Charles Pearman

2024

Restoring Atrial T-Tubules Augments Systolic Ca Upon Recovery From Heart Failure

Caldwell, J. L., Clarke, J. D., Smith, C. E. R., Pinali, C., Quinn, C. J., Pearman, C. M., Adomaviciene, A., Radcliffe, E. J., Watkins, A. E., Horn, M. A., Bode, E. F., Madders, G. W. P., Eisner, M., Eisner, D. A., Trafford, A. W. & Dibb, K. M., 14 Aug 2024, (E-pub ahead of print) In: Circulation research.

Research output: Contribution to journal › Article › peer-review

2023

Incremental value of the signal-averaged ECG for diagnosing arrhythmogenic cardiomyopathy

Pearman, C. M., Lee, D., Davies, B., Khan, H., Tadros, R., Cadrin-Tourigny, J., Roberts, J. D., Sanatani, S., Simpson, C., Angaran, P., Hansom, S., Ilhan, E., Seifer, C., Green, M., Gardner, M., Talajic, M., Laksman, Z., Healey, J. S. & Krahn, A., 1 Feb 2023, In: Heart Rhythm. 20, 2, p. 224-230 7 p.

Research output: Contribution to journal › Article › peer-review

2022

Sex Differences and Utility of Treadmill Testing in Long‐QT Syndrome

Yee, L. A., Han, H., Davies, B., Pearman, C. M., Laksman, Z. W. M., Roberts, J. D., Steinberg, C., Tadros, R., Cadrin‐Tourigny, J., Simpson, C. S., Gardner, M., MacIntyre, C., Arbour, L., Leather, R., Fournier, A., Green, M. S., Kimber, S., Angaran, P., Sanatani, S. & Joza, J. & 5 others, Khan, H., Healey, J. S., Atallah, J., Seifer, C. & Krahn, A. D., 20 Sept 2022, In: Journal of the American Heart Association. 11, 18, e025108.

Research output: Contribution to journal › Article › peer-review

Open Access

Shockingly shiny shoes—Inappropriate discharge from a subcutaneous defibrillator

Pearman, C. M., Popal, S., Hawkins, N. M. & Andrade, J. G., Nov 2022, In: HeartRhythm Case Reports.

Research output: Contribution to journal › Article › peer-review

2021

Complication rates following ventricular tachycardia ablation in ischaemic and non-ischaemic cardiomyopathies: a systematic review

Ding, W. Y., Pearman, C. M., Bonnett, L., Adlan, A., Chin, S. H., Denham, N., Modi, S., Todd, D. M., Hall, M. C. S. & Mahida, S., 29 Jan 2021, In: Journal of interventional cardiac electrophysiology.

Research output: Contribution to journal › Article › peer-review

Open Access

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Epidemiology of cardiac implantable electronic device infections: incidence and risk factors

Han, H.-C., Hawkins, N. M., Pearman, C. M., Birnie, D. H. & Krahn, A. D., 23 Jun 2021, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 23, 23, p. 3-10

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Open Access

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Optimising Large Animal Models of Sustained Atrial Fibrillation: Relevance of the Critical Mass Hypothesis

Denham, N., Pearman, C., Madders, G., Smith, C. E. R., Trafford, A. & Dibb, K., 15 Jun 2021, In: Frontiers in Physiology. 690897.

Research output: Contribution to journal › Article › peer-review

Open Access

PDE5 inhibition suppresses ventricular arrhythmias by reducing SR Ca2+ content

Hutchings, D., Pearman, C., Madders, G., Woods, L., Eisner, D., Dibb, K. & Trafford, A., 12 Jul 2021, (E-pub ahead of print) In: Circulation research.

Research output: Contribution to journal › Article › peer-review

Open Access

The Clinical Utility of Procainamide-induced Late Potentials on the Signal Averaged ECG

Pearman, C., Walia, J., Alqarawi, W., Larsen, J. M., Leach, E., Krahn, A. D. & Laksman, Z., 1 Dec 2021, In: PACE - Pacing and Clinical Electrophysiology. 44, 12, p. 2046-2053 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2020

Altered Atrial Cytosolic Calcium Handling Contributes to the Development of Postoperative Atrial Fibrillation

Fakuade, F. E., Steckmeister, V., Seibertz, F., Gronwald, J., Kestel, S., Menzel, J., Pronto, J. R. D., Taha, K., Haghighi, F., Kensah, G., Pearman, C. M., Wiedmann, F., Teske, A. J., Schmidt, C., Dibb, K. M., El-Essawi, A., Danner, B. C., Baraki, H., Schwappach, B. & Kutschka, I. & 2 others, Mason, F. E. & Voigt, N., 10 Jun 2020, (E-pub ahead of print) In: Cardiovascular research.

Research output: Contribution to journal › Article › peer-review

Open Access

Chronic vagal nerve stimulation has no effect on tachycardia-induced heart failure progression or excitation-contraction coupling

Radcliffe, E., Pearman, C., Watkins, A., Lawless, M., Kirkwood, G., Saxton, S., Eisner, D. & Trafford, A. (Corresponding), 20 Jan 2020, In: Physiological Reports. 8, 2, e14321.

Research output: Contribution to journal › Article › peer-review

Open Access

Relationship Between Sodium Channel Function and Clinical Phenotype in SCN5A Variants Associated with Brugada syndrome

Pearman, C., Denham, N., Mills, R. W., Ding, W. Y., Hall, M. C. S., Todd, D. M. & Mahida, S., 1 Nov 2020, (E-pub ahead of print) In: Human Mutation.

Research output: Contribution to journal › Article › peer-review

Open Access

2019

Early experience of thoracoscopic vs. catheter ablation for atrial fibrillation

Pearman, C., Redfern, J., Williams, E. A., Snowdon, R. L., Modi, P., Hall, M. C. S., Modi, S., Waktare, J. E. P., Mahida, S., Todd, D. M., Mediratta, N. & Gupta, D., 1 May 2019, In: Europace.

Research output: Contribution to journal › Article › peer-review

Open Access

Phosphodiesterase 5 inhibition improves contractile function and restores transverse tubule loss and catecholamine responsiveness in heart failure.

Lawless, M., Caldwell, J., Radcliffe, E., Smith, C., Madders, G., Hutchings, D., Woods, L., Church, S., Unwin, R., Kirkwood, G., Becker, L., Pearman, C., Taylor, R., Eisner, D., Dibb, K. & Trafford, A., 1 May 2019, In: Scientific Reports. 9, 1, 6801.

Research output: Contribution to journal › Article › peer-review

Open Access

2018

Calcium in the Pathophysiology of Atrial Fibrillation and Heart Failure

Denham, N. C., Pearman, C. M., Caldwell, J. L., Madders, G. W. P., Eisner, D. A., Trafford, A. W. & Dibb, K. M., 4 Oct 2018, In: Frontiers in Physiology. 9, OCT, p. 1380 1380.

Research output: Contribution to journal › Article › peer-review

Open Access

Increased vulnerability to atrial fibrillation is associated with increased susceptibility to alternans in old sheep

Pearman, C. M., Madders, G. W. P., Radcliffe, E. J., Kirkwood, G. J., Lawless, M., Watkins, A., Smith, C. E. R., Trafford, A. W., Eisner, D. A. & Dibb, K. M., 4 Dec 2018, In: Journal of the American Heart Association. 7, 23

Research output: Contribution to journal › Article › peer-review

Open Access

Systematic Re-evaluation of SCN5A Variants Associated with Brugada Syndrome

Denham, N. C., Pearman, C. M., Ding, W. Y., Waktare, J., Gupta, D., Snowdon, R., Hall, M., Cooper, R., Modi, S., Todd, D. & Mahida, S., 2018, In: Journal of cardiovascular electrophysiology.

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Open Access

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When you have eliminated the impossible…

Pearman, C. M., Borbas, Z., Wright, D. J. & Modi, S., 2018, In: Pacing and clinical electrophysiology .

Research output: Contribution to journal › Article

Open Access

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2017

Increased Ca buffering underpins remodelling of Ca2+ handling in old sheep atrial myocytes

Clarke, J., Caldwell, J., Pearman, C., Eisner, D., Trafford, A. & Dibb, K., 2017, In: The Journal of Physiology. TJP12537.

Research output: Contribution to journal › Article › peer-review

Open Access

Minimally invasive epicardial surgical ablation alone vs. hybrid ablation for atrial fibrillation: A systematic review and meta-analysis

Pearman, C., Poon, S. S., Bonnett, L. J., Haldar, S., Wong, T., Mediratta, N. & Gupta, D., 11 Dec 2017, In: Arrhythmia and Electrophysiology Review. 6, 4, p. 202-209 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Targeting miR-423-5p Reverses Exercise Training-Induced HCN4 Channel Remodeling and Sinus Bradycardia

D'Souza, A., Pearman, C. M., Wang, Y., Nakao, S., Logantha, S. J. R. J., Cox, C., Bennett, H., Zhang, Y., Johnsen, A. B., Linscheid, N., Poulsen, P. C., Elliott, J., Coulson, J., McPhee, J., Robertson, A., Da Costa Martins, P. A., Kitmitto, A., Wisløff, U., Cartwright, E. J. & Monfredi, O. & 5 others, Lundby, A., Dobrzynski, H., Oceandy, D., Morris, G. M. & Boyett, M. R., 13 Oct 2017, In: Circulation research. 121, 9, p. 1058-1068 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access