FBMH Faculty Office Administration

John Aplin, MA, PhD
- john.aplinmanchester.acuk
- Division of Developmental Biology & Medicine (L5) - Professor
- FBMH Faculty Office Administration (L5) - Honorary Professor
Person: Academic
Pauline Baird
- pauline.bairdmanchester.acuk
- FBMH Technical Services (L5) - Research Technician
Person: Technical
Graham Barnes
- G.R.Barnesmanchester.acuk
- FBMH Faculty Office Administration (L5) - Emeritus Professor
Person: Academic
B.H Chan, BSc
- FBMH Technical Services (L5) - Research Technician
Person: Technical
Laura Hand
Person

Molecular genotype-phenotype correlation in ACTB- and ACTG1-related non-muscle actinopathies
Di Donato, N., Thom, A., Rump, A., Greve, J. N., Cadiñanos, J., Calabro, S., Cathey, S., Chung, B. K., Cope, H., Costales, M., Cuvertino, S., Dinkel, P., Erripi, K., Fry, A. E., Garavelli, L., Hoffjan, S., Janzarik, W. G., Kreimer, I., Mancini, G. & Marin-Reina, P. & 22 others, Meinhardt, A., Niehaus, I., Pilz, D. T., Ricca, I., Simarro, F. S., Schrock, E., Marquardt, A., Taft, M. H., Tezcan, K., Thunström, S., Verhagen, J., Verloes, A., Wollnik, B., Krawitz, P. M., Hsieh, T.-C., Seifert, M., Heide, M., Lawrence, C., Roberts, N., Manstein, D. J., Woolf, A. & Banka, S., 12 Jan 2026, (E-pub ahead of print) In: American Journal of Human Genetics.
Research output: Contribution to journal › Article › peer-review

Open Access
Spatial-Spectral Deep Learning for Prostate Cancer Tissue Classification in Infrared Spectroscopy
O'Leary, L., Ferguson, D., Hart, C. A., Brown, M., Oliveira, P., Clarke, N., Sachdeva, A., Gardner, P. & Yin, H., 14 Jan 2026, (Accepted/In press) In: Analytical Chemistry.
Research output: Contribution to journal › Article › peer-review
Ablation of Bronchiolar Epithelial Cell Clock Gene, Rev-erbα, Disrupts Circadian Rhythmicity in Airway Hyperresponsiveness by Introducing Transcriptomic Changes
Chakraborty, A., Cain, J., Maidstone, R., Deugi, V., Bechtold, D., Gibbs, J. & Durrington, H., 2025, American Journal of Respiratory Critical Care Medicine. Vol. 211. A7354
Research output: Chapter in Book/Conference proceeding › Conference contribution › peer-review

Open Access
Acute-onset axonal neuropathy following infection in children with biallelic<i> RCC1</i> variants: a case series
Harkness, J. R., Mcdermott, J. H., Marsden, S., Jamieson, P., Metcalfe, K. A., Khan, N., Macken, W. L., Pitceathly, R. D. S., Record, C. J., Maroofian, R., Kleopa, K., Christodoulou, K., Sabir, A., Islam, L., Santra, S., Durmusalioglu, E. A., Atik, T., Isik, E., Cogulu, O. & Urquhart, J. E. & 43 others, Beaman, G. M., Demain, L. A., Jackson, A., Blakes, A. J. M., Byers, H. J., Bennett, H., Lin, W.-H., Adamson, A., Patel, S., Yue, W. W., Taylor, R. W., Reunert, J., Marquardt, T., Buchert, R., Haack, T., Losch, H., Ryba, L., Lassuthova, P., Valkovicova, R., Haberlova, J., Lauerova, B., Trusikova, E., Polavarapu, K., Kilicarslan, O. A., Lochmuller, H., Zamani, M., Chamanrou, N., Shariati, G., Sadeghian, S., Azizimalamiri, R., Maddirevula, S., Almuhaizea, M., Alkuraya, F. S., Horvath, R., Gungor, S., Manzur, A., Munot, P., Matthews, R., Banka, S., Reilly, M. M., Bennett, D., O'keefe, R. T. & Newman, W. G., Aug 2025, In: Lancet Neurology. 24, 8, p. 667-680 14 p.
Research output: Contribution to journal › Article › peer-review
Acute-onset axonal neuropathy following infection in children with biallelic RCC1 variants: a case series
Harkness, J. R., McDermott, J. H., Marsden, S., Jamieson, P., Metcalfe, K. A., Khan, N., Macken, W. L., Pitceathly, R. D. S., Record, C. J., Maroofian, R., Kleopa, K., Christodoulou, K., Sabir, A., Islam, L., Santra, S., Durmusalioglu, E. A., Atik, T., Isik, E., Cogulu, O. & Urquhart, J. E. & 43 others, Beaman, G. M., Demain, L. A., Jackson, A., Blakes, A. J. M., Byers, H. J., Bennett, H., Lin, W. H., Adamson, A., Patel, S., Yue, W. W., Taylor, R. W., Reunert, J., Marquardt, T., Buchert, R., Haack, T., Losch, H., Ryba, L., Lassuthova, P., Valkovičová, R., Haberlová, J., Lauerová, B., Trúsiková, E., Polavarapu, K., Kilicarslan, O. A., Lochmüller, H., Zamani, M., Chamanrou, N., Shariati, G., Sadeghian, S., Azizimalamiri, R., Maddirevula, S., AlMuhaizea, M., Alkuraya, F. S., Horvath, R., Gungor, S., Manzur, A., Munot, P., Matthews, R., Banka, S., Reilly, M. M., Bennett, D., O'Keefe, R. T. & Newman, W. G., Aug 2025, In: The Lancet Neurology. 24, 8, p. 667-680 14 p.
Research output: Contribution to journal › Article › peer-review

3 Active
9 Finished

How tensins transform focal adhesions into fibrillar adhesions and phase separate to form new adhesion signalling hubs
Ballestrem, C. (PI) & Garrod, D. (CoI)
1/04/24 → 31/03/27
Project: Research
How the actin-desmosome crossalk regulates desmosome adhesion
Ballestrem, C. (PI) & Garrod, D. (CoI)
1/05/23 → 30/04/26
Project: Research
NIHR Manchester Biomedical Research Centre
Bruce, I. (PI), Lord, G. (CoI), Lennon, R. (CoI), Black, G. (CoI), Wedge, D. (CoI), Morris, A. (CoI), Hussell, T. (CoI), Sharrocks, A. (CoI), Stivaros, S. (CoI), Buch, M. (CoI), Gough, J. (CoI), Kostarelos, K. (CoI), Thistlethwaite, F. (CoI), Kadler, K. (CoI), Barton, A. (CoI), Hyrich, K. (CoI), Mcbeth, J. (CoI), O'Neill, T. (CoI), Vestbo, J. (CoI), Simpson, A. (CoI), Singh, S. (CoI), Smith, J. (CoI), Felton, T. (CoI), Murray, C. (CoI), Griffiths, C. (CoI), Cullum, N. (CoI), Rhodes, L. (CoI), Warren, R. (CoI), Paus, R. (CoI), Dumville, J. (CoI), Viros Usandizaga, A. (CoI), Keavney, B. (CoI), Tomaszewski, M. (CoI), Allan, S. (CoI), Body, R. (CoI), Cartwright, E. (CoI), Heagerty, A. (CoI), Kalra, P. (CoI), Miller, C. (CoI), Rutter, M. (CoI), Smith, C. (CoI), Trafford, A. (CoI), Evans, D. (CoI), Crosbie, E. (CoI), Crosbie, P. (CoI), Harvie, M. (CoI), Howell, S. (CoI), Renehan, A. (CoI), Dive, C. (CoI), Blackhall, F. (CoI), Landers, D. (CoI), Krebs, M. (CoI), Cook, N. (CoI), Clarke, R. (CoI), Taylor, S. (CoI), Jorgensen, C. (CoI), Lorigan, P. (CoI), Jayson, G. (CoI), Valle, J. (CoI), Mccabe, M. (CoI), Armstrong, A. (CoI), Freitas, A. (CoI), Illidge, T. (CoI), Choudhury, A. (CoI), Hoskin, P. (CoI), West, C. (CoI), Van Herk, M. (CoI), Faivre-Finn, C. (CoI), Bristow, R. (CoI), Kirkby, K. (CoI), Birtle, A. (CoI), Mackay, R. (CoI), Radford, J. (CoI), Linton, K. (CoI), Higham, C. (CoI), Munro, K. (CoI), Plack, C. (CoI), Arden Armitage, C. (CoI), Bruce, I. (CoI), Moore, D. (CoI), Saunders, G. (CoI), Stone, M. (CoI), Haddock, G. (CoI), Lewis, S. (CoI), Elliott, R. (CoI), Green, J. (CoI), Lovell, K. (CoI), Morrison, A. (CoI), Shaw, J. (CoI), Bucci, S. (CoI), Ainsworth, J. (CoI), Webb, R. (CoI), Newman, W. (CoI), Banka, S. (CoI), Clayton-Smith, J. (CoI), Payne, K. (CoI), Moldovan, R. (CoI), Wynn, R. (CoI) & Jones, S. (CoI)
1/12/22 → 30/11/27
Project: Research
Manchester Bioelectronics Network
Casson, A. (PI), Grieve, B. (PI), Ozanyan, K. (PI), Blanford, C. (PI), Cartmell, S. (PI), Li, Y. (PI), Ballestrem, C. (PI), Reid, A. (PI), Turner, M. (PI), Wong, L. S. (PI), Yeates, S. (PI), Trimble, E. (PI), Jones, C. (CoI), Scully, P. (CoI), Holmes, M. (CoI), Wimpenny, I. (CoI), Humphrey, B. (CoI), Turner, M. (CoI), Dobson, C. (CoI), Halsall, M. (CoI), Jones, S. (CoI), Echtermeyer, T. (CoI), Wijekoon, J. (CoI), Curry, R. (CoI), Picardo, M. (CoI), Tracey, K. (CoI), Persaud, K. (CoI), Migliorato, M. (CoI), Treves Brown, B. (CoI), Ozanyan, K. (CoI), Wright, P. (CoI), Majewski, L. (CoI), Hodgson, A. (CoI), Dudek, P. (CoI), Gaydecki, P. (CoI), Morgan, P. (CoI), Zhang, H. (CoI), Keavney, B. (CoI), Brenchley, P. (CoI), Fields, R. (CoI), Khan, U. (CoI), Casiraghi, C. (CoI), Blaker, J. (CoI), Miller, A. (CoI), Vijayaraghavan, A. (CoI), Lu, J. (CoI), Kell, D. (CoI), Donald, A. (PGR student), Ozols, M. (CoI), Derby, B. (CoI), Sharma, J. (CoI), Mills, E. C. (CoI), Mohd Nawi, I. (PGR student), Tandon, B. (PGR student), Read, M. (CoI), Zhu, Q. (CoI), Ren, L. (CoI), Waigh, T. (CoI), Petersen, R. (CoI), Beach, C. (PGR student), Brown, T. (CoI), Thomas, A. (CoI) & Crowe, I. (CoI)
1/02/18 → 31/07/18
Project: Research
National Learning Disabilities Mortality Review Scoping Project
Appleby, L. (PI), Kapur, N. (CoI), Rodway, C. (CoI), Shaw, J. (CoI) & Windfuhr, K. (CoI)
11/08/14 → 10/11/14
Project: Research

Diagnostics and novel life-saving therapies for aspergillosis
Denning, D. (Participant), Anderson, M. J. (Participant), Moore, C. (Participant), Warn, P. (Participant), Bowyer, P. (Participant), Bromley, M. (Participant), Smith, N. (Participant), Howard, S. (Participant) & Niven, R. (Participant)
Impact: Health impacts
Fibrillin-rich microfibrils and efficacy of anti-ageing cosmetics
Griffiths, C. (Participant), Watson, R. (Participant), Kielty, C. (Participant) & Shuttleworth, A. (Participant)
Impact: Health impacts
Home treatment for female urinary incontinence
Oldham, J. (Participant)
Impact: Health and wellbeing
PARENTING+: Using media-based dissemination of intervention to improve parenting and prevent dysfunction
Calam, R. (Participant) & Sanders, M. (Participant)
Impact: Health impacts, Societal impacts
Re-animating school biology lessons through teaching with living flies
Prokop, A. (Participant) & Patel, S. (Participant)
Impact: Attitudes and behaviours, Awareness and understanding, Society and culture

10 Invited talk
7 Organising a conference, workshop, exhibition, performance, inquiry, course etc
6 Participating in a conference, workshop, exhibition, performance, inquiry, course etc
4 Other
More

Biomolecular Analysis – GAG array work
Flannelly, J. (Academic founder), Jowitt, T. (Academic founder) & Murphy, L. (Academic founder)
1 May 2024 → 30 Jun 2024
Activity: Consultancy, spin-outs, CPD & licensing › Consultancy & Services › Research
Biomolecular analysis - GAG array work
Flannelly, J. (Other), Jowitt, T. (Other) & Murphy, L. (Other)
22 Apr 2024 → 24 Jun 2024
Activity: Internal positions, career professional development, other peer review and other › Other › Research
Oldham Library Visit
Weise, N. (Co-Organiser), Shareef, A. S. (Participant) & Vekaria, K. (Participant)
3 Sept 2022
Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc › Research

File
Owlstone Medical: Working with cat2 fungal pathogens
Thomson, D. (Consultant)
Oct 2020
Activity: Consultancy, spin-outs, CPD & licensing › Consultancy & Services › Research
Bloomsbury Summer School
Kozieradzka-Ogunmakin, I. (Chair) & Mcknight, L. (Co-Chair)
1 Jul 2019 → 5 Jul 2019
Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc › Research

Human neuronal extracellular vesicles contain a transcriptional network and tetraspanin-defined subpopulations
Hicks, D. (Creator), Jones, A. C. (Creator), J. Corbett, N. (Creator), Fisher, K. (Creator), Brown, S. P. (Creator), Ashe, M. (Creator) & Hooper, N. (Creator), PRoteomics IDEntifications Database, 8 Sept 2021
https://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD015255
Dataset
Excess S-Adenosylmethionine inhibits methylation via catabolism to adenine
Fustin, J.-M. (Creator), Saer, B. (Contributor), Briggs, P. (Contributor) & Hayes, A. (Contributor), Gene Expression Omnibus - GEO, 23 Sept 2021
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE184525
Dataset
In Silico analysis of human ACTB known variants and their effects on function, including ACGM clasifications and alternitave splicing analysis. Appendix 3 of Andrew J Thom's PhD thesis
Thom, A. (Creator), University of Manchester Figshare, 22 Jan 2025
DOI: 10.48420/25042589.v1, https://figshare.manchester.ac.uk/articles/dataset/In_Silico_analysis_of_human_ACTB_known_variants_and_their_effects_on_function_including_ACGM_clasifications_and_alternitave_splicing_analysis_Appendix_3_of_Andrew_J_Thom_s_PhD_thesis/25042589/1
Dataset
Human patient cohort data of ACTB variants comprising of both published and unpublished data. The data contains genomic and phenotype iformation on over 140 patients worldwide. It is also Appendix 2 of Andrew J Thom's thesis.
Thom, A. (Creator), University of Manchester Figshare, 22 Jan 2025
DOI: 10.48420/25042583.v1, https://figshare.manchester.ac.uk/articles/dataset/Human_patient_cohort_data_of_ACTB_variants_comprising_of_both_published_and_unpublished_data_The_data_contains_genomic_and_phenotype_iformation_on_over_140_patients_worldwide_It_is_also_Appendix_2_of_Andrew_J_Thom_s_thesis_/25042583/1
Dataset
An RNAi-mediated screen identifies novel targets for next-generation antiepileptic drugs based on increased expression of the homeostatic regulator pumilio
Lin, W.-H. (Contributor), He, M. (Contributor), Fan, Y. N. (Contributor) & Baines, R. (Contributor), figshare , 4 Jun 2018
DOI: 10.6084/m9.figshare.6213614.v2, https://figshare.com/articles/An_RNAi-mediated_screen_identifies_novel_targets_for_next-generation_antiepileptic_drugs_based_on_increased_expression_of_the_homeostatic_regulator_pumilio/6213614/2 and one more link, https://ndownloader.figshare.com/files/11823593 (show fewer)
Dataset

4Cite: Publications showcase "Refractory RA"
Kearsley-Fleet, L. (Recipient), Oct 2018
Prize: Other distinction
4Cite: Publications showcase "Systemic JIA"
Kearsley-Fleet, L. (Recipient), May 2019
Prize: Other distinction
Dr Alex Carmichael Award
Robinson, A. (Recipient), 2016
Prize: Prize (including medals and awards)
ILM Level 5 Award in Leadership and Management
Kozieradzka-Ogunmaki, I. (Recipient), 21 Apr 2017
Prize: Prize (including medals and awards)
Marie Skłodowska-Curie Research Fellowship
Kozieradzka-Ogunmaki, I. (Recipient), 21 Nov 2016
Prize: Fellowship awarded competitively

GOOD MORNING KENYA: Kenya - UK Health Alliance
Lord, G.
15/03/22
1 Media contribution
Press/Media: Expert comment
commentary on being an observer on week 1 of COP26 Glasgow
Dubicka, B.
8/11/21
1 Media contribution
Press/Media: Blogs and social media
Improvements in Diabetic Neuropathy and Nephropathy After Bariatric Surgery: a Prospective Cohort Study
Syed, A., Adam, S., Soran, H., Kalra, P., Malik, R. & Donn, R.
30/10/20
1 item of Media coverage
Press/Media: Research
VARIOUS NATIONAL MEDIA: Manchester researchers lead programme to assess instant testing for COVID-19
Body, R., Dark, P. & Lord, G.
24/06/20
2 items of Media coverage, 3 Media contributions
Press/Media: Research
VARIOUS LOCAL AND NATIONAL MEDIA: Greater Manchester coronavirus response
Bruce, I. & Lord, G.
31/03/20
1 item of Media coverage
Press/Media: Research

Bio-imaging and Histology
March, P. (Expert Technical Specialist), Haley, M. (Senior Technical Specialist), Bagnall, J. (Senior Technical Specialist), Marsden, S. (Senior Technical Specialist), Verdes, M. (Technical Specialist), Campbell, N. (Senior Technician) & Khan, M. A. (Senior Technical Specialist)
Facility/equipment: Facility
Biological Mass Spectrometry (BioMS) Facility
Knight, D. (Core Facility Lead), Warwood, S. (Senior Technical Specialist), Selley, J. (Technical Specialist), Taylor, G. (Technical Specialist), Fullwood, P. (Technical Specialist), Keevill, E.-J. (Senior Technician) & Allsey, J. (Technician)
FBMH Platform Sciences, Enabling Technologies & Infrastructure
Facility/equipment: Facility
Clinical and Pre-Clinical Imaging
Ogden, D. (Other), Little, R. (Senior Technical Specialist), Leverton, B. (Technician), Forster, D. (Other) & Foster, F. (Other)
Faculty of Biology, Medicine and Health
Facility/equipment: Facility
Electron Microscopy
Mironov, A. (Core Facility Lead), Collins, R. (Core Facility Lead), Forbes, S. (Technical Specialist), Baldock, C. (Academic lead), Foster, F. (Other) & Becker, M. (Other)
FBMH Platform Sciences, Enabling Technologies & Infrastructure
Facility/equipment: Facility
Flow Cytometry
Howell, G. (Core Facility Lead), Chapman, D. (Technical Specialist), Baron, J. (Technical Specialist), Mallender, R. (Academic lead), Konkel, J. (Academic lead) & Foster, F. (Other)
FBMH Platform Sciences, Enabling Technologies & Infrastructure
Facility/equipment: Facility

FBMH Faculty Office Administration

Collaborations and top research areas from the last five years

Profiles

Research output

Projects

Impacts

Activities

Datasets

Prizes

Press/Media

Equipment