Research output per year
Research output per year
Organisation profile
Organisation profile
The School of Medical Sciences is currently led by Professor Tony Heagerty.
As well as being active across many of the Faculty's research domains, we engage in a diverse range of activities within our divisions:
- Division of Cancer Sciences
- Division of Cardiovascular Sciences
- Division of Dentistry
- Division of Developmental Biology and Medicine
- Division of Diabetes, Endocrinology and Gastroenterology
- Division of Medical Education
We are a world-leading integrated medical sciences research and teaching school, and the largest provider of healthcare graduates to the NHS in north-west England.
We host the largest medical school in the UK with around 3,100 undergraduates, 1,200 postgraduates and 2,000 staff. We also have the highest-ranking dental school in the north of England.
Our research
The School undertakes internationally recognised research spanning bench-side research science in areas from cardiology and developmental biology to clinical trials.
Strong funding links with major UK charities such as British Heart Foundation and Cancer Research UK support our research, as well as UK Research and Innovation (UKRI). Our annual research income is around £30 million.
We have one of the University’s Research Beacons in Cancer Sciences represented through our Division of Cancer Sciences, and through our partnership with the Manchester Cancer Research Centre.
Our teaching
The School is home to two five-year undergraduate degrees, MBChB Medicine and BDS Dentistry. The MBChB Medicine (Graduate Entry) course will have its first intake in 2024. An integrated degree course for every medical student will be available from 2026. We also offer a considerable range of postgraduate courses.
We have international curriculum licencing agreements in Egypt and the Middle East, alongside a long-standing partnership with the International Medical School.
Find out more
Visit our Faculty website to learn more about the School of Medical Sciences
Contact us
Email: [email protected]
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Sabu Abraham, MSc, PhD
- Division of Cardiovascular Sciences (L5) - Lecturer in Cardiovascular Medicine
Person: Academic
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Adedamola Adetiba
- Centre for the History of Science, Technology and Medicine (CHSTM) - Research Fellow
Person: Academic
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10-year multimorbidity patterns among people with and without rheumatic and musculoskeletal diseases: an observational cohort study using linked electronic health records from Wales, UK
Jalali-najafabadi, F., Bailey, R., Lyons, J., Akbari, A., Dhafari, T. B., Azadbakht, N., Rafferty, J., Watkins, A., Martin, G. P., Bowes, J., Lyons, R. A., Barton, A. & Peek, N., 19 Jun 2024, In: BMJ Open. 14, 6, e079169.Research output: Contribution to journal › Article › peer-review
Open Access -
211 Systemic inflammation leads to neuronal loss and exacerbates behavioural deficits in a mouse model of MPS IIIA
Mandolfo, O., Parker, H., Aguado, È., Learmonth, Y. I., Liao, A., O'Leary, C., Ellison, S. M., Taylor, J., Wood, S. R., Holley, R., Boutin, H. & Bigger, B., Feb 2024, In: Molecular genetics and metabolism. 141, 2, 1 p.Research output: Contribution to journal › Meeting Abstract › peer-review
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25-hydroxycholesterol dysregulates brain endothelial cell function and exacerbates cerebral haemorrhage
Tapia, V. S., Withers, S., Zhou, R., Bennington, A., Hedley, F., El Khouja, A., Luka, N., Massimo, M., Crilly, S., Long, K., Lawrence, C. B. & Kasher, P., 10 May 2024, Cold Spring Harbor Laboratory Press, (bioRxiv).Research output: Preprint/Working paper › Preprint
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3-methyl-phenanthrene (3-MP) disrupts the electrical and contractile activity of the heart of the polar fish, navaga cod (Eleginus nawaga)
Filatova, T. S., Kuzmin, V. S., Dzhumaniiazova, I., Pustovit, O. B., Abramochkin, D. V. & Shiels, H. A., 19 Apr 2024, (E-pub ahead of print) In: Chemosphere. 142089.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Downloads (Pure) -
754: An audit of a compensation technique for cord and brainstem doses in head and neck reirradiation
Nash, D., Muscat, S., Thiong'o, C., Osorio, E. V. & Palmer, A., 3 May 2024, In: Radiotherapy and Oncology. 194, Supplement 1, p. S3798-S3801Research output: Contribution to journal › Conference article › peer-review
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Evaluation of the clinical impact and cost-utility of a comprehensive digital diabetes self-management platform
Rutter, M. (PI), Kontopantelis, E. (CoI), Brooks, J. (CoI), Rogers, G. (CoI) & Allen, T. (CoI)
1/06/24 → 31/10/26
Project: Research
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Mask-Wearing in Semi-Colonial China: Everyday Medical Device and Its Applications to Governing Chinese, 1912-1949
Zhang, M. (PI), Kirk, R. (CoI) & Homei, A. (CoI)
1/11/23 → 31/10/26
Project: Research
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Defining the causal role of altered cell-type-specific DNA methylation in Diabetic Kidney Disease
Lay, A. (PI)
1/10/23 → 30/09/26
Project: Research
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Oxford Nanopore PromethION
Ellingford, J. (PI), Adamson, A. (CoI), Banka, S. (CoI), Black, G. (CoI), Brockhurst, M. (CoI), Coyte, K. (CoI), Gifford, D. (CoI), Hayes, A. (CoI), Hubbard, S. (CoI), Lagator, M. (CoI), Mcdermott, J. (CoI), Newman, W. (CoI), Sergouniotis, P. (CoI), Sharrocks, A. (CoI) & Wedge, D. (CoI)
31/07/23 → 30/07/26
Project: Research
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The Nucleus Reuniens as a key control point for effects of light on learning and memory
Brown, T. (PI), Gigg, J. (CoI) & Lucas, R. (CoI)
1/05/23 → 30/04/26
Project: Research
Impacts
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Access to more effective therapies in Non-Hodgkin Lymphoma
Illidge, T. (Corresponding participant), Radford, J. (Participant) & Honeychurch, J. (Participant)
Impact: Health and wellbeing, Economic
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Adjuvant therapy in melanoma adopted as standard of care
Lorigan, P. (Participant)
Impact: Health and wellbeing
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Allowing easier identification of signs of malnutrition using the paperweight armband
Mclaughlin, J. (Corresponding participant)
Impact: Economic, Health and wellbeing
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A new international lighting standard that meets our biological needs
Lucas, R. (Participant), Brown, T. (Participant), Allen, A. (Participant) & (Participant)
Impact: Technological impacts, Health and wellbeing, Society and culture, Economic
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A new international measurement standard and guidelines for healthy lighting
Timothy Brown (Participant), Robert Lucas (Participant) & Annette Allen (Participant)
Impact: Society and culture, Policy, Economic, Awareness and understanding, Health and wellbeing
Activities
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Caldwell Memorial Lecture "Using antibiotics sustainably"
Thompson, W. (Invited speaker)
6 Dec 2024Activity: Talk or presentation › Invited talk › Teaching and Research
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Being Human Festival: Fossil Stories
Bonea, A. (Organiser)
16 Oct 2024 → 14 Nov 2024Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc › Teaching and Research
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Post-Bariatric Surgery - Follow Up and Management
Syed, A. (Invited speaker)
20 Sept 2024Activity: Talk or presentation › Invited talk › Teaching
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Antibiotics are supposed to help, aren’t they?: The risks and benefits of antibiotics in dentistry
Thompson, W. (Speaker)
13 Sept 2024Activity: Talk or presentation › Invited talk › Teaching and Research
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Climate Change and the Beginning of the Crisis Decades
Naylor, R. (Co-Chair), Honeybun-Arnolda, E. (Co-Chair) & Morgan, R. (Co-Organiser)
30 Aug 2024Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc › Research
Datasets
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Human Embryonic Multi-tissue ChIP-seq (Manchester)
Gerrard, D. (Creator), Hanley, N. (Owner) & Jennings, R. (Data Manager), The European Genome-phenome Archive, 2019
https://ega-archive.org/datasets/EGAD00001004335
Dataset
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RNA methylation-dependent RNA processing controls the speed of the circadian clock
Fustin, J. (Creator), Kyoto University, 7 Nov 2013
DOI: 10.1016/j.cell.2013.10.026, https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE48037
Dataset
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Proteomic analysis of an induced pluripotent stem cell model reveals strategies to treat Juvenile Myelomonocytic Leukaemia
Whetton, A. (Creator), PRoteomics IDEntifications Database, 2019
https://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD014708
Dataset
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Identification of protein-protein interactions involving the eIF4E binding proteins Caf20p and Eap1p on yeast via affinity purification and LC-MSMS.
Castelli, L. M. (Creator), Talavera, D. (Creator), Kershaw, C. J. (Creator), Mohammad-Qureshi, S. S. (Creator), Costello, J. L. (Creator), Rowe, W. (Creator), Sims, P. F. G. (Creator), Grant, C. (Creator), Hubbard, S. (Creator), Ashe, M. (Creator) & Pavitt, G. (Creator), ProteomeXchange, 29 Jun 2016
DOI: 10.6019/PXD001407, https://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD001407
Dataset
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Excess S-Adenosylmethionine inhibits methylation via catabolism to adenine
Fustin, J. (Creator), Saer, B. (Contributor), Briggs, P. (Contributor) & Hayes, A. (Contributor), Gene Expression Omnibus - GEO, 23 Sept 2021
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE184525
Dataset
Prizes
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1st Annual Brady Award for Resident Research, Joint Oncology Program. University of Toronto, Toronto, Ontario
Bristow, R. (Recipient), 1996
Prize: Prize (including medals and awards)
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2018 Outstanding Clinical Contribution to The Christie NHS Foundation Trust
Hughes, A. (Recipient), May 2018
Prize: Prize (including medals and awards)
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2019 John Simon Guggenheim Memorial Foundation Fellowship
Burney, Ian (Recipient), 2019
Prize: Election to learned society
Press/Media
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Water fluoridation ‘less effective’ than in the past –study
O'Malley, L., Glenny, A.-M. & Walsh, T.
3/10/24 → 4/10/24
4 Media contributions
Press/Media: Research
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New groundbreaking chest pain diagnosis test device for paramedics across the Northwest
19/07/24
1 item of Media coverage
Press/Media: Research
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Risk of Cardiovascular Side Effects with Newer Hormone Therapies
Sachdeva, A. & Clarke, N.
2/07/24
1 item of Media coverage
Press/Media: Research
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Meta-Analysis Evaluates Cardiovascular Risks of AR Inhibitors in Prostate Cancer
Sachdeva, A. & El-Taji, O.
28/06/24
1 item of Media coverage
Press/Media: Research
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New breakthrough drug for leukaemia trialled at The Christie
24/04/24
1 item of Media coverage
Press/Media: Research
Student theses
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3D anatomical modelling of the human cardiac conduction system
Atkinson, A. (Author), Dobrzynski, H. (Supervisor) & Boyett, M. (Supervisor), 3 Jan 2015Student thesis: Master of Philosophy
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3-Dimensional SEM Studies of the Sarcoplasmic Reticulum in Chicken Hearts
Newman, B. (Author), Shiels, H. (Supervisor) & Codd, J. (Supervisor), 31 Dec 2016Student thesis: Master of Philosophy
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3D Printed Denture Materials: Key Aspects of their Physico-Mechanical and Biological Properties
Altarazi, A. (Author), Haider, J. (Supervisor), Devlin, H. (Supervisor) & Silikas, N. (Supervisor), 31 Dec 2023Student thesis: Phd
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3D-Printing for Radiotherapy Using Flexible Filament Materials
Burnley, J. (Author), Budgell, G. (Supervisor), 1 Aug 2022Student thesis: Unknown
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A 3D Printed Cardiac Phantom for Nuclear Medicine Imaging
Jasmat, L. (Author), Mackay, R. (Supervisor), 1 Aug 2023Student thesis: Unknown
File