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Personal profile

Overview

I am Professor of Respiratory Medicine and Deputy Head of the Division of Infection, Immunity and Respiratory Medicine in the School of Biological Sciences. I am an Honorary Consultant Respiratory Physician at Wythensahwe Hospital (Manchester University NHS Foundation Trust) and conduct asthma and allergy clinics as well as general respiratory medicine clinics. My research focusses on early life risk factors for asthma and allergies, in particular phenotypes, endotypes and genetic epidemiology. I coordinate the MRC funded national network of five asthma birth cohort studies (Study Team for Early Life Asthma Research) and am co-investigator of the Manchester Asthma and Allergy Study. I am the asthma and allergy lead within the respiratory theme of the Manchester Biomedical Research Centre. I am an investigator on the EU funded Integrated Approaches to Food Allergen and Allergy Risk Management (iFAAM). I am chief investigator of the Manchester Allergy Respiratory and Thoracic Surgery Biobank at Wythensahwe Hospital. I am clinical lead for the Food Standards Agency funded Prevalenc of Adult Food Allergy Study.

Biography

Having completed clinical training in Respiratory and General Internal Medicine in the North West Regional Rotation, I was appointed Senior Lecturer in Asthma and Allergy Research at the University of Manchester and Honorary Consultant Respiratory Physician at Wythenshawe Hospital in January 2005. I was promoted to Professor of Respiratory Medicine in 2011. I have published extensively in the field of early life risk factors for asthma and allergy including genetic and epidemiological studies. Working with collaborators at Microsoft research, we pioneered the use of machine learning techniques in the field, to improve our understanding of phenotypes in allergic disease. I continue to collaborate with investigators at Imperial College London on the flagship award from BBSRC/MRC systems immunology of the human life course award.

Research interests

  • Early life risk factors for asthma and allergies
  • Gene environment interactions in respiratory disease
  • Asthma diagnostics
  • Food allergy

Key Words

  • Asthma
  • Allergy
  • Genetics
  • Birth cohorts
  • Food allergy

Methodological knowledge

  • Birth cohort studies
  • Assessment of environmental exposures
  • Genotyping

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 2 - Zero Hunger
  • SDG 3 - Good Health and Well-being
  • SDG 11 - Sustainable Cities and Communities
  • SDG 15 - Life on Land

Education/Academic qualification

FRCP, Royal College of Physicians

Award Date: 1 May 2013

Doctor of Philosophy, Genetic and Environmental Factors in Asthma and Allergic Diseases , The University of Manchester

Award Date: 1 May 2009

Doctor of Medicine, The University of Manchester

Award Date: 1 Jun 2000

Bachelor of Medicine and Bachelor of Surgery, The University of Manchester

Award Date: 5 Jul 1991

Bachelor of Arts, Physiological Sciences (medicine), Oxford University

Award Date: 1 Jun 1988

Areas of expertise

  • R Medicine (General)
  • asthma
  • allergy
  • food allergy
  • Diagnostics
  • genetics

Research Beacons, Institutes and Platforms

  • Digital Futures
  • Lydia Becker Institute

Keywords

  • asthma
  • allergy
  • genetics
  • Epidemiology
  • phenotypes

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