Andrew King

2024

Genetic findings in people with schwannomas who do not meet clinical diagnostic criteria for NF2-related schwannomatosis

Smith, M. J., Perez-Becerril, C., van der Meer, M., Burghel, G. J., Waller, S. J., Carney, M., Bunstone, S., Fryer, K., Bowers, N. L., Hartley, C. L., Smith, P. T., Rutherford, S. A., Freeman, S. R., Lloyd, S. K. W., Pathmanaban, O. N., King, A. T., Halliday, D., Duff, C. & Evans, D. G., 23 Oct 2024, In: Journal of Medical Genetics. 61, 11, p. 1011-1015 5 p.

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Hypoxia coordinates the spatial landscape of myeloid cells within glioblastoma to affect survival

Haley, M. J., Bere, L., Minshull, J., Georgaka, S., Garcia-Martin, N., Howell, G., Coope, D. J., Roncaroli, F., King, A., Wedge, D. C., Allan, S. M., Pathmanaban, O. N., Brough, D. & Couper, K. N., 17 May 2024, In: Science Advances. 10, 20, eadj3301.

Research output: Contribution to journal › Article › peer-review

Open Access

Low-dose GBCA administration for brain tumour dynamic contrast enhanced MRI: a feasibility study.

Lewis, D., Li, K.-L., Waqar, M., Coope, D., Pathmanaban, O., King, A., Djoukhadar, I., Zhao, S., Cootes, T., Jackson, A. & Zhu, X., 28 Feb 2024, In: Scientific Reports. 14, 4905 .

Research output: Contribution to journal › Article › peer-review

Open Access

Venous thromboembolism chemical prophylaxis after skull base surgery

Waqar, M., Yaseen, O., Chadwick, A., Lee, J. X., Khan, G., Evans, D. G., Horner, D., Jaiswal, A., Freeman, S., Bhalla, R., Lloyd, S., Hammerbeck-Ward, C., Rutherford, S. A., King, A. T. & Pathmanaban, O. N., 3 Apr 2024, In: Acta Neurochirurgica. 166, 1, 165.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

A Novel Multi-Model High Spatial Resolution Method for Analysis of DCE MRI Data: Insights from Vestibular Schwannoma Responses to Antiangiogenic Therapy in Type II Neurofibromatosis

Li, K.-L., Lewis, D., Zhu, X., Coope, D. J., Djoukhadar, I., King, A. T., Cootes, T. & Jackson, A., 11 Sept 2023, In: Pharmaceuticals. 16, 9, 23 p., 1282.

Research output: Contribution to journal › Article › peer-review

Open Access

Increased Circulating Chemokines and Macrophage Recruitment in Growing Vestibular Schwannomas

Hannan, C. J., Lewis, D., O'Leary, C., Waqar, M., Brough, D., Couper, K. N., Dyer, D. P., Vail, A., Heal, C., Macarthur, J., Cooper, C., Hammerbeck-Ward, C., Evans, D. G., Rutherford, S. A., Lloyd, S. K., Mackenzie Freeman, S. R., Coope, D. J., King, A. T. & Pathmanaban, O. N., 1 Mar 2023, In: Neurosurgery. 92, 3, p. 581-589 9 p.

Research output: Contribution to journal › Article › peer-review

Reported hearing outcome measures following stereotactic radiosurgery for vestibular schwannoma: A scoping review

Almufarrij, I., Hannan, C. J., King, A. T., Vail, A., Heal, C., Whitfield, G., Pathmanaban, O. N., Lloyd, S. K. & Munro, K. J., 2023, In: Journal of Neurological Surgery Part B: Skull Base.

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The clinical, genetic, and immune landscape of meningioma in patients with NF2-schwannomatosis

Gregory, G. E., Islim, A. I., Hannan, C. J., Jones, A. P., Hammerbeck-Ward, C., Rutherford, S. A., Freeman, S. R., Lloyd, S., Kalamarides, M., Smith, M. J., Couper, K., McBain, C. A., Jenkinson, M. D., Brough, D., King, A. T., Evans, D. G. & Pathmanaban, O. N., 3 Jun 2023, In: Neuro-Oncology Advances. 5, Suppl 1, p. i94-i104

Research output: Contribution to journal › Article › peer-review

Open Access

The comparable tumour microenvironment in sporadic and NF2-related schwannomatosis vestibular schwannoma

Gregory, G., Jones, A. P., Haley, M., Hoyle, C., Zeef, L., Lin, I.-H., Coope, D., King, A., Evans, D. G., Paszek, P., Couper, K., Brough, D. & Pathmanaban, O., 21 Jul 2023, In: Brain Communications. 5, 4, 64 p., fcad197.

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Open Access

2022

Beyond Antoni: A Surgeon's Guide to the Vestibular Schwannoma Microenvironment

Hannan, C. J., Lewis, D., O'Leary, C., Donofrio, C. A., Evans, D. G., Stapleton, E., Freeman, S. R., Lloyd, S. K., Rutherford, S. A., Hammerbeck-Ward, C., Brough, D., Allan, S. M., Coope, D., King, A. T. & Pathmanaban, O. N., Jan 2022, In: Journal of neurological surgery. Part B, Skull base. 83, 1, p. 1-10 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Surrogate vascular input function measurements from the superior sagittal sinus are repeatable and provide tissue-validated kinetic parameters in brain DCE-MRI

Lewis, D., Zhu, X., Coope, D., Zhao, S., King, A., Cootes, T., Jackson, A. & Li, K.-L., 24 May 2022, In: Scientific Reports. 12, 1, 14 p., 8737.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

Disease course of neurofibromatosis type 2: a 30-year follow-up study of 353 patients seen at a single institution

Forde, C., King, A. T., Rutherford, S. A., Hammerbeck-Ward, C., Lloyd, S. K., Freeman, S. R., Pathmanaban, O. N., Stapleton, E., Thomas, O. M., Laitt, R. D., Stivaros, S., Kilday, J.-P., Vassallo, G., McBain, C., Kerrigan, S., Smith, M. J., McCabe, M. G., Harkness, E. F. & Evans, D. G., 1 Jul 2021, In: Neuro-Oncology. 23, 7, p. 1113-1124 12 p.

Research output: Contribution to journal › Article › peer-review

Long-Term Outcomes of the Electrically Unresponsive, Anatomically Intact Facial Nerve Following Vestibular Schwannoma Surgery

Shoakazemi, A., Feria, A., Kanakis, C. E., Stapleton, E., Pathmanaban, O. N., Freeman, S. R., Lloyd, S., Rutherford, S. A., King, A. T. & Hammerbeck-Ward, C. L., 1 Mar 2021, In: Journal of Neurological Surgery Part B: Skull Base. 83, 4, p. 367-373

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Open Access

The importance of genetic counseling and screening for people with pathogenic SMARCE1 variants: A family study

Shoakazemi, A., Hewitt, A., Smith, M. J., Thomas, O., Stivaros, S. M., Deniz, K., Hammerbeck-Ward, C., Rutherford, S. A., King, A. T. & Evans, D. G., Jan 2021, In: American Journal of Medical Genetics. Part A.

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Translabyrinthine resection of NF2 associated vestibular schwannoma with cochlear implant insertion

Hannan, C., Sharma, P., Smith, M. E., Glancz, L., O'Driscoll, M., King, A., Hammerbeck-Ward, C., Evans, D. G., Rutherford, S., Lloyd, S. K., Freeman, S. & Pathmanaban, O., 1 Oct 2021, In: Neurosurgical Focus: Video. 5, 2

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2020

Sporadic vestibular schwannoma: a molecular testing summary

Sadler, K., Bowers, N. L., Hartley, C., Smith, P. T., Tobi, S., Wallace, A. J., King, A., Lloyd, S. K. W., Rutherford, S., Pathmanaban, O. N., Hammerbeck-Ward, C., Freeman, S., Stapleton, E., Taylor, A., Shaw, A., Halliday, D., Smith, M. J. & Evans, D. G., 23 Jun 2020, In: Journal of Medical Genetics. 58, 4, p. 227-233 7 p.

Research output: Contribution to journal › Article › peer-review

The microenvironment in sporadic and neurofibromatosis type II-related vestibular schwannoma: the same tumor or different? A comparative imaging and neuropathology study

Lewis, D., Donofrio, C. A., O'Leary, C., Li, K.-L., Zhu, X., Williams, R., Djoukhadar, I., Agushi, E., Hannan, C. J., Stapleton, E., Lloyd, S. K., Freeman, S. R., Wadeson, A., Rutherford, S. A., Hammerbeck-Ward, C., Evans, D. G., Jackson, A., Pathmanaban, O. N., Roncaroli, F. & King, A. T. & 1 others, Coope, D. J., 29 May 2020, In: Journal of neurosurgery. 134, 5, p. 1419-1429 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2019

[18F]fluorothymidine and [18F]fluorodeoxyglucose PET Imaging Demonstrates Uptake and Differentiates Growth in Neurofibromatosis 2 Related Vestibular Schwannoma

Anton-rodriguez, J. M., Lewis, D., Djoukhadar, I., Russell, D., Julyan, P., Coope, D., King, A. T., Lloyd, S. K. L., Evans, D. G., Jackson, A. & Matthews, J. C., 2019, In: Otology and Neurotology. p. 1

Research output: Contribution to journal › Article › peer-review

Open Access

Identifying the deficiencies of current diagnostic criteria for neurofibromatosis 2 using databases of 2777 individuals with molecular testing

The English Specialist NF2 research group, 1 Jul 2019, In: Genetics in Medicine. 21, 7, p. 1525-1533 9 p.

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Incidence of mosaicism in 1055 de novo NF2 cases: Much higher than previous estimates with high utility of Next Generation Sequencing.

English Specialist NF research group, 5 Jul 2019, In: Genetics in Medicine.

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Inflammation and vascular permeability correlate with growth in sporadic vestibular schwannoma

Lewis, D., Roncaroli, F., Agushi, E., Mosses, D., Williams, R., Li, K.-L., Zhu, X., Hinz, R., Atkinson, R., Wadeson, A., Hulme, S., Mayers, H., Stapleton, E., Lloyd, S. K. L., Freeman, S. R., Rutherford, S. A., Hammerbeck-Ward, C., Evans, D. G., Pathmanaban, O. & Jackson, A. & 2 others, King, A. T. & Coope, D. J., Mar 2019, In: Neuro-Oncology. 21, 3, p. 314-325 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Influence of Antiplatelet and Anticoagulant Drug Use on Outcomes after Chronic Subdural Hematoma Drainage

British Neurosurgical Trainee Research Collaborative (BNTRC) & King, A., 30 Jan 2019, (E-pub ahead of print) In: Journal of neurotrauma.

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2018

Does Drain Position and Duration Influence Outcomes in Patients Undergoing Burr-Hole Evacuation of Chronic Subdural Hematoma? Lessons from a UK Multicenter Prospective Cohort Study

British Neurosurgical Trainee Research Collaborative (BNTRC), 29 Aug 2018, In: Neurosurgery. 85, 4, p. 486-493 8 p.

Research output: Contribution to journal › Article › peer-review

Familial unilateral vestibular schwannoma is rarely caused by inherited variants in the NF2 gene

Evans, D. G., Wallace, A. J., Hartley, C., Freeman, S. R., Lloyd, S. K., Owen, T., Axon, P. R., Hammerbeck-Ward, C., Pathmanaban, O., Rutherford, S. A., Kellett, M., Laitt, R., King, A., Bischetsrieder, J., Blakeley, J. & Smith, M. J., 2018, In: The Laryngoscope. 129, 4, p. 967-973 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

High-Grade Glioma is not a Feature of Neurofibromatosis Type 2 in the Unirradiated Patient.

King, A., SA, R., C, H.-W., SK, L., SM, F., ON, P., M, R.-V., OM, T., RD, L., S, S., M, K. & DG, E., 1 Aug 2018, In: Neurosurgery.

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New Drug Candidates for Treatment of Atypical Meningiomas: an Integrated Approach Using Gene Expression Signatures for Drug Repurposing

Zador, Z., King, A. & Geifman, N., 2018, In: PLoS ONE.

Research output: Contribution to journal › Article › peer-review

Open Access

Outcomes following surgery in subgroups of comatose and very elderly patients with chronic subdural hematoma.

E, C., MTC, P., LJ, G., PJ, H., AG, K., PM, B., (BNTRC), B. N. T. R. C. & King, A., 2018, In: Neurosurgical review.

Research output: Contribution to journal › Article › peer-review

Open Access

Schwannomatosis: a genetic and epidemiological study

Evans, D. G., Bowers, N. L., Tobi, S., Hartley, C., Wallace, A. J., King, A. T., Lloyd, S. K. W., Rutherford, S. A., Hammerbeck-Ward, C., Pathmanaban, O. N., Freeman, S. R., Ealing, J., Kellett, M., Laitt, R., Thomas, O., Halliday, D., Ferner, R., Taylor, A., Duff, C. & Harkness, E. F. & 1 others, Smith, M. J., Nov 2018, In: Journal of Neurology, Neurosurgery and Psychiatry. 89, 11, p. 1215-1219 5 p.

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Spinal ependymomas in NF2: a surgical disease?

Kalamarides, M., Essayed, W., J.P., L., Aboukais, R., Sterkers, O., Bernardeschi, D., Peyre, M., Lloyd, S., Freeman, S., Hammerbeck-Ward, C. L., Kellett, M., Rutherford, S. A., Evans, D. G., Pathmanaban, O. & King, A., 1 Feb 2018, In: Journal of Neuro-Oncology. 136, 3, p. 605-611 6 p.

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2017

Association of Genetic Predisposition With Solitary Schwannoma or Meningioma in Children and Young Adults

Pathmanaban, O., Sadler, K. V., Kamaly-Asl, I., King, A., Rutherford, S. A., Hammerbeck-Ward, C., Mccabe, M., Kilday, J.-P., Beetz, C., Poplawski, N. K., Evans, D. & Smith, M. J., 1 Sept 2017, In: JAMA Neurology. 74, 9, p. 1123-1129 7 p.

Research output: Contribution to journal › Article › peer-review

Long-term Quality of Life Following Vestibular Schwannoma Excision Via the Translabyrinthine Approach

Broomfield, S. J., Mandavia, A. K., Nicholson, J. S., Mahmoud, O., King, A. T., Rutherford, S. A. & Ramsden, R. T., Sept 2017, In: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 38, 8, p. 1165-1173 9 p.

Research output: Contribution to journal › Article › peer-review

Revisiting Neurofibromatosis type 2 diagnostic criteria to exclude LZTR1 related schwannomatosis

Smith, M., Bowers, N. L., Bulman, M., Gokhale, C., Wallace, A. J., King, A., Lloyd, S., Rutherford, S. A., Hammerbeck-Ward, C. L., Freeman, S. R. & Evans, G., 3 Jan 2017, In: Neurology. 88, 1, p. 87 92 p.

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2016

Auditory Brainstem Implantation in Neurofibromatosis Type 2: Experience From the Manchester Programme

Ramsden, R. T., Freeman, S. R. M., Lloyd, S. K. W., King, A., Shi, X., Ward, C. L., Huson, S. M., Mawman, D. J., O'Driscoll, M. P., Evans, D. G., Rutherford, S. A. & Manchester Neurofibromatosis Type 2 Service, 12 Aug 2016, In: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.

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Open Access

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Intraoperative Supratentorial Extradural Hematoma Complicating Excision of a Giant Vestibular Schwannoma

Lewis, D. G., Lloyd, S., Pathmanaban, O., Hammerbeck-Ward, C., Rutherford, S. A. & King, A. T., May 2016, In: World Neurosurgery. 89, p. 726.e15–726.e17

Research output: Contribution to journal › Article › peer-review

Outcomes of cochlear implantation in patients with neurofibromatosis type 2

North, H. J. D., Mawman, D., O'Driscoll, M., Freeman, S. R., Rutherford, S. A., King, A. T., Hammerbeck-Ward, C., Evans, D. G. & Lloyd, S. K. W., 2016, In: Cochlear Implants International. 17, 4, p. 172-177 6 p.

Research output: Contribution to journal › Article › peer-review

Predictors of Outcome in Traumatic Brain Injury: New Insight Using Receiver Operating Curve Indices and Bayesian Network Analysis

Zador, Z., Sperrin, M. & King, A., 7 Jul 2016, In: PLoS ONE. 11, 7, p. e0158762

Research output: Contribution to journal › Article › peer-review

Open Access

2015

Clinical and molecular predictors of mortality in neurofibromatosis 2: a UK national analysis of 1192 patients.

Hexter, A., Jones, A., Joe, H., Heap, L., Smith, M., Wallace, A., Halliday, D., Parry, A., Taylor, A., Raymond, L., Shaw, A., Afridi, S., Obholzer, R., Axon, P., King, A., Friedman, J., Evans, D. & Evans, G., Oct 2015, In: Journal of Medical Genetics. 52, 10, p. 699-705 6 p.

Research output: Contribution to journal › Article › peer-review

Clinical and radiological guidance in managing facial nerve schwannomas.

J, D., R, H., SR, F., GM, P., CL, W., SA, R., King, A., RT, R. & SK, L., 2015, In: Otology and Neurotology. 36, 5, p. 892-895 4 p.

Research output: Contribution to journal › Article › peer-review

Multiple synchronous sites of origin of vestibular schwannomas in neurofibromatosis Type 2.

Stivaros, S. M., Stemmer-Rachamimov, A. O., Alston, R., Plotkin, S. R., Nadol, J. B., Quesnel, A., O'Malley, J., Whitfield, G. A., McCabe, M. G., Freeman, S. R., Lloyd, S. K., Wright, N. B., Kilday, J.-P., Kamaly-Asl, I. D., Mills, S. J., Rutherford, S. A., King, A. & Evans, D. G., Aug 2015, In: Journal of Medical Genetics. 52, 8

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Progress of hearing loss in neurofibromatosis type 2: implications for future management

Kontorinis, G., Nichani, J., Freeman, S. R., Rutherford, S. A., Mills, S., King, A. T., Mawman, D., Huson, S., O'Driscoll, M., Gareth Evans, D. & Lloyd, S. K. W., Nov 2015, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 272, 11, p. 3143-50 8 p.

Research output: Contribution to journal › Article › peer-review

Subjective outcomes of auditory brainstem implantation.

McSorley, A., Freeman, S., Ramsden , R., Motion, J., King, A., Rutherford, S., Mawman, D., O’Driscoll, M. & Lloyd , S., 2015, In: Otology and Neurotology. 36, 5

Research output: Contribution to journal › Article › peer-review

2014

Geniculate neuralgia: a systematic review.

Tang, I. P., Freeman, S. R., Kontorinis , G., Tang, M. Y., Rutherford, S. A., King, A. & Lloyd , S. K. W., 2014, In: Journal of Laryngology and Otology. 128, 5, p. 394-399

Research output: Contribution to journal › Article › peer-review

Ipsilateral cochlear implantation after cochlear nerve preserving vestibular schwannoma surgery in patients with neurofibromatosis type 2

Lloyd, S. K. W., Glynn, F. J., Rutherford, S. A., King, A., Mawman, D. J., O'Driscoll, M. P., Evans, D. G. R., Ramsden, R. T. & Freeman, S. R. M., Jan 2014, In: Otology and Neurotology. 35, 1, p. 43-51 8 p.

Research output: Contribution to journal › Article › peer-review

2013

Pilot study of perioperative accidental durotomy: does the period of postoperative bed rest reduce the incidence of complication?

JC, L., B, V. N., SA, R. & King, A., 2013, In: British journal of neurosurgery. 27, 6, p. 800-802 3 p.

Research output: Contribution to journal › Article › peer-review

Andrew King, FRCS

Research output

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