Amlan Chakraborty

Amlan Chakraborty


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The circadian mechanism in chronic inflammatory disease

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Personal profile


My research interest is in understanding the intricate role of immune cells in airway inflammation and remodeling associated with asthma. My research is focussed into:

Understanding the circadian mechanism of asthma- Asthma is very rhythmic.  I will examine how clocks in the brain and lung contribute to the rhythmicity observed in asthma and define processes within the disease that are under the control of these clocks. This will lead to better management and treatment of patients with asthma, by revealing new drug targets and providing the timing information needed to use existing asthma treatments at the best time of the day.

Immunomodulation and anti-remodeling in chronic allergic airway disease using nanoparticles- One of my other research interests is in developing nanoparticle-based therapeutics by conjugating anti-fibrotic and amino acid molecules for preventing airway remodeling and airway inflammation.


Dr Amlan Chakraborty has an interest in unravelling the mechanisms by which innate immune cells play a role in airway inflammation and remodelling associated with chronic allergic airway disease (asthma). He has a masters degree by research followed by a PhD with Prof Cordelia Selomulya (UNSW, Sydney) and Prof Magdalena Plebanski (Translational Immunology, RMIT University, Melbourne) in developing novel immunomodulators to target airway inflammation associated with acute lung injury and asthma.

In 2019, he continued his role as a postdoctoral research associate with Prof. Selomulya investigating the interaction of peptide-conjugated nanoparticles in airway inflammation associated with asthma. In 2020, he was recruited as a postdoctoral research fellow in the Fibrosis Group, led by Prof. Chrishan Samuel at the Department of Pharmacology,  Monash Biomedicine Discovery Institute  Following that, Amlan got 2 industry-funded fellowships to investigate the role of induced pluripotent stem cells (iPSC) in pulmonary fibrosis and understanding the role of epithelial cell-repair and associated remodeling in chronic allergic airway disease (asthma). 

Amlan has contributed to >20 publications, 7 patents (pending ratification) and has attracted $200K in commercial funding. Since completing his PhD in Pulmonary Immunology and Nanomedicine (2019, Monash University), his research focused on understanding airway remodeling and developing therapies using nanoparticles for pulmonary fibrosis and airway remodeling associated with asthma.

He has developed the anti-fibrotic hormone, serelaxin conjugated to nanoparticles for attenuation of airway inflammation and targeting airway remodeling. He also uses functionalized nanoparticles to understand the role of pulmonary myeloid cells associated with airway remodeling in asthma. Additionally, owing to the physicochemical properties of these particles, they can be traced inside the lung using a novel 3D ultra-short echo time Magnetic Resonance Imaging or using histochemical approaches.

Recently, Amlan has his research interest in understanding the circadian mechanisms in asthma.

Social responsibility

Amlan has been involved in the "Pen-Pal program" to outreach, mentor, and engage young school children in science. He recently gained media popularity for his exciting research on developing inhalable nanoparticle immunomodulators to attenuate airway inflammation in the 4th annual industry showcase organised by BDI, Monash University, Melbourne.


  • Bachelor of Technology (B.Tech) in Biotechnology
  • Master of Technology ( in Biotechnology
  • PhD- Pulmonary Immunology, Nanomedicine

My collaborations

  • Prof. Chrishan Samuel- Dy. Head (Research) & Cardiovascular Disease Program, Biomedicine Discovery Institute
  • Dr. Simon G. Royce- Respiratory Pharmacology, Monash University
  • Prof. Magdalena Plebanski- RMIT University, Melbourne
  • Prof. Cordelia Selomulya- UNSW, Sydney
  • Dr. Kamal Dua- Dept. of Pharmacy, UTS, Sydney
  • Dr. Dinesh K. Chellapan- Dept. of Pharmacy, International Medical University, Malaysia
  • Prof. Sarika Saxena- Structural Biology, Amity Institute of Biotechnology, India
  • Prof. Rajshree Das- Microbiology, Amity Institute of Biotechnology, India

Supervision information

  • Master's thesis: 4 completed, 1 in progress.
  • Honors thesis: 4 completed, 1 in progress
  • Pharmacology in action project: 3 thesis

Further information

Google Scholar Profile:

Units taught

  • MSci Journal Club- DIIRM, University of Manchester.
  • BMS5014- Research Techniques in Molecular & Cellular Biology, Biomedicine Discovery Institute, Monash University.
  • IMM3051- Principles of Applied Immunology, Dept. of Immunology, Monash University
  • IMM2011- Basic Immunology, Dept. of Immunology, Monash University
  • BMS1062- Molecular Biology, Dept. of Immunology, Monash University

Prizes and awards

  • Travel Grant EMBL- EAPS 2018.
  • Travel Grant by Monash Post-Graduate Association for ERS 2018
  • People's Choice Best Presenter Award- University of Western Australia, Perth

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Doctor of Philosophy, On the development of Immunomodulators for Attenuation of Airway Inflammation, Monash University

Award Date: 24 Jul 2019

Master of Biological Science, Kinetics of DNA unwinding by the RecD2 helicase, Amity Institute of Biotechnology, Amity University Uttar Pradesh

Award Date: 5 Nov 2015

External positions

Honorary Research Fellow, Monash University

Areas of expertise

  • QR180 Immunology
  • Asthma
  • Respiratory Medicine
  • Airway Remodelling

Research Beacons, Institutes and Platforms

  • Biotechnology


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