Organisation profile
Organisation profile
We have a long history of high-quality, impactful dental, oral and craniofacial research. Our internationally renowned research is funded by research councils, the NHS, the EU, charity, and industry.
Our research
Dentistry has two principal themes:
- Basic Dental Sciences;
- Applied Health Sciences.
Basic Dental Sciences
Our researchers within this theme aim to improve craniofacial health by adding to the understanding of the mechanisms underlying health and disease, and by developing and improving health technologies and biomaterials.
Biomaterials and biomechanics
Our internationally recognised research group conducts high-level research at the clinical/basic science interface. We examine many biomaterials for operative dentistry, prosthodontics, implantology, endodontics, orthodontics, oral surgery, plus research on orthopaedic materials.
Our research is focused on the characterisation of the existing biomaterials and the development of new ones, with special interest in polymers, composites and ceramics. We perform laboratory tests that simulate the oral environment aiming to predict the clinical behaviour of the biomaterials.
New technologies applied in digital dentistry, such as scanners, CAD/CAM subtractive and additive (3D printing) systems, are investigated in our laboratory and clinical settings. Research projects on artificial intelligence in dentistry are ongoing.
Our group has a long history of collaboration with national and international universities, and the industry. We have been actively engaged with international dental research organisations, such as the Academy of Dental Materials.
Researchers:
- Prof Nick Silikas
- Dr Marcia Borba
- Prof Jukka Matinlinna
- Prof Julian Satterthwaite
- Dr Evgeny Kushnerev
Craniofacial genetics and development
Craniofacial anomalies are among the most common and distressing congenital malformations affecting humans. Research in our laboratories uses systems-level approaches to delineate gene regulatory networks underlying development of the lip and palate and dissect how their modification is related to the pathogenesis of cleft lip and palate.
Research is also developed using the latest genomics technologies to decipher the transcriptional networks that guide neural crest cells cell into forming diverse anatomical structures such as the face, the ear and the heart and shape the countless anatomical features of vertebrates.
Researchers:
Applied Health Sciences
Our Applied Health Sciences researchers work collaboratively across a broad range of research areas with the aim of improving oral health and with a strong focus on reducing oral health inequalities. We are experienced in carrying out oral health research across the life course (including the general public, children, those living with disabilities and older adults).
We develop oral health research in the Colgate-Palmolive Dental Health Unit, a 50-year successful partnership between The University of Manchester and industry. The unit has contributed to major scientific advances in dental health and continues to undertake world-leading research.
Within the Division, our research in Dental Public Health and Primary Care has utilised a range of methodological approaches including randomised clinical trials, observational studies, working with routinely collected data and conducting evidence synthesis to address priority questions.
Given the high rates of inappropriate antibiotic prescribing by primary care dentists around the world, our researchers are developing and evaluating evidence-based dental antibiotic stewardship interventions, underpinned by behavioural science. In addition to clinical primary care research, our researchers are also undertaking NIHR funded work to develop ways to improve how primary care dental teams engage in research.
With individual behaviours key for the development and progression of many dental diseases, our researchers are looking into ways of incorporating Behavioural Science into oral health. Areas they are researching include the development of behaviour change interventions, use of behavioural insights to understand oral health behaviours and finally, exploring the role of digital technologies in supporting long-lasting changes and achieving better oral health outcomes.
Our research within Health Service Delivery focuses on improving the quality and timing of oral care. Our applied health research includes the evaluation of Digital Health Technologies with the aim of improving oral health services.
We are world-leading in our Evidence Synthesis research and host Cochrane Oral Health. Our evidence syntheses cover a wide range of oral health topics seeking to elucidate the evidence for clinical practice and patient care. We work closely with international stakeholders to ensure our evidence addresses the needs of health care providers, the public and policy makers. Our evidence has been used to inform national and international clinical practice guidelines resulting in substantial real-world impact.
Researchers:
- Prof Anne-Marie Glenny
- Prof Tanya Walsh
- Prof Julian Yates
- Dr Lucy O’Malley
- Dr Michaela Goodwin
- Dr Wendy Thompson
- Dr Matt Byrne
- Prof Janet Clarkson
- Dr Ali Feizollah
- Dr George Kitsaras
- Sharon Lewis
- Dr Chiu-Yi Lin
- Dr Phil Riley
- Prof Martin Tickle (Emeritus)
- Prof Helen Worthington (Emeritus)
Head of Division
Deputy Head of Division
Our researchers
View list of researchers within the Division
Contact
Collaborations and top research areas from the last five years
Profiles
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Craig Barclay, BDS PhD MPhil FDS RCPS DRD RCS MRD RCS FDS RCPS (Rest)
- Division of Dentistry (L5) - MAHSC Honorary Clinical Chair
Person: Academic
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Nicoletta Bobola, Ph.D
- Division of Dentistry (L5) - Chair in Developmental Biol and Genomics
Person: Academic
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A novel posterior occlusal splint improves symptoms and prognosis of coexisting temporomandibular disorders and deep bite: a retrospective study
Yuan, Y., Wu, A., Fan, J., Lin, Y., Liu, Z., Huang, L., Feng, J., Zhang, Q., Liu, Z., Li, X. & Cao, W. (Corresponding), 9 Feb 2026, In: Clinical Oral Investigations. 30, 76.Research output: Contribution to journal › Article › peer-review
Open Access -
Antibacterial and Antibiofilm Properties of h-BNNS-reinforced Light-curable RBC Against S. mutans
Fan, J., Rahman, A., Camilleri, J., Gough, J., Silikas, N. & Watts, D. C., Mar 2026.Research output: Contribution to conference › Other › peer-review
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Behavioural interventions for improving oral hygiene in adults with periodontal diseases
O'Malley, L., Lewis, S. R., Preshaw, P. M., Riley, P., Adair, P., Edwards, M. L. E., Raison, H., Byrne, M. J., Kitsaras, G. & Jervøe-Storm, P.-M., 28 Jan 2026, In: The Cochrane database of systematic reviews. 1, CD012049.Research output: Contribution to journal › Review article › peer-review
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Celebrating 30 Years of Cochrane Oral Health: A Legacy of Evidence and Impact
Clarkson, J., Walsh, T., Lewis, S., Riley, P., O'Malley, L. & Glenny, A.-M., 3 Jan 2026, (E-pub ahead of print) In: Journal of Evidence-Based Dental Practice. 102227.Research output: Contribution to journal › Article › peer-review
Open Access -
Drinking Water Hardness (as a Proxy for Calcium) Significantly Modifies the Relationship Between Dental Caries Prevalence in 5 Year Old Children and Drinking Water Fluoride and Socio-economic Inequalities in England
Mehrabi, M., Han, Y., Moore, D., Ascott, M. J., Glenny, A.-M. & Polya, D., 18 May 2026, In: Exposure and Health.Research output: Contribution to journal › Article › peer-review
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Challenging the impossible: Questioning the reconstruction of ancient Egyptian faces through interdisciplinary collective approaches from digital, medical and arts methods.
Foster, D. (PI), Price, C. (CoI), Yates, J. (CoI), Warr, C. (CoI), Giles, M. (CoI) & Amano, K. (CoI)
1/08/25 → 31/07/26
Project: Research
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Image Cell sorting: Integrating cell image analysis into sorting approaches to Revolutionise Cell biology at UoM
Konkel, J. (PI), Allen, J. (CoI), Ashe, H. (CoI), Bechtold, D. (CoI), Bertuzzi, M. (CoI), Bobola, N. (CoI), Brough, D. (CoI), Else, K. (CoI), Grainger, J. (CoI), Grencis, R. (CoI), Hepworth, M. (CoI), Howell, G. (CoI), Lopez-Castejon, G. (CoI), Mcfiggans, G. (CoI), O'Neill, C. (CoI), Sharrocks, A. (CoI), Thornton, D. (CoI), Voliotis, A. (CoI) & Worboys, J. (CoI)
1/08/25 → 31/07/26
Project: Research
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Evolutionary ancient transcription factors: master keys to unlock lineage differentiation?
Bobola, N. (PI) & Birket, M. (CoI)
1/10/23 → 30/09/26
Project: Research
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AMFaces: Advanced Additive Manufacturing of User-Focused Facial Prostheses with Real-Life Colour Appearance
Foster, D. (PI), Amano, K. (Researcher), Cartmell, S. (CoI) & Yates, J. (CoI)
1/04/23 → 31/03/28
Project: Research
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Centre for Crisis Studies and Mitigation
Schultz, D. (PI), Parkes, B. (CoI), Allen, O. (CoI), Mccormick Kilbride, B. (CoI), Jankovic, V. (CoI), Müller, T. (CoI), Foster, T. (CoI), Foster, A. (CoI), Panteli, M. (CoI), Sedighi, M. (CoI), Morgan, J. (CoI), Souvannaseng, P. (CoI), Hadi Mosleh, M. (CoI), Taithe, B. (CoI), Lombardi, D. (CoI) & Clay, G. (CoI)
1/11/19 → …
Project: Research
Impacts
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Cochrane Oral Health Group leads the international evidence base for oral health: Antibiotics for the prevention of bacterial endocarditis
Hooper, L. (Participant), Oliver, R. (Participant) & Worthington, H. (Participant)
Impact: Health impacts
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Encouraging and enabling dental teams and the wider public to participate in efforts to reduce Antibiotic Resistance (ABR) and Antimicrobial resistance (AMR)
Thompson, W. (Corresponding participant)
Impact: Health and wellbeing
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Evaluating an alternative child friendly dental pathway for paediatric patients
Goodwin, M. (Corresponding participant), Walsh, T. (Participant), Pretty, I. (Participant), Allen, T. (Participant) & Kitsaras, G. (Participant)
Impact: Health and wellbeing
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Highlighting the increase in antibiotic prescribing by dental practices during Covid-19 to encourage improvements in service delivery and dental antibiotic stewardship
Thompson, W. (Corresponding participant)
Impact: Health and wellbeing, Awareness and understanding, Attitudes and behaviours, Policy
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Informing policymakers on the effectiveness and cost-effectiveness of water fluoridation to inform policy
Goodwin, M. (Corresponding participant), Pretty, I. (Participant), Walsh, T. (Participant), Birch, S. (Participant), Tickle, M. (Participant), Sutton, M. (Participant), Allen, T. (Participant), Whittaker, W. (Participant), Emsley, R. (Participant), Glenny, A.-M. (Participant), Worthington, H. (Participant), Clarkson, J. (Participant), Lewis, S. (Participant), Riley, P. (Participant) & Moore, D. (Participant)
Impact: Health and wellbeing, Policy
Activities
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Oral Health & AMR - UNGA Side meeting
Thompson, W. (Speaker)
24 Sept 2025Activity: Talk or presentation › Invited talk › Teaching and Research
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Dental Materials Research: Lessons Learned and Future Perspectives
Silikas, N. (Speaker)
4 Sept 2025Activity: Talk or presentation › Invited talk › Research
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Leveraging technology to provide accessible, inclusive learning opportunities for young people to enhance their understanding of dental education and the profession through an online Summer School
Kendall, J. (Speaker) & Thagia, S. (Speaker)
2 Jul 2025Activity: Talk or presentation › Oral presentation › Teaching and Research
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International Dental Journal (Journal)
Byrne, M. (Peer reviewer of publications)
30 Jun 2025Activity: Publication peer-review and editorial work › Publication peer-review › Research
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IADR Barcelona
Mossey, P. (Chair), Thompson, W. (Co-Chair) & Butali, A. (Organiser)
28 Jun 2025Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc › Research
Prizes
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2020 AADR/IADR William J. Gies Award
Dixon, M. (Recipient), 6 Jan 2020
Prize: Prize (including medals and awards)
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Academic Achievement Award
Dave, M. (Recipient), 13 Jun 2017
Prize: Prize (including medals and awards)
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Press/Media
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Why is movement important for children's wellbeing? The psychology behind Moodboosters
9/05/25
1 Media contribution
Press/Media: Expert comment
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British Dental Association send open letter to UK government urging action on unmet need and avoidable antibiotic prescribing in dentistry
9/03/25 → 12/03/25
5 Media contributions
Press/Media: Research
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Future benefits of water fluoridation not guaranteed, study shows
Moore, D. & Pretty, I.
15/01/25
1 Media contribution
Press/Media: Research
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Mitigating the risks of antimicrobial failure
11/10/24
1 Media contribution
Press/Media: Expert comment
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Water fluoridation ‘less effective’ than in the past –study
O'Malley, L., Glenny, A.-M. & Walsh, T.
3/10/24 → 4/10/24
4 Media contributions
Press/Media: Research
Student theses
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3D Printed Denture Materials: Key Aspects of their Physico-Mechanical and Biological Properties
Altarazi, A. (Author), Haider, J. (Co Supervisor), Devlin, H. (Main Supervisor) & Silikas, N. (Co Supervisor), 1 Jan 1824Student thesis: Phd
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A Comparative Investigation of the Physical and Mechanical Properties of Conventional and Light-Cured Denture Base Materials
Alhotan, A. (Author), 8 Aug 2017Student thesis: Master of Philosophy
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A Contemporary Evaluation of Water Fluoridation Using Real World Evidence
Moore, D. (Author), Walsh, T. (Main Supervisor) & Goodwin, M. (Co Supervisor), 12 Apr 2023Student thesis: Phd
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An Evaluation of Handling and Physico - Mechanical Properties of Resin-Composite Materials
Alahdal, K. Y. M. (Author), Silikas, N. (Main Supervisor) & Watts, D. C. (Co Supervisor), 9 Dec 2015Student thesis: Phd
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An evaluation of Physico - Mechanical properties of Core build-up materials in relation to endodontics
Zankuli, M. (Author), 30 Sept 2014Student thesis: Phd
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