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Professor Anthony Green

Anthony Green

Prof

 https://orcid.org/0000-0003-0454-1798

Personal profile

Overview

My team and I design and engineer enzymes – nature’s catalysts – to perform chemical reactions that don’t occur naturally. These engineered biocatalysts open the door to greener, more efficient and more selective manufacturing methods in industries like pharmaceuticals, agrochemicals, plastics recycling and biofuels.

We custom design enzymes using computational models and directed evolution which allows us to transform molecules in novel ways. Our work has led to:

  • Reengineering natural enzymes to help manufacture molnupiravir and lenacapavir, antivirals used for the treatment and prevention of COVID-19 and HIV.
  • Helping create enzymes that break down abundant plastics such as PET more effectively – the type of plastic found in disposable bottles.
  • Inventing photoenzymes powered by visible light that offer cheaper, cleaner routes to producing complex molecules.

By blending organic chemistry, computational design, and evolution in the lab, we’re helping to reduce the costs of medicines, protect the environment, and enable industries to operate more sustainably.

Research Beacons, Institutes and Platforms

  • Biotechnology
  • Sustainable Futures
  • Manchester Institute of Biotechnology
  • Manchester Environmental Research Institute

Keywords

  • Catalysis
  • biocatalysis
  • industrial biocatalysis
  • enzymes
  • enzyme design
  • directed evolution
  • genetic code expansion

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being
  2. SDG 5 - Gender Equality
    SDG 5 Gender Equality
  3. SDG 7 - Affordable and Clean Energy
    SDG 7 Affordable and Clean Energy
  4. SDG 9 - Industry, Innovation, and Infrastructure
    SDG 9 Industry, Innovation, and Infrastructure
  5. SDG 12 - Responsible Consumption and Production
    SDG 12 Responsible Consumption and Production
  6. SDG 13 - Climate Action
    SDG 13 Climate Action
  7. SDG 15 - Life on Land
    SDG 15 Life on Land

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Collaborations and top research areas from the last five years

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View all 50 research outputs
View all 24 projects
View all 7 prizes
  • 2 Membership of professional association
  • 2 Internal positions
  • 1 Membership of committee
  • 1 Career professional development
View all 6 activities