Chemical Biology and Biological Chemistry

Mohamed Amer El-Gazar
- Chemical Biology and Biological Chemistry - Research Fellow
Person: Academic
Rainer Breitling, DrRerNat
- Chemical Biology and Biological Chemistry - Honorary Professor
Person: Academic
Patrick Cai
- Chemical Biology and Biological Chemistry - Chair in Synthetic Genomics
Person: Academic
Jack Connolly
- Chemical Biology and Biological Chemistry - Research Fellow (Actinomycete)
Person: Academic
Neil Dixon
- Chemical Biology and Biological Chemistry - Reader Sustainable Biotechnology
Person: Academic

3,4,6-Tri-O-acetyl-1-S-acetyl-2-deoxy-2-S-phenylthio-α-d-mannopyranoside
Porter, J. & Miller, G. J., Mar 2025, In: MolBank. 2025, 1, M1981.
Research output: Contribution to journal › Article › peer-review

Open Access
3D printed poly(3-hydroxybutyrate-co-3-hydroxyexanoate) scaffolds support chondrogenic potential of human primary chondrocytes during in vitro culture
Pecorini, G., Puppi, D., Richardson, S., Chen, G.-Q. & Domingos, M., 21 Feb 2025, In: Polymer. 320, 128105.
Research output: Contribution to journal › Article › peer-review

Open Access
3′-O-β-Glucosylation of nucleoside analogues using a promiscuous bacterial glycosyltransferase
Dolan, J. P., Keenan, T., Cheallaigh, A. N., Fascione, M. A. & Miller, G. J., 25 Mar 2025, In: RSC Chemical Biology. 6, 6, p. 845-850 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Abstraction hierarchy to define biofoundry workflows and operations for interoperable synthetic biology research and applications
kim, H., Hillson, N., Cho, B. K., Sung, B. H., Lee, D.-H., Kim, D.-M., Oh, M.-K., Chang, M., Jin, Y.-S., Rosser, S. J., Vegh, P., Fragkoudis, R., Feuvre, R. L., Scrutton, N., Storch, M., Seong, W., Freemont, P. & Lee, S.-G., 1 Jul 2025, In: Nature Communications. 16, 6056.
Research output: Contribution to journal › Article › peer-review

Open Access
Adenosine deaminase: structure–activity relationships and harnessing biocatalysis to access purine nucleoside analogues
Wootton, H. S., Maganza-Zurdo, A., Sanghvi, Y. S., Cosgrove, S. C. & Miller, G. J., 2025, (Accepted/In press) In: Trends in Chemistry.
Research output: Contribution to journal › Review article › peer-review

Open Access

2 Not started
19 Active
24 Finished

Engineering Biology Approaches To High Value Speciality Chemicals From Waste Plastics
Wong, L. S. (PI), Barran, P. (CoI) & Green, A. (CoI)
15/09/25 → 14/03/27
Project: Research
Rules of life in CO2-driven microbial communities: Microbiome engineering for a Net Zero future
Nixon, S. (PI), Breitling, R. (CoI), Brockhurst, M. (CoI), Cameron, D. (CoI), Coyte, K. (CoI), Cuellar Franca, R. (CoI), Hollywood, K. (CoI), Johnson, D. (CoI), Pitt, A. (CoI), Quince, C. (CoI), Takano, E. (CoI) & Dixon, N. (PI)
1/01/25 → 31/12/29
Project: Research
International Centre for Enzyme Design (ICED)
Green, A. (PI), Lovelock, S. (CoI) & Turner, N. (CoI)
1/11/24 → 31/10/28
Project: Research
Sustainable biocatalytic approaches to pyridine and piperidine heterocycles
Dixon, N. (PI), Leys, D. (CoI) & Turner, N. (CoI)
1/06/24 → 31/05/27
Project: Research
SafePhage: Engineering synthetic phages with intrinsic biocontainment
Brockhurst, M. (PI) & Cai, P. (CoI)
14/05/24 → 13/05/27
Project: Research

Bio-inspired materials: bespoke spider silk
Takano, E. (Participant)
Impact
Driving the industrial biotechnology revolution: cheaper and more sustainable chemical manufacturing through enzyme discovery, engineering and scale-up
Turner, N. (Participant), Flitsch, S. (Participant), Scrutton, N. (Participant), Micklefield, J. (Participant), Greaney, M. (Participant), Weise, N. (Participant), Hardacre, C. (Participant), Lovelock, S. (Participant) & Green, A. (Participant)
Impact: Economic, Technological, Policy, Awareness and understanding

Department of Chemistry, University of Strathclyde, Glasgow
Jin, Y. (Speaker)
12 Nov 2025
Activity: Talk or presentation › Invited talk › Research
UK Solar Chemicals Network workshop: Beyond Hydrogen
Cobb, S. (Chair), Megarity, C. (Chair) & Cowan, A. J. (Member of programme committee)
12 Nov 2024
Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc › Research
Electrochem 2024 (RSC)
Megarity, C. (Speaker)
11 Sept 2024 → 13 Sept 2024
Activity: Talk or presentation › Oral presentation › Research
38th Topical Meeting of the International Society of Electrochemistry, Manchester, UK
Megarity, C. (Speaker)
8 Sept 2024 → 11 Sept 2024
Activity: Talk or presentation › Oral presentation › Research
75th Annual Meeting of the International Society of Electrochemistry (ISE), Montreal, Canada
Megarity, C. (Keynote speaker)
18 Aug 2024 → 23 Aug 2024
Activity: Talk or presentation › Invited talk › Research

Proteome analsyis of Translocation phenomenon
Dixon, N. (Creator), PRoteomics IDEntifications Database, 2018
DOI: 10.6019/PXD006474, https://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD006474
Dataset
Baseline Proteomics Characterisation of Biomanufacturing Organism Halomonas Bluephagenesis
Scrutton, N. (Creator), PRoteomics IDEntifications Database, 2022
DOI: 10.6019/PXD030494, http://central.proteomexchange.org/cgi/GetDataset?ID=PXD030494
Dataset
SYNBIOCHEM - Combinatorial plasmid libraries for material monomer production in Escherichia coli.
Barran, P. (Contributor), Breitling, R. (Contributor), Carbonell, P. (Creator), Currin, A. (Contributor), Dunstan, M. S. (Contributor), Hollywood, K. A. (Contributor), Jervis, A. J. (Contributor), Le Feuvre, R. (Contributor), Malone, K. J. (Contributor), Matthews, N. E. (Contributor), Micklefield, J. (Contributor), Mulherin, P. (Contributor), Robinson, C. J. (Contributor), Scrutton, N. S. (Contributor), Shapira, P. (Contributor), Spiess, R. (Contributor), Swainston, N. (Contributor), Takano, E. (Contributor), Taylor, S. (Contributor), Turner, N. J. (Contributor) & Yan, C. (Contributor), Mendeley Data, 21 Jan 2020
DOI: 10.17632/t4jtcf9dr2.2, https://data.mendeley.com/datasets/t4jtcf9dr2
Dataset
A versatile route to edge-specific modification of graphene nanoplatelets by electrophilic aromatic substitution
Shellard, P. (Contributor), Srisubin, T. (Contributor), Hartmann, M. (Contributor), Butcher, J. (Contributor), Fei, F. (Contributor), Cox, H. (Contributor), McNamara, T. (Contributor), McArdle, T. (Contributor), Shepherd, A. (Contributor), Jacobs, R. (Contributor), Waigh, T. (Contributor), Flitsch, S. (Contributor) & Blanford, C. (Creator), Mendeley Data, 9 May 2020
DOI: 10.17632/mwrvrcj639.1, https://data.mendeley.com/datasets/mwrvrcj639
Dataset
Ligand docking models of vanillic acid decarboxylase (VdcCD)
Marshall, S. (Creator) & Leys, D. (Supervisor), Zenodo, 14 Jul 2021
DOI: 10.5281/zenodo.5101187
Dataset

2024 ACS Bio & Med Chem Au Rising Star in Biological, Medicinal, and Pharmaceutical Chemistry
Jin, Y. (Recipient), 2024
Prize: Prize (including medals and awards)
2024 RSC Chemistry Biology Interface Horizon Prize: Rita and John Cornforth Award
Jin, Y. (Recipient), 2024
Prize: Prize (including medals and awards)
Academy of Medical Sciences Spring Board Award
Jin, Y. (Recipient), 1 Feb 2018
Prize: Prize (including medals and awards)
BBSRC David Phillip Fellowship
Green, A. (Recipient), 10 Aug 2015
Prize: Fellowship awarded competitively
BBSRC Discovery Fellowship
Rowbotham, J. (Recipient), 2021
Prize: Fellowship awarded competitively

Teaching enzymes new reactions through genetic code expansion and directed evolution
Green, A.
12/09/24
1 Media contribution
Press/Media: Research
THE OBSERVER: The 10 biggest science stories of 2022 – chosen by scientists
Takano, E.
18/12/22
1 Media contribution
Press/Media: Expert comment
Another giant leap for mankind
Roberts, A.
14/08/22
1 item of Media coverage
Press/Media: Other
PHYS.ORG: Newly engineered enzyme speeds up slow organic reaction
Green, A.
24/05/22
1 item of Media coverage
Press/Media: Research
BBC CLICK: Space homes
Koncherry, V. & Roberts, A.
14/05/22
1 item of Media coverage
Press/Media: Research

Biochemical and Biophysical Sciences Core Facility
Heyes, D. (Senior Technical Specialist), Boothman, C. (Senior Technical Specialist), Cliffe, L. (Technical Specialist), Dunstan, M. (Senior Technical Specialist), Golovanova, M. (Senior Technician), Hoeven, R. (Technical Specialist), Lopez Perez, R. (Senior Technician), Sakuma, M. (Senior Technician), Tait, S. (Senior Technician) & Tilakaratna, V. (Senior Technician)
FSE Research
Facility/equipment: Facility
Biochemical preparation facility
Golovanova, M. (Senior Technician), Lopez Perez, R. (Senior Technician), Sakuma, M. (Senior Technician), Tait, S. (Senior Technician) & Tilakaratna, V. (Senior Technician)
FSE Research
Facility/equipment: Facility

Chemical Biology and Biological Chemistry

Collaborations and top research areas from the last five years

Profiles

Research output

Projects

Impacts

Activities

Datasets

Prizes

Press/Media

Equipment