Research output per year
Research output per year
Catharine West is a Professor of Radiation Biology at the University of Manchester. She studied biology at York University and radiobiology at the Institute of Cancer Research, Sutton. After postdoctoral work at the University of Rochester Cancer Centre in upstate New York, she moved to Manchester in 1986. In 2002, she joined the Institute (now Division) of Cancer Sciences at the University of Manchester and established the Translational Radiobiology Group. Her research focuses on trying to predict how cancer patients respond to radiotherapy with a particular interest in measuring radiosensitivity and hypoxia. She was instrumental in setting up an international Radiogenomics Consortium, which is identifying the genetic determinants of radiotherapy toxicity. She is a chief investigator (RAPPER, REQUITE) or translational lead (TORPEdO, NIMRAD, VORTEX, CIRCCa) for national/international studies. Current/recent committee work includes CTRad, COMARE, the LH Gray Memorial Trust, NCRI Sarcoma CSG, NCRI Head & Neck CSG, Prostate Cancer UK Grant Advisory Group, EURAMED and the editorial boards of Radiation Research, Physics in Medicine & Biology and Clinical Oncology. She has published over 200 papers, and is an honorary member of the Royal College of Radiologists and an honorary fellow of the British Institute of Radiology. She was awarded the Weiss medal by the Association for Radiation Research in 2016 and the Bacq and Alexander award by the European Radiation Research Society in 2017. In 2018 she was made an Honorary Fellow of the Royal College of Radiologists.
The challenge for radiotherapy-related research is to find ways of giving as much radiation as possible to kill cancer cells while minimising the doses received by surrounding healthy tissue. The expansion of our knowledge through the Human Genome Project has been accompanied by the development of new high-throughput techniques, which provide extensive capabilities for the analysis of a large number of genes or the whole genome. There is a belief that this genomic revolution, i.e. sequencing of the human genome and developments in high throughput technology, heralds a future of personalised medicine. For radiotherapy, this progress should increase the possibility of predicting individual patient response to radiotherapy. The Translational Radiobiology Group, therefore, is interested in the characterisation of molecular profiles that reflect relevant biological phenotypes and predict tumour and normal tissue response to radiation.
Involved in or past member of several national committees including:
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Doctor of Philosophy, The effect of cytotoxic drugs and radiation on mammalian cells and multicellular spheroid in vitro, The Institute of Cancer Research (University of London)
1 Oct 1979 → 31 Mar 1983
Award Date: 10 Apr 1983
Bachelor of Arts, University of York
1 Oct 1975 → 30 Jun 1978
Award Date: 1 Sept 1978
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Choudhury, A. (PI), Kirkby, N. (CoI), Mcwilliam, A. (CoI), Van Herk, M. (CoI) & West, C. (CoI)
1/03/17 → 28/06/20
Project: Research
West, C. (Recipient), 2018
Prize: National/international honour
West, C. (Recipient), 20 Apr 2023
Prize: Prize (including medals and awards)
Stratford, I. (Participant), Williams, K. (Participant), West, C. (Participant), (Participant), (Participant), Eustace, A. (Participant) & (Participant)
Impact: Health impacts
West, C. (Corresponding participant), Choudhury, A. (Participant), Hoskin, P. (Participant) & (Participant)
Impact: Health and wellbeing, Economic
Astley, S. (Contributor), Byers, R. (Contributor), Dave, M. (Contributor), Fergie, M. (Contributor), Harkness, E. (Contributor), Linton, K. (Contributor), Rosenberg, A. (Contributor), Sperrin, M. (Contributor), Tsakiroglou, A. M. (Creator) & West, C. (Contributor), Mendeley Data, 4 Jan 2021
DOI: 10.17632/274xbhc5rx.3, https://data.mendeley.com/datasets/274xbhc5rx
Dataset
Hague, C. (Creator), Beasley, W. (Creator), Garcez, K. (Creator), Lee, L. W. (Creator), Mcpartlin, A. (Creator), Mcwilliam, A. (Creator), Ryder, D. (Creator), Sykes, A. J. (Creator), Thomson, D. (Creator), Van Herk, M. (Creator), West, C. (Creator) & Slevin, N. (Creator), figshare , 9 Apr 2018
DOI: 10.6084/m9.figshare.6116009
Dataset