular Cancer Research.Research output: Contribution to journal › Article › peer-review
Open Access
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Unraveling the Molecular Mechanisms driving Endothelial-to-Haematopoietic Transition during Blood Formation
Lacaud, G. (PI) & Iqbal, M. (CoI)
2/02/26 → 1/02/29
Project: Research
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RISE : Reducing Immune Stress from Excess Cytokine Release in Advanced Therapies
Lim, J. (PI), Valletta, S. (CoI), Frangi, A. F. (CoI), Parkes, M. (CoI), Giampazolias, E. (CoI) & Hughes-Noehrer, L. (CoI)
1/10/25 → 30/09/30
Project: Research
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Investigating the role of RAC1 signalling in small cell lung cancer plasticity
Malliri, A. (PI), Baker, M. (CoI), Dive, C. (CoI) & Simpson, K. (CoI)
1/04/25 → 31/03/28
Project: Research
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Supporting Research and Researchers through the deployment of Digital Notebooks: A framework for implementation and impact
Stewart, A. (PI), Bird, J. (CoI) & Porter, A. (CoI)
31/01/25 → 30/01/27
Project: Research
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DONATION: HereDitary homologous recOmbination repair deficiency (hHRD): defining and modeling the evolutioNary ecosystem to identify novel candidates for cancer eArly deTection and InterceptiOn, the paNreatic ductal adenocarcinoma (PDAC) paradigm.
Woodward, E. (PI), Jorgensen, C. (CoI), Weaver, J. (CoI) & Wedge, D. (CoI)
1/06/24 → 31/05/27
Project: Research
Impacts
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Molecular markers and drug development leading to improvements in radiotherapy.
Stratford, I. (Participant), Williams, K. (Participant), West, C. (Participant), Dive, C. (Participant), Airley, R. (Participant), Eustace, A. (Participant) & Shannon, A. (Participant)
Impact: Health impacts
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Online tool (CORONET) created to support clinical decisions regarding hospital admissions or discharge in cancer patients presenting with symptoms of COVID-19 and the likely severity of illness
Lee, R. (Corresponding participant), Dive, C. (Participant) & Armstrong, A. (Participant)
Impact: Health and wellbeing
Activities
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Cancer Research UK LTD (External organisation)
Hagan, I. (Academic expert member)
1 May 2019 → 2 May 2019Activity: Membership › Membership of committee › Research
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Conferences Jacques Monod:Mitotic and Meiotic Cell Cycle control and execution
Hagan, I. (Chair) & Wassman, K. (Co-Chair)
8 Apr 2019 → 12 Apr 2019Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc › Research
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Cancer Research UK LTD (External organisation)
Hagan, I. (Academic expert member)
11 Mar 2019 → 12 Mar 2019Activity: Membership › Membership of committee › Research
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The Wellcome Trust (External organisation)
Hagan, I. (Academic expert member)
15 Jan 2019 → 15 Jan 2022Activity: Membership › Membership of committee › Research
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American Association for Cancer Research (External organisation)
Muller, P. (Academic expert member)
24 Dec 2018 → 24 Dec 2019Activity: Membership › Membership of professional association › Research
Datasets
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Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia
Somervaille, T. (Creator), PRoteomics IDEntifications Database, 2021
https://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD027740
Dataset
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A microenvironment-inspired synthetic 3D model for pancreatic ductal adenocarcinoma organoids - Pancreas matrisome atlas
Jorgensen, C. (Creator), PRoteomics IDEntifications Database, 2021
DOI: 10.6019/PXD022555, http://central.proteomexchange.org/cgi/GetDataset?ID=PXD022555
Dataset
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A microenvironment-inspired synthetic 3D model for pancreatic ductal adenocarcinoma organoids - PDA Matrisome
Jorgensen, C. (Creator), PRoteomics IDEntifications Database, 2021
DOI: 10.6019/PXD022767, http://central.proteomexchange.org/cgi/GetDataset?ID=PXD022767
Dataset
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A microenvironment-inspired synthetic 3D model for pancreatic ductal adenocarcinoma organoids - CDM Sets
Jorgensen, C. (Creator), PRoteomics IDEntifications Database, 2021
https://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD022509
Dataset
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A microenvironment-inspired synthetic 3D model for pancreatic ductal adenocarcinoma organoids - 3D PEG-CBF-0.5 MS
Jorgensen, C. (Creator), PRoteomics IDEntifications Database, 2021
DOI: 10.6019/PXD022520, http://central.proteomexchange.org/cgi/GetDataset?ID=PXD022520
Dataset
Prizes
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ASH/EHA Translational Research Training in Haematology Fellowship 2017
Wiseman, D. (Recipient), Jan 2017
Prize: Fellowship awarded competitively
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Cancer Research UK Future Leaders in Cancer Research Prize
Zelenay, S. (Recipient), 6 Nov 2017
Prize: Prize (including medals and awards)
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CRUK Advanced Clinician Scientist Fellowship
O'Connor, J. (Recipient), 1 Jun 2016
Prize: Fellowship awarded competitively
Press/Media
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Scientists unmask immune cells that supercharge the fight against cancer
Koufaki, M. & Zelenay, S.
4/08/26
1 Media contribution
Press/Media: Research
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MAIL ONLINE: New blood test could spare thousands of lung cancer patients from chemotherapy by spotting if tumour will spread
Dive, C.
7/10/19
1 Media contribution
Press/Media: Research
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MANCHESTER EVENING NEWS: New Year Honours 2018
Coyle, D., Dive, C., Griffiths, C. & Shah, V.
29/12/17
1 Media contribution
Press/Media: Other
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MANCHESTER EVENING NEWS: Simple blood test could reveal risk of skin cancer coming back
Marais, R.
6/12/17
1 item of Media coverage
Press/Media: Research
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TIMES HIGHER EDUCATION: Collaboration on a grand scale: negotiating big science
Dive, C.
28/04/17
1 Media contribution
Press/Media: Expert comment