Division of Developmental Biology & Medicine (L5)

John Aplin, MA, PhD
- john.aplinmanchester.acuk
- Division of Developmental Biology & Medicine (L5) - Professor
- FBMH Faculty Office Administration (L5) - Honorary Professor
Person: Academic
Bernadette Baker
- Division of Developmental Biology & Medicine (L5) - Honorary Research Associate
Person: Academic
Kylie Belchamber
- Division of Developmental Biology & Medicine (L5) - Lecturer in Maternal and Foetal Health
Person: Academic
Daimark Bennett
- Division of Developmental Biology & Medicine (L5) - Lecturer in Developmental Biology
Person: Academic
Veronica Biga, BEng
- Division of Developmental Biology & Medicine (L5) - Research Fellow
Person: Academic

Cellular signalling protrusions enable dynamic distant contacts in spinal cord neurogenesis
Hawley, J., Lea, R., Biga, V., Papalopulu, N. & Manning, C., 15 Jan 2025, In: Biology Open. 14, 1, bio061765.
Research output: Contribution to journal › Article › peer-review

Open Access
Epigenome and transcriptome changes in KMT2D-related Kabuki syndrome Type 1 iPSCs, neuronal progenitors and cortical neurons
Cuvertino, S., Martirosian, E., Cheng, P., Garner, T., Jackson, A., Sharrocks, A. D., Kimber, S. J. & Banka, S., 6 Feb 2025
Research output: Other contribution
Fathers' experiences of perinatal death following miscarriage, stillbirth, and neonatal death: A meta-ethnography
Blocksidge, H., Wittkowski, A., Heazell, A. E. P. & Smith, D. M., 25 Jan 2025, (E-pub ahead of print) In: Death Studies. p. 1-17 17 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
4 Downloads (Pure)
Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial
The RECOVERY Collaborative Group, 1 Mar 2025, In: EClinicalMedicine. 81, 103080.
Research output: Contribution to journal › Article › peer-review

Open Access
Life after medicalised conception: an interpretative phenomenological analysis study exploring the experiences of pregnancy and transition to parenthood
Foyston, Z., Higgins, L., Smith, D. & Wittkowski, A., 12 Feb 2025, In: BMC Pregnancy and Childbirth. 25, 146.
Research output: Contribution to journal › Article › peer-review

Open Access

1 Not started
6 Active
7 Finished

Can plant-derived extracellular vesicles improve outcomes in pregnancies complicated by maternal obesity?
Westwood, M. (PI), Cottrell, E. (CoI), Desforges, M. (CoI), Dilworth, M. (CoI), Mann, E. (CoI), Mcbain, A. (CoI) & Stevens, A. (CoI)
1/05/24 → 30/04/27
Project: Research
Tommy's 2024-2025 Annual Budget
Heazell, A. (PI), Aplin, J. (CoI), Brownbill, P. (CoI), Cottrell, E. (CoI), Desforges, M. (CoI), Dilworth, M. (CoI), Higgins, L. (CoI), Johnstone, E. (CoI), Myers, J. (CoI), Palin, V. (CoI), Ruane, P. (CoI), Stevens, A. (CoI), Tropea, T. (CoI), Westwood, M. (CoI) & Worton, S. (CoI)
1/04/24 → 31/03/25
Project: Research
Multi-modal studies to understand pregnancy and prevent stillbirth
Heazell, A. (PI), Brownbill, P. (CoI), Chernyavsky, I. (CoI), Cotter, S. (CoI), Duhig, K. (CoI), Higgins, L. (CoI), Jensen, O. (CoI), Johnstone, E. (CoI) & Whitfield, C. (CoI)
17/10/22 → 31/03/25
Project: Research
A quantitative and dynamical approach to understanding cell state transitions
Papalopulu, N. (PI)
1/04/22 → 31/03/27
Project: Research
Relating Environment-use Scenarios in Pregnancy/Infanthood and Resulting airborne-material Exposures to child-health outcomes (RESPIRE)
Johnstone, E. (PI), Povey, A. (CoI), Van Tongeren, M. (CoI), Ruane, P. (CoI), Bannan, T. (CoI), Gittins, M. (CoI) & Higgins, L. (CoI)
1/11/21 → 31/10/25
Project: Research

Defining the phenotype of severe growth disorders, discovering new genes that control human growth and enhancing clinical practice
Clayton, P. (Participant), Black, G. (Participant), Read, A. (Participant), Manson, F. (Participant), Hanson, D. (Participant) & Patel, L. (Participant)
Impact: Health impacts
Establishment of Tommy’s National Biobank with partners
Johnstone, E. (Participant)
Impact: Health and wellbeing
Innovative 'mymaternity' app helps monitor blood pressure and glucose from home during pregnancy benefitting pregnant women in Greater Manchester
Myers, J. (Corresponding participant)
Impact: Health and wellbeing, Technological
Placenta growth factor (PlGF) blood test for pre-eclampsia recommended by NICE then rolled out more widely by NHS England speeding up diagnosis and helping determine those most at risk
Myers, J. (Corresponding participant), Ormesher, L. (Participant), Johnstone, E. (Participant) & Duhig, K. (Participant)
Impact: Health and wellbeing, Economic
Preventing Stillbirth and Improving the Quality of Care After a Baby Dies
Heazell, A. (Participant), Jones, R. (Participant) & Sibley, C. (Participant)
Impact: Health and wellbeing

PROSPECT : What does it tell us ?
Reid, F. (Speaker)
31 Mar 2023
Activity: Talk or presentation › Invited talk › Research
Step up for Stillbirth
Higgins, L. (Chair)
9 Oct 2021
Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc › Research
International Federation of Placenta Associations Meeting 2021
Desforges, M. (Chair)
1 Sept 2021
Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc › Research
RCOG reproductive medicine clinical studies group (External organisation)
Higgins, L. (Academic expert member)
Mar 2021 → …
Activity: Membership › Membership of committee › Research
MiNESS 20-28 Research Advisory Group
Higgins, L. (Chair)
2021 → …
Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc › Research

FEMINA2
Higgins, L. (Contributor), Johnstone, E. (Contributor) & Heazell, A. (Contributor), Mendeley Data, 22 Oct 2018
DOI: 10.17632/vsxsjhp6n3.1, https://data.mendeley.com/datasets/vsxsjhp6n3
Dataset
Supplementary Material for: The Role of O-GlcNAcylation in Perivascular Adipose Tissue Dysfunction of Offspring of High-Fat Diet-Fed Rats
Zaborska, K. (Contributor), Edwards, G. (Contributor), Austin, C. (Contributor) & Wareing, M. (Contributor), figshare , 3 Apr 2017
DOI: 10.6084/m9.figshare.4811068.v1, https://figshare.com/articles/Supplementary_Material_for_The_Role_of_O-GlcNAcylation_in_Perivascular_Adipose_Tissue_Dysfunction_of_Offspring_of_High-Fat_Diet-Fed_Rats/4811068/1 and one more link, https://ndownloader.figshare.com/files/7959796 (show fewer)
Dataset
Research data for a study on haemoglobin and heme defences - "EVERREST" study
Brook, A. (Creator), Baynes, G. (Creator), Scargill, J. (Creator), Evangelinos, A. (Creator), Brennan-Richardson, C. (Creator), Dow, F. (Creator), Ginsberg, Y. (Creator), Weissbach, T. (Creator), Brodszki, J. (Creator), Hansson, E. (Creator), Diemert, A. (Creator), Hetcher, K. (Creator), Maksym, K. (Creator), Marlow, N. (Creator), Spencer, R. (Creator), David, A. (Creator), Hansson, S. R. (Creator) & Brownbill, P. (Creator), University of Manchester Figshare, 10 Jun 2024
DOI: 10.48420/25924327, https://figshare.manchester.ac.uk/articles/dataset/Research_data_for_a_study_on_haemoglobin_and_heme_defences_-_EVERREST_study/25924327
Dataset
High quality clinical grade human embryonic stem cell lines derived from fresh discarded embryos
Ye, J. (Contributor), Bates, N. (Contributor), Soteriou, D. (Contributor), Grady, L. (Contributor), Edmond, C. (Contributor), Ross, A. (Contributor), Kerby, A. (Contributor), Lewis, P. (Contributor), Adeniyi, T. (Contributor), Ronnie, W. (Contributor), Poulton, K. (Contributor), Lowe, M. (Contributor), Kimber, S. (Contributor) & Brison, D. (Contributor), figshare , 5 Jun 2017
DOI: 10.6084/m9.figshare.c.3795793.v1, https://figshare.com/collections/High_quality_clinical_grade_human_embryonic_stem_cell_lines_derived_from_fresh_discarded_embryos/3795793/1
Dataset
An international internet survey of the experiences of 1,714 mothers with a late stillbirth: the STARS cohort study
Warland, J. (Contributor), O'Brien, L. M. (Contributor), Heazell, A. (Contributor) & Mitchell, E. A. (Contributor), figshare , 15 Aug 2015
DOI: 10.6084/m9.figshare.c.3640913.v1, https://figshare.com/collections/An_international_internet_survey_of_the_experiences_of_1_714_mothers_with_a_late_stillbirth_the_STARS_cohort_study/3640913/1
Dataset

Best iPoster award (First place), Postgraduate summer showcase, University of Manchester
Kowash, H. (Recipient), 2017
Prize: Prize (including medals and awards)
BMA Book Awards 2014 - Highly Commended in Obstetrics & Gynaecology
Crosbie, E. (Recipient) & Heazell, A. (Recipient), 2014
Prize: Prize (including medals and awards)
BMA Book Awards 2017 – Best Book in Obstetrics & Gynaecology
Wan, Y.-L. (Recipient), Crosbie, E. (Recipient), Kitson, S. (Recipient) & Kither, H. (Recipient), 2017
Prize: Prize (including medals and awards)
EMBO Long-Term Fellowship
Wong, F. K. (Recipient), 2016
Prize: Fellowship awarded competitively
Gábor Than Award in Placentology
Forbes, K. (Recipient), Sept 2012
Prize: Prize (including medals and awards)

Podcast on "CHronic hypERtension and L-citRulline studY (CHERRY): an Early-Phase Randomised Controlled Trial in Pregnancy"
Ormesher, L.
12/12/23
1 Media contribution
Press/Media: Research
The simple genetic test for newborns that can prevent profound deafness and save the NHS millions every year
Newman, W., Mcdermott, J., Body, R., Mahaveer, A., Wilson, P., Bruce, I., Booth, N., James, R., Beaman, G., Tricker, K., Turner, M., Harvey, K., Ulph, F. & Macleod, R.
29/03/22
1 item of Media coverage
Press/Media: Research
Pregnant women in Greater Manchester benefit from innovative new app to help monitor blood pressure and glucose from home
Myers, J.
9/12/21
4 items of Media coverage
Press/Media: Research
Life-saving world-first NHS test for pregnant women
Myers, J.
25/08/21
1 item of Media coverage
Press/Media: Research
The Guardian: Most Britons cannot name all parts of the vulva, survey reveals
Reid, F.
30/05/21
1 item of Media coverage
Press/Media: Research

Division of Developmental Biology & Medicine (L5)

Organisation profile

Organisation profile

Collaborations and top research areas from the last five years

Profiles

Research output

Projects

Impacts

Activities

Datasets

Prizes

Press/Media