Research output per year
Research output per year
Personal profile
Overview
A focus of my laboratory over the years has been the mechanisms that control cell plasticity, cell migration and invasion, definitive characteristics of malignant cells essential for metastasis. Recently, we have been studying these phenomena in the context of KRAS-mutant lung adenocarcinoma and small-cell lung cancer. We have also been addressing KRAS-mutant isoform-selective signalling and functions in lung cancer development, progression and response to therapies in close collaboration with Dr Colin Lindsay at Christie Hospital, Manchester.
Opportunities
PhD opportunities
Projects are now available within our team for motivated PhD candidates to work on SCLC plasticity, invasion and metastasis:
Follow the links for more information about the projects and how to apply.
Education/Academic qualification
Doctor of Philosophy, National Hellenic Research Foundation
1990 → 1994
Bachelor of Science, Panepistimio Patron - University of Patras
1985 → 1989
External positions
Member of the MRC College of Experts, Medical Research Council (MRC)
2026 → …
Member of the Scientific Advisory Committee , Yorkshire Cancer Research Sheffield Pioneers Fund
2022 → 2025
Review panel member , Research Council of Biosciences, Health and Environment, Academy of Finland
2021 → 2023
Member of the Molecular and Cellular Medicine Board, Medical Research Council (MRC)
Jun 2017 → May 2021
Scientific Advisory Committee, Worldwide Cancer Research
Mar 2013 → Dec 2017
Editorial Board, Small GTPases - Taylor & Francis Online
Editorial Board, FEBS Letters
Research Beacons, Institutes and Platforms
- Manchester Cancer Research Centre
Accepting PhD students
- Accepting PhD students
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
-
SDG 3 Good Health and Well-being -
SDG 7 Affordable and Clean Energy
Fingerprint
Dive into the research topics where Angeliki Malliri is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Correction: A stretchable and biomimetic polyurethane membrane for lung alveolar in vitro modelling
Mitta, E., Gilmore, A., Malliri, A. & Cartmell, S. H., 16 Feb 2026, In: Scientific Reports. 16, 1, 6375.Research output: Contribution to journal › Commentary/debate › peer-review
Open Access -
Distinct sub-clusters of developmental disorder-associated variants in the switch II region of RAC1
Althebaiti, H. O., Cooksedge, J., Baker, M. J., Smith, M., Edwards-Scott, V., Pessoa, A. L. S., Margot, H., Metcalfe, K. A., Fradin, M., Mostow, H., Alders, M., Lakeman, P., Malliri, A., Banka, S. & Millard, T. H., 12 May 2026, (E-pub ahead of print) In: European journal of human genetics : EJHG.Research output: Contribution to journal › Article › peer-review
-
Targeting KRAS codon 13 mutations using direct combination approaches in non-small cell lung cancer
Mcdaid, W., Adderley, H., D'Arienzo, P., Sofia Da Silva Oliveira, A., Woodhouse, L., Tinsley, K., Cooksedge, J., Baker, M., Searle, J., Walwyn-Brown, K., Carter, M., Wedge, D., Malliri, A., Lindsay, C. & al, E., 17 Jun 2026, (Accepted/In press) In: Cancer discovery.Research output: Contribution to journal › Article › peer-review
-
The E3 ubiquitin ligase HUWE1 is required for KRAS-induced lung cancer
Searle, J., Menotti, M., McDaid, W. J., Baker, M. J., Chaturvedi, A., Ginn, L., Reed, H., Carter, M., Blackhall, F., Lindsay, C. R. & Malliri, A., 19 May 2026, In: Cell Death and Disease. 17, 1, 487.Research output: Contribution to journal › Article › peer-review
Open Access -
A stretchable and biomimetic polyurethane membrane for lung alveolar in vitro modelling
Mitta, E., Gilmore, A., Malliri, A. & Cartmell, S. H., Dec 2025, In: Scientific Reports. 15, 1, 14585.Research output: Contribution to journal › Article › peer-review
Open Access
Projects
- 1 Active
-
Investigating the role of RAC1 signalling in small cell lung cancer plasticity
Malliri, A. (PI), Baker, M. (CoI), Dive, C. (CoI) & Simpson, K. (CoI)
1/04/25 → 31/03/28
Project: Research
Prizes
-
Philip Godfrey Fund Memorial Award 2018 from the Biochemical Society
Malliri, A. (Recipient), Jul 2018
Prize: Prize (including medals and awards)
Activities
- 1 Membership of board
-
Medical Research Council (MRC) (External organisation)
Malliri, A. (Academic expert member)
Jun 2017 → May 2019Activity: Membership › Membership of board › Research
Press/Media
-
Scientists uncover promising new way to treat an ‘undruggable’ type of lung cancer
7/07/26
1 Media contribution
Press/Media: Research