Personal profile
Biography
PhD on Photoelectron Spectroscopy of Small Metallic Particles
UMIST, 1996
BSc in Chemistry
UMIST, 1988
Certificate in Mathematics
Open University, 2010
Certificate in Semantic Web Technologies
OpenHPI, 2013
Director of SurfaceSpectra Ltd.
Director of the International Society for Clinical Spectroscopy
Honorary Lecturer in Cheminformatics
Honorary Lecturer in Analytical Science
Academic Visitor at Imperial College London
Other research
Special Interest Groups
Research interests
My research interests lie in data reduction, working mainly with the results from ToF-SIMS (time of flight secondary ion mass spectrometry) and IR (infra red spectroscopy) experiments in cell chemistry. Chemometric and cheminformatic approaches are applied to spectra, 2D chemical images and 3D chemical hypercubes to understand the complex chemistries involved in cell structure, metabolism and drug interaction. Work carried out in parallel aims to develop visualisation tools for chemists and biologists working in this area.
My group
- Analytical Science
Education/Academic qualification
Certificate in Semantic Web Technologies, Hasso Plattner Institute
1 Feb 2013 → 1 Jun 2013
Award Date: 1 Jun 2013
Certificate in Mathematics, The Open University
1 Oct 2008 → 1 Oct 2010
Award Date: 1 Oct 2010
Doctor of Philosophy, Photoelectron Spectroscopy of Small Metallic Particles, UMIST
1 Oct 1988 → 4 Jul 1996
Award Date: 4 Jul 1996
Bachelor of Science, Chemistry, UMIST
3 Oct 1985 → 4 Jul 1988
Award Date: 4 Jul 1988
External positions
Academic Visitor, Imperial College London
1 Jan 2017 → 30 Jun 2017
Director, The International Society for Clinical Spectroscopy
30 Jun 2015 → …
Director, SurfaceSpectra Ltd
Feb 1997 → …
Areas of expertise
- QD Chemistry
- Analytical Chemistry
- Chemometrics
- Cheminformatics
- Spectroscopy
- Spectrometry
- QA75 Electronic computers. Computer science
Research Beacons, Institutes and Platforms
- Cancer
- Biotechnology
- Digital Futures
- Institute for Data Science and AI
- Christabel Pankhurst Institute
- Manchester Institute of Biotechnology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 7 Affordable and Clean Energy
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SDG 9 Industry, Innovation, and Infrastructure
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SDG 12 Responsible Consumption and Production
Fingerprint
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Collaborations and top research areas from the last five years
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Artificial Intelligence-Powered Raman Spectroscopy through Open Science and FAIR Principles
Coca-Lopez, N., Alcolea-Rodriguez, V., Bañares, M. A., Brockhauser, S., Gorenflot, J., Henderson, A., Hildebrandt, R., Jeliazkova, N., Kochev, N., Diz, E. L., Pilat, Z., Polli, D., Strömert, P., Sturm, C., Vanna, R. & Portela, R., 27 Oct 2025, In: ACS Nano.Research output: Contribution to journal › Article › peer-review
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Cold-induced fibrosis and metabolic remodeling in the turtle (Trachemys scripta) ventricle
Keen, A. N., McConnell, J. C., Mackrill, J. J., Marrin, J., Holsgrove, A. J., Crossley, J., Henderson, A., Galli, G. L. J., Crossley, D. A., Sherratt, M. J., Gardner, P. & Shiels, H. A., 1 Apr 2025, In: Acta Physiologica. 241, 4, 18 p., e70026.Research output: Contribution to journal › Article › peer-review
Open Access -
The international society for clinical spectroscopy; reflections on the first 10 years
Baranska, M., Byrne, H. J., Gardner, P., Henderson, A., Stone, N. & Wood, B., 19 Jun 2025, In: The Analyst. 150, p. 3237 3246 p.Research output: Contribution to journal › Article › peer-review
Open Access -
PCA, PC-CVA, and Random Forest of GCIB-SIMS Data for the Elucidation of Bacterial Envelope Differences in Antibiotic Resistance Research
Fransson, A., Nilsson, K. D., Henderson, A., Farewell, A. & Fletcher, J. S., 3 Sept 2024, In: Analytical Chemistry.Research output: Contribution to journal › Article › peer-review
Open Access -
Weakly Supervised Anomaly Detection Coupled with Fourier Transform Infrared (FT-IR) Spectroscopy for the Identification of Non-normal Tissue
Ferguson, D., Henderson, A., Mcinnes, E. F. & Gardner, P., 11 Jul 2023, (E-pub ahead of print) In: Analyst. 148, 16Research output: Contribution to journal › Article › peer-review
Open Access
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RAI: Centre for Robotics and Artificial Intelligence
Cangelosi, A. (PI), Lennox, B. (PI), Weightman, A. (CoI), Dennis, L. (CoI), Dixon, C. (CoI), Fisher, M. (CoI), Herrmann, G. (CoI), Dickson, A. (CoI), Lanzon, A. (CoI), Stancu, A. (CoI), Miller, A. (CoI), Freitas, A. (CoI), Nini, A. (CoI), Voronkov, A. (CoI), Brass, A. (CoI), Vijayaraghavan, A. (CoI), Parslew, B. (CoI), crowther, W. (CoI), Grieve, B. (CoI), Adorno, B. (CoI), Jay, C. (CoI), Wang, C. C. L. (CoI), Todd, C. (CoI), Soutis, C. (CoI), Arsene, C. (CoI), Dresner, D. (CoI), Barrett, E. (CoI), Gowen, E. (CoI), Arvin, F. (CoI), Podd, F. (CoI), Brown, G. (CoI), Reger, G. (CoI), Cooper, G. (CoI), Mairs, H. (CoI), Yin, H. (CoI), Kinloch, I. (CoI), Eleftheriou, I. (CoI), Li, J. (CoI), Carrasco Gomez, J. (CoI), Ainsworth, J. (CoI), Sinha, J. (CoI), Ozanyan, K. (CoI), Smith, K. (CoI), Twomey, K. (CoI), Margetts, L. (CoI), Ren, L. (CoI), Zhang, L. (CoI), Cordeiro, L. (CoI), Rattray, M. (PI), Bissett, M. (CoI), Elliot, M. (CoI), Alvarez, M. (CoI), Luján, M. (CoI), Nabawy BSc, MSc, PhD, MRAeS, SMAIAA, FHEA, M. (CoI), Peek, N. (CoI), Marjanovic, O. (CoI), Dorn, O. (CoI), Dudek, P. (CoI), Green, P. (CoI), Connolly, P. (CoI), Da Silva Bartolo, P. J. (CoI), Gardner, P. (CoI), Martin, P. (CoI), Potluri, P. (CoI), Curtis, R. (CoI), Schmidt, R. (CoI), Banach, R. (CoI), Batista-Navarro, R. T. (CoI), Kaski, S. (CoI), Midson, S. (CoI), Watson, S. (CoI), Holm, S. (CoI), Furber, S. (CoI), Schlegel, V. (CoI), Mirihanage, W. (CoI), Mansell, W. (CoI), Pan, W. (CoI), Sampson, B. (CoI), Sellers, W. (CoI), Yang, W. (CoI), Cai, P. (CoI), Sun, Y. (CoI), Alharthi, A. (Researcher), Macario Rojas, A. (Researcher), Serhan, B. (Researcher), Yu, C. (Researcher), Abara, D. (Researcher), Lopez Pulgarin, E. (Researcher), Faruq, F. (Researcher), Tavella, F. (Researcher), Semeraro, F. (Researcher), Liu, G. (Researcher), Fang, G. (Researcher), Niu, H. (Researcher), Taylor, H. (PI), Zhu, H. (PGR student), Collenette, J. (Researcher), Amano, K. (Researcher), Lo, K. C. J. (PGR student), Raggioli, L. (Researcher), Romeo, M. (Researcher), Ruocco, M. (PGR student), Ghaffari Saadat, M. (Researcher), Walmsley, M. (Researcher), Mubarik, A. (Researcher), Vinanzi, S. (Researcher), Su, Y.-H. (PGR student), McAleese, H. (PGR student), Stringer, P. (PGR student), Stoican, R. (PGR student), Ye, R. (PGR student), Kurawa, S. S. (PGR student), Zhang, T. (PGR student), Krywonos, W. (PGR student), Xu, Y. (PGR student), Tian, Y. (PGR student), Henderson, A. (Technical team), Morley, D. (Support team), Tallentire, J. (Support team), Smith, J. (Support team), Hawthornthwaite, S. (Support team), Carlson, J. (Support team) & Baniqued, P. D. (Researcher)
Project: Research
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High Resolution Metabolomics – generating a step change in metabolomics at Manchester with the Orbitrap IQ-X
Hollywood, K. (PI), Barran, P. (CoI), Breitling, R. (CoI), Brockhurst, M. (CoI), Buckley, M. (CoI), Cameron, D. (CoI), Delneri, D. (CoI), Dickson, A. (CoI), Dixon, N. (CoI), Field, R. (CoI), Flitsch, S. (CoI), Green, A. (CoI), Henderson, A. (CoI), Lovelock, S. (CoI), Micklefield, J. (CoI), Nixon, S. (CoI), Pitt, A. (CoI), Scrutton, N. (CoI), Takano, E. (CoI), Trivedi, D. (CoI), Turner, N. (CoI) & Wong, L. S. (CoI)
1/08/23 → 31/07/24
Project: Research
Datasets
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Video - Alex Henderson - Open Research Conference 2024 (Subtitled)
Henderson, A. (Creator), University of Manchester Figshare, 14 Aug 2024
DOI: 10.48420/26678713, https://figshare.manchester.ac.uk/articles/presentation/Video_-_Alex_Henderson_-_Open_Research_Conference_2024_Subtitled_/26678713
Dataset
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Exploring AdaBoost and Random Forests machine learning approaches for infrared pathology on unbalanced data sets
Tang, J. (Creator), Henderson, A. (Creator) & Gardner, P. (Creator), University of Manchester, 18 May 2021
Dataset
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Quantum Cascade Laser Spectral Histopathology: Breast Cancer Diagnostics Using High Throughput Chemical Imaging
Pilling, M. (Creator), Henderson, A. (Creator) & Gardner, P. (Creator), Zenodo, 19 Jun 2017
Dataset
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Slides – Alex Henderson – Open Research Conference 2024
Henderson, A. (Creator), University of Manchester Figshare, 8 May 2024
DOI: 10.48420/25768476, https://figshare.manchester.ac.uk/articles/presentation/Slides_Alex_Henderson_Open_Research_Conference_2024/25768476
Dataset
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Infrared Chemical Image of a Breast Cancer Tissue Microarray
Tang, J. (Creator), Henderson, A. (Creator) & Gardner, P. (Creator), University of Manchester, 18 May 2021
Dataset