FBMH Faculty Office

John Aplin, MA, PhD
- john.aplinmanchester.acuk
- Division of Developmental Biology & Medicine (L5) - Professor
- FBMH Faculty Office Administration (L5) - Honorary Professor
Person: Academic
Pauline Baird
- pauline.bairdmanchester.acuk
- FBMH Technical Services (L5) - Research Technician
Person: Technical
Hayley Bennett, BSc, PhD
- FBMH Faculty Office Administration (L5) - Experimental Officer
Person: Technical
Tim Hardingham, BSc, PhD, DSc
- FBMH Faculty Office Administration (L5) - Emeritus Professor
Person: Academic
Claire Alexandra Hart
- FBMH Technical Services (L5) - Scientific Officer
Person: Technical

Cellular signalling protrusions enable dynamic distant contacts in spinal cord neurogenesis
Hawley, J., Lea, R., Biga, V., Papalopulu, N. & Manning, C., 15 Jan 2025, In: Biology Open. 14, 1, bio061765.
Research output: Contribution to journal › Article › peer-review

Open Access
Different mechanisms link gain and loss of kinesin functions to axonal degeneration
Yu-Ting, L., Voelzmann, A., Owens, M., Day, M., Cairns, W., Jones, E., Dajas-bailador, F., McCann, S., Murphy, T., Tortoishell, H., Parkin, J., Bailey, D. M. D., Landgraf, M. & Prokop, A., 1 Jan 2025, Cold Spring Harbor Laboratory Press, (bioRxiv).
Research output: Preprint/Working paper › Preprint
Engineering the glioblastoma microenvironment using TLR7/8 agonist-complexed graphene oxide nanosheets
Stylianou, M., Kisby, T., Despotopoulou, D., Parker, H., Thawley, A., Arashvand, K., Lozano, N., MacDonald, A. S. & Kostarelos, K., 15 Jan 2025, In: Cell Reports Physical Science. 6, 1, 102342.
Research output: Contribution to journal › Article › peer-review

Open Access
Health outcomes in chronic kidney disease patients with cognitive impairment or dementia: a global collaborative analysis
Merlino, L., Rainone, F., Chinnadurai, R., Hernandez, G., Tollitt, J., Battini, G. G., Colombo, P. M., Trivelli, M., Stewart, S., Dunne, R. A. & Kalra, P. A., 25 Jan 2025, In: Clinical Kidney Journal. 18, 1, fae401.
Research output: Contribution to journal › Article › peer-review

Open Access
Proteomic profiling of human plasma and intervertebral disc tissue reveals matrisomal, but not plasma, biomarkers of disc degeneration
Dube, C. T., Gilbert, H., Rabbitte, N., Baird, P., Patel, S., Herrera, J., Baricevic-Jones, I., Unwin, R., Chan, D., Gnanalingham, K., Hoyland, J. & Richardson, S., 26 Jan 2025, (Accepted/In press) In: Arthritis Research and Therapy.
Research output: Contribution to journal › Article › peer-review

1 Active
12 Finished

NIHR Manchester Biomedical Research Centre
Bruce, I. (PI), Lord, G. (CoI), Lennon, R. (CoI), Black, G. (CoI), Wedge, D. (CoI), Morris, A. (CoI), Hussell, T. (CoI), Sharrocks, A. (CoI), Stivaros, S. (CoI), Buch, M. (CoI), Gough, J. (CoI), Kostarelos, K. (CoI), Thistlethwaite, F. (CoI), Kadler, K. (CoI), Barton, A. (CoI), Hyrich, K. (CoI), Mcbeth, J. (CoI), O'Neill, T. (CoI), Vestbo, J. (CoI), Simpson, A. (CoI), Singh, S. (CoI), Smith, J. (CoI), Felton, T. (CoI), Murray, C. (CoI), Griffiths, C. (CoI), Cullum, N. (CoI), Rhodes, L. (CoI), Warren, R. (CoI), Paus, R. (CoI), Dumville, J. (CoI), Viros Usandizaga, A. (CoI), Keavney, B. (CoI), Tomaszewski, M. (CoI), Allan, S. (CoI), Body, R. (CoI), Cartwright, E. (CoI), Heagerty, A. (CoI), Kalra, P. (CoI), Miller, C. (CoI), Rutter, M. (CoI), Smith, C. (CoI), Trafford, A. (CoI), Evans, D. (CoI), Crosbie, E. (CoI), Crosbie, P. (CoI), Harvie, M. (CoI), Howell, S. (CoI), Renehan, A. (CoI), Dive, C. (CoI), Blackhall, F. (CoI), Landers, D. (CoI), Krebs, M. (CoI), Cook, N. (CoI), Clarke, R. (CoI), Taylor, S. (CoI), Jorgensen, C. (CoI), Lorigan, P. (CoI), Jayson, G. (CoI), Valle, J. (CoI), Mccabe, M. (CoI), Armstrong, A. (CoI), Freitas, A. (CoI), Illidge, T. (CoI), Choudhury, A. (CoI), Hoskin, P. (CoI), West, C. (CoI), Van Herk, M. (CoI), Faivre-Finn, C. (CoI), Bristow, R. (CoI), Kirkby, K. (CoI), Birtle, A. (CoI), Mackay, R. (CoI), Radford, J. (CoI), Linton, K. (CoI), Higham, C. (CoI), Munro, K. (CoI), Plack, C. (CoI), Arden Armitage, C. (CoI), Bruce, I. (CoI), Moore, D. (CoI), Saunders, G. (CoI), Stone, M. (CoI), Haddock, G. (CoI), Lewis, S. (CoI), Elliott, R. (CoI), Green, J. (CoI), Lovell, K. (CoI), Morrison, A. (CoI), Shaw, J. (CoI), Bucci, S. (CoI), Ainsworth, J. (CoI), Webb, R. (CoI), Newman, W. (CoI), Banka, S. (CoI), Clayton-Smith, J. (CoI), Payne, K. (CoI), Moldovan, R. (CoI), Wynn, R. (CoI) & Jones, S. (CoI)
1/12/22 → 30/11/27
Project: Research
Impact and recovery from COVID-19 within secure settings for children in custody
Lennox, C. (PI), Carr, M. (CoI), Shaw, J. (CoI) & Walter, F. (CoI)
1/09/21 → 31/08/22
Project: Research
Mass Spec Analysis - 6 Samples
Knight, D. (PI)
23/10/19 → 22/10/20
Project: Other
Manchester Bioelectronics Network
Casson, A. (PI), Grieve, B. (PI), Ozanyan, K. (PI), Blanford, C. (PI), Cartmell, S. (PI), Li, Y. (PI), Ballestrem, C. (PI), Reid, A. (PI), Turner, M. (PI), Wong, L. S. (PI), Yeates, S. (PI), Trimble, E. (PI), Jones, C. (CoI), Scully, P. (CoI), Holmes, M. (CoI), Wimpenny, I. (CoI), Humphrey, B. (CoI), Turner, M. (CoI), Dobson, C. (CoI), Halsall, M. (CoI), Jones, S. (CoI), Echtermeyer, T. (CoI), Wijekoon, J. (CoI), Curry, R. (CoI), Picardo, M. (CoI), Tracey, K. (CoI), Persaud, K. (CoI), Migliorato, M. (CoI), Treves Brown, B. (CoI), Ozanyan, K. (CoI), Wright, P. (CoI), Majewski, L. (CoI), Hodgson, A. (CoI), Dudek, P. (CoI), Gaydecki, P. (CoI), Morgan, P. (CoI), Zhang, H. (CoI), Keavney, B. (CoI), Brenchley, P. (CoI), Fields, R. (CoI), Khan, U. (CoI), Casiraghi, C. (CoI), Blaker, J. (CoI), Saiani, A. (CoI), Vijayaraghavan, A. (CoI), Lu, J. (CoI), Kell, D. (CoI), Donald, A. (PGR student), Ozols, M. (CoI), Derby, B. (CoI), Sharma, J. (CoI), Mills, E. C. (CoI), Mohd Nawi, I. (PGR student), Tandon, B. (PGR student), Read, M. (CoI), Zhu, Q. (CoI), Ren, L. (CoI), Waigh, T. (CoI), Petersen, R. (CoI), Beach, C. (PGR student), Brown, T. (CoI), Thomas, A. (CoI) & Crowe, I. (CoI)
1/02/18 → 31/07/18
Project: Research
Corneal imaging relevant to metabolic disorders.
Aslam, T. (PI)
12/09/17 → 11/09/20
Project: Other

Diagnostics and novel life-saving therapies for aspergillosis
Denning, D. (Participant), Anderson, M. J. (Participant), Moore, C. (Participant), (Participant), Bowyer, P. (Participant), Bromley, M. (Participant), Smith, N. (Participant), (Participant) & (Participant)
Impact: Health impacts
Exploiting an understanding of human visual perception to facilitate human-machine electrocardiogram interpretation of drug-induced long QT syndrome
Alahmadi, A. (Participant), Jay, C. (Participant), Vigo, M. (Participant), Davies, A. (Participant), (Participant), Goodwin, L. (Participant), (Participant), (Participant) & (Participant)
Impact: Technological, Health and wellbeing
Falls prevention amongst older people: Development of effective interventions and improvement of uptake and adherence to services
Todd, C. (Participant), (Participant), Oldham, J. (Participant), (Participant), (Participant), Stanmore, E. (Participant), O'Neill, T. (Participant), Lunt, M. (Participant) & (Participant)
Impact: Health impacts
Re-animating school biology lessons through teaching with living flies
Prokop, A. (Participant) & (Participant)
Impact: Attitudes and behaviours, Awareness and understanding, Society and culture
STORM: Skills Training On Risk Management
(Participant), Appleby, L. (Participant), Morriss, R. (Participant) & (Participant)
Impact: Health impacts, Economic impacts, Societal impacts

5 Membership of committee
3 Organising a conference, workshop, exhibition, performance, inquiry, course etc
2 Other
2 Invited talk

Bloomsbury Summer School
Kozieradzka-Ogunmakin, I. (Chair) & Mcknight, L. (Co-Chair)
1 Jul 2019 → 5 Jul 2019
Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc › Research
United Kingdom Archaeological Sciences Conference
Johnston, E. (Other), Hook, S. (Other), Harvey, V. (Other), Pal Chowdhury, M. (Other), Tollefsen, E. (Other), Buckley, M. (Organiser), Palmer, K. (Other), Brown, T. (Organiser) & Brown, K. (Organiser)
24 Apr 2019 → 26 Apr 2019
Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc › Research
Kings, Courtiers, Creatures and Commoners: three millennia of funerary activity at Saqqara
Mcknight, L. (Co-Chair) & Kozieradzka-Ogunmaki, I. (Co-Chair)
2 Jul 2018 → 6 Jul 2018
Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc › Research
… But what to do with the mummies? Challenges and potential in studying mummified human remains in Egypt and Sudan
Kozieradzka-Ogunmaki, I. (Discussant)
20 Mar 2018
Activity: Talk or presentation › Invited talk › Research
Lives short lived: What can we learn about the life and death of children in Ancient Egypt by studying their physical remains
Kozieradzka-Ogunmaki, I. (Discussant)
10 Feb 2018
Activity: Talk or presentation › Invited talk › Research

Human neuronal extracellular vesicles contain a transcriptional network and tetraspanin-defined subpopulations
Hicks, D. (Creator), Jones, A. C. (Creator), J. Corbett, N. (Creator), Fisher, K. (Creator), Brown, S. P. (Creator), Ashe, M. (Creator) & Hooper, N. (Creator), PRoteomics IDEntifications Database, 8 Sept 2021
https://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD015255
Dataset
Excess S-Adenosylmethionine inhibits methylation via catabolism to adenine
Fustin, J.-M. (Creator), Saer, B. (Contributor), Briggs, P. (Contributor) & Hayes, A. (Contributor), Gene Expression Omnibus - GEO, 23 Sept 2021
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE184525
Dataset
Research data for a study on haemoglobin and heme defences - "EVERREST" study
Brook, A. (Creator), Baynes, G. (Creator), Scargill, J. (Creator), Evangelinos, A. (Creator), Brennan-Richardson, C. (Creator), Dow, F. (Creator), Ginsberg, Y. (Creator), Weissbach, T. (Creator), Brodszki, J. (Creator), Hansson, E. (Creator), Diemert, A. (Creator), Hetcher, K. (Creator), Maksym, K. (Creator), Marlow, N. (Creator), Spencer, R. (Creator), David, A. (Creator), Hansson, S. R. (Creator) & Brownbill, P. (Creator), University of Manchester Figshare, 10 Jun 2024
DOI: 10.48420/25924327, https://figshare.manchester.ac.uk/articles/dataset/Research_data_for_a_study_on_haemoglobin_and_heme_defences_-_EVERREST_study/25924327
Dataset
Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro
Elena, R.-C. (Contributor), Cunningham, C. (Contributor), Miller, J. (Contributor), Martuscelli, L. (Contributor), Aoulad-Ali, S. (Contributor), Rothwell, N. (Contributor), Kielty, C. (Contributor), Allan, S. (Contributor) & Pinteaux, E. (Contributor), figshare , 17 Apr 2017
DOI: 10.6084/m9.figshare.c.3743330.v1, https://figshare.com/collections/Interleukin-1_primes_human_mesenchymal_stem_cells_towards_an_anti-inflammatory_and_pro-trophic_phenotype_in_vitro/3743330/1
Dataset
An RNAi-mediated screen identifies novel targets for next-generation antiepileptic drugs based on increased expression of the homeostatic regulator pumilio
Lin, W.-H. (Contributor), He, M. (Contributor), Fan, Y. N. (Contributor) & Baines, R. (Contributor), figshare , 4 Jun 2018
DOI: 10.6084/m9.figshare.6213614.v2, https://figshare.com/articles/An_RNAi-mediated_screen_identifies_novel_targets_for_next-generation_antiepileptic_drugs_based_on_increased_expression_of_the_homeostatic_regulator_pumilio/6213614/2 and one more link, https://ndownloader.figshare.com/files/11823593 (show fewer)
Dataset

4Cite: Publications showcase "Refractory RA"
Kearsley-Fleet, L. (Recipient), Oct 2018
Prize: Other distinction
4Cite: Publications showcase "Systemic JIA"
Kearsley-Fleet, L. (Recipient), May 2019
Prize: Other distinction
Group award: for Outstanding contribution to patient and public involvement and engagement (Faculty of biology, Medicine and Health).
Sturrock, A. (Recipient), 17 Jul 2018
Prize: Prize (including medals and awards)
Social responsibility fund
Sturrock, A. (Recipient), 1 Dec 2019
Prize: Prize (including medals and awards)
Teaching Excellence Award 2023 (team - Winner)
Weise, N. (Recipient), Oakley, M. (Recipient), Rotherham, B. (Recipient), Dewsnip, H. (Recipient), Tickell, F. (Recipient), Salins, C. (Recipient), Beare, P. (Recipient) & Shay, S. (Recipient), 27 Sept 2023
Prize: Prize (including medals and awards)

VARIOUS NATIONAL MEDIA: Manchester researchers lead programme to assess instant testing for COVID-19
Body, R., Dark, P. & Lord, G.
24/06/20
2 items of Media coverage, 3 Media contributions
Press/Media: Research
VARIOUS LOCAL AND NATIONAL MEDIA: Greater Manchester coronavirus response
Bruce, I. & Lord, G.
31/03/20
1 item of Media coverage
Press/Media: Research
MANCHESTER EVENING NEWS: University scientists join forces with Manchester hospitals in fight against coronavirus
Bruce, I. & Lord, G.
30/03/20
1 item of Media coverage
Press/Media: Research
Derby Museums' mummies travel to Manchester
Mcknight, L., Kozieradzka-Ogunmaki, I. & Price, C.
16/09/19
1 Media contribution
Press/Media: Research
DERBY MUSEUMS’ MUMMIES TRAVEL TO MANCHESTER FOR STATE-OF-THE-ART SCANS
Kozieradzka-Ogunmaki, I., Mcknight, L. & Price, C.
20/05/19
1 item of Media coverage
Press/Media: Research

Biological Mass Spectrometry (BioMS) Facility
Knight, D. (Platform Lead), Warwood, S. (Senior Technical Specialist), Selley, J. (Technical Specialist), Taylor, G. (Technical Specialist), Fullwood, P. (Technical Specialist), Keevill, E.-J. (Senior Technician) & Allsey, J. (Technician)
FBMH Platform Sciences, Enabling Technologies & Infrastructure
Facility/equipment: Facility

FBMH Faculty Office

Collaborations and top research areas from the last five years

Profiles

Research output

Projects

Impacts

Activities

Datasets

Prizes

Press/Media

Equipment