Argyris has obtained degrees from the National Technical University of Athens, Greece and Imperial College London. He carried out post-doctoral research in Cambridge and Oxford in the laboratory of Prof. Dame Carol Robinson, where he studied the structure and function of protein complexes using mass spectrometry. Since 2014 he has been running his independent research group at King’s College London focusing on developing mass spectrometry-based strategies to interrogate the structural dynamics of membrane proteins and their complexes. His group has pioneered the study of molecular mechanisms underpinning membrane protein function using the emerging hydrogen deuterium exchange-mass spectrometry (HDX-MS) technology. In particular, he established the study of lipid-mediated conformational dynamics in membrane transporters. Recently, he moved to the University of Manchester and his current interests lie in exploring how the lipid environment and pharmacologically important ligands shape the conformational landscape of challenging membrane proteins, important for human health and disease.