Bruno M Simões

Bruno M Simões, PhD, FHEA, PGCertHE


  • Breast Biology Group
    Division of Cancer Sciences
    The University of Manchester

    Manchester Cancer Research Centre
    555 Wilmslow Road
    Manchester M20 4GJ
    United Kingdom

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Personal profile


2021- Postgraduate Certificate in Higher Education (PGCertHE)

2018 - Fellow of The Higher Education Academy (FHEA)

2010 - PhD in Cell and Molecular Biology
Thesis title: “Characterisation of human breast stem/progenitor cells”
Basque Country University, CICbioGUNE, Bilbao, Spain

2004 - Graduation (equivalent to BSc + MSc) in Microbial Biology and Genetics
Faculty of Science, University of Lisbon, Portugal


I obtained my degree in Microbial Biology and Genetics at the University of Lisbon, in 2004, after completing a Research Training in Pavia (Italy).

My PhD studies were carried out in Bilbao (Spain) under the supervision of Dr Maria Vivanco and were mainly focused on analysing the effects of estrogen in human breast stem cells.

In 2011, I joined the Breast Biology group led by Professor Rob Clarke, at the University of Manchester, and since then I have been investigating the role that breast cancer stem cells play in the acquisition of endocrine therapy resistance in estrogen receptor-positive tumours.

I have also been working with Dr Sacha Howell in developing better chemoprevention approaches for women at risk of breast cancer since 2016.

Memberships of committees and professional bodies

British Association for Cancer Research (BACR)

European Association for Cancer Research (EACR)

American Association for Cancer Research (AACR)


  • Lecturer on MSc Cancer Biology and Radiotherapy Physics course

  • Lecturer on MSc Transformative Oncology

  • Academic Advisor for Medical Students (Y1 and Y2)

  • Tutor on MRes Oncology (Tutorial Unit)

  • Supervisor for Master and PhD students


  • Lecturer on MSc Cell and Tissue Culture course, Autonomous University of Guerrero, Mexico

Media contributions and coverage

Activities and esteem

  • Associate Editor for Breast Cancer - Frontiers in Oncology (2021-present)

  • Guest Associate Editor for Cancer Endocrinology - Frontiers in Endocrinology (2020-present)

  • Member of the Academic Board of PhD programme in "Translational Medicine", University of Calabria, Italy (2020-present)

  • Referee of project grant applications for Prevent Breast Cancer charity, UK, and Auckland Medical Research Foundation, New Zealand (2018-present)

  • Examiner of 4 PhD theses (2016-present)

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research Beacons, Institutes and Platforms

  • Manchester Cancer Research Centre


  • Breast Biology, Breast Cancer Stem Cells, Endocrine Resistance, Breast Cancer Prevention


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Collaborations and top research areas from the last five years

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