Research output per year
Research output per year
Cathy has a long standing interest into the causes and prevention of vascular occlusion and stem cell approaches for treatment of myocardial infarction. She has conducted research funded by MRC, British Heart Foundation and Industry. She has served on the British Atherosclerosis Society committee, previously was an elected council member of the British Society for Cardiovascular Research and is a member of several other professional organisations. She regularly reviews manuscripts and grants for various international journals and funding agencies, she is on the Editorial Board of the journal "Clinical Science" and is Section Head for the Cardiovascular Physiology/Circulation Section in Faculty of 1000 (www.f1000.com). In addition she has held teaching roles to undergraduate medical and life science students as well as post graduate supervision. Cathy's teaching was recently recognised with the award of a Senior Fellowship from the Higher Education Academy.
Currently Honorary Senior Lecturer within the Division of Cardiovascular Sciences, University of Manchester. Prior to this position, she was Lecturer in Cardiac Sciences at the University of Sheffield (1992-2001). Her British Heart Foundation funded post-doctoral training was undertaken in the laboratory of Gianni Angelini, University of Sheffield (1990-1992) and prior to this she was awarded her PhD (1989) from The University of Sheffield on the involvement of the vasculature in the pathogenesis of autoimmune diseases.
She has previously served on the British Atherosclerosis Society Committee and the British Society for Cardiovascular Research Council and is a member of several other professional associations. She is on the Editorial Board of the jornal "Clinical Science" has co-organised several national and international meetings and regularly reviews manuscripts for international journals and grants for various funding organisations. She regularly acts as external examiner and has been invited to speak at various national and international meetings. She was awarded a Senior Fellowship from the Higher Education Academy in 2015.
Atherosclerosis leads to coronary heart disease which is responsible for more than 110,000 deaths in the UK per year; more than 1.4 million people in the suffer from angina and around 300,000 people have a heart attack each year. Thus, there remains a major requirement for investigations regarding the underlying causes and mechanisms. Vascular occlusion is a characteristic feature of several important vascular pathologies including atherosclerosis. It also occurs following the major interventional treatments for atherosclerosis ie percutaneous coronary interventions (angioplasty and stenting), and bypass graft surgery. My research focuses on the pathogenesis of atherosclerosis and vascular occlusion that occurs following stenting and bypass surgery. The role of transcription factors, in particular c-myb is being investigated as well as the role of calcium in atherogenesis. This research is performed using isolated vascular cells, whole vessels and in vivo models of atherosclerosis, restenosis and angioplasty. In addition, in collaboration with a clinical cardiologist and Industry, the use of genetically modified stem cells for the treatment of myocardial infarction is being investigated in a large animal model.
Leadership
Senior Fellow, Higher Education Academy
Senior Post Graduate Tutor, Division of Cardiovascular Sciences
Undergraduate
Lecturer: Life Sciences: BIOL30362, Cardiovascular Systems in Health and Disease
Lecturer: MBChB
Tutor, Ist year PEPs: MBChB
Tutor, 2nd Year PEPs: MBChB
Tutor, APEPs: MBChB
Project Supervisor: Intercalated BSc pathology students
Postgraduate
Previously sucessfully supervised 10 PhD students, 2 MD students and 1 MPhil student and several MRes students
Currently supervise Fatemeh Jafarzadeh's PhD (BHF 4 year PhD Programme)
Tutor and Project supervisor: MRes in Life Sciences
Module co-ordinator, tutor and project supervisor: MRes Cardiovascular Sciences
Postgraduate opportunities
Enquiries from prospective postgraduate students wishing to undertake a higher degree in the area of cardiovascular biology are welcome
Professor Yvonne Alexander
Manchester Metroploitan University
Professor Clare Austin
Edge Hill University
Professor David Eisner
University of Manchester
Professor Moustapha Kassem
University of Southern Denmark
Dr Ashraf Kitmitto
University of Manchester
Professor Andrew Lewis
Biocompatibles PLC
Dr Nadim Malik
University of Manchester
Dr Tao Wang
University of Manchester
Editorial Board, Clinical Science
British Cardiovascular Society
British Society for Cardiovascular Research - committee member
British Atherosclerosis Society-committee member
British Microcirculation Society
European Atherosclerosis Society
European Society for Microcirculation
European Vascular Biology Organisation
International Society for Heart Research
Association for European Cardiovascular Pathology
Basic Laboratory Sciences including:
Experimental models of vascular disease including atherosclerosis, restenosis and myocardial infarction
Isolation and culture of vascular cells
Determination of proliferation, apoptosis, protein & gene expression
Histopathological techniques
BSc, Hons University of Sheffield
PhD, University of Sheffield
Diploma in Management Studies
Senior Fellowship, Higher Education Academy
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Cartwright, E. (PI), Abraham, S. (CoI), Allan, S. (CoI), Ballestrem, C. (CoI), Boyett, M. (CoI), Canfield, A. (CoI), Dibb, K. (CoI), Dobrzynski, H. (CoI), Eisner, D. (CoI), Galli, G. (CoI), Heagerty, A. (CoI), Hentges, K. (CoI), Herbert, S. (CoI), Holt, C. (CoI), Humphries, M. (CoI), Keavney, B. (CoI), Kitmitto, A. (CoI), Liu, W. (CoI), Miller, C. (CoI), Oceandy, D. (CoI), Parry-Jones, A. (CoI), Saiani, A. (CoI), Sherratt, M. (CoI), Shiels, H. (CoI), Talavera, D. (CoI), Tomaszewski, M. (CoI), Trafford, A. (CoI), Venetucci, L. (CoI), Wang, X. (CoI) & Zhang, Y. (CoI)
1/10/17 → 30/09/21
Project: Research
Cartwright, E. (PI), Canfield, A. (CoI), Eisner, D. (CoI), Heagerty, A. (CoI), Holt, C. (CoI), Keavney, B. (CoI) & Kitmitto, A. (CoI)
1/10/16 → 30/09/20
Project: Research
Canfield, A. (PI), Ashton, N. (CoI), Brennan, K. (CoI), Brognard, J. (CoI) & Holt, C. (CoI)
1/05/16 → 30/04/18
Project: Research
Cartwright, E. (PI), Canfield, A. (CoI), Eisner, D. (CoI), Heagerty, A. (CoI), Holt, C. (CoI), Keavney, B. (CoI) & Kitmitto, A. (CoI)
1/10/15 → 30/09/19
Project: Research
Cartwright, E. (PI), Canfield, A. (CoI), Eisner, D. (CoI), Heagerty, A. (CoI), Holt, C. (CoI), Keavney, B. (CoI) & Kitmitto, A. (CoI)
1/10/14 → 30/09/18
Project: Research