Dr Christabel Dube is a neuroscientist with a strong interest in using multi-omic approaches to enhance our understanding of ageing. Her PhD (2018-2022), jointly funded by the A*STAR Institute in Singapore and the University of Manchester's Faculty of Biology, Medicine, and Health, focused on the impact of ageing on myeloid cell behaviour during wound healing. This research employed advanced transcriptomic techniques to investigate how ageing-induced changes in the skin lead to abnormal healing processes. She conducted this work under the supervision of Dr Kimberly A. Mace and Dr Matthew Ronshuagen in Manchester, as well as Dr Chin Yan Lim at the A*STAR Skin Research Labs in Singapore.

After completing her PhD, she joined Dr Stephen Richardson and Prof. Judith Hoyland to contribute to research aimed at characterising phenotypic changes and cell signalling in the human spine throughout development and ageing. Her work integrates multi-omic methodologies to reveal the complex biological processes that underlie age-related changes in the intervertebral disc.

My current project aims to uncover the molecular and cellular changes that occur in intervertebral disc cells throughout the lifespan. By employing multi-omic techniques, I aim to integrate data from genomics, transcriptomics, proteomics, and metabolomics to understand how these cells develop, mature, and eventually degenerate. This research not only deepens our understanding of spinal biology but also has the potential to inform early interventions that could mitigate the impact of ageing on the spine.  Ultimately, I hope to use my experience in multi-omic technologies to advance our understanding of how early-life processes influence ageing within the spine. I want to contribute to research that not only elucidates the fundamental biology of ageing but also translates to new therapeutic strategies to improve health outcomes as we age.

Tutor- MSc in Tissue Engineering for Regenerative Medicine Programme 2023-Present

Graduate Teaching Assistant January 2020- March 2023

Member of  Royal Society of Biology    Jan 2019- Present            

Member of British Society for Matrix Biology   Aug 2023- Present           

Member of ECMage Network   Jan 2023- Present            

Member of the European Macrophage and Dendritic Cell Society   May 2022- May 2023       

Member of the British Society of Immunology  May 2021-May 2023       

Member, Singapore Skin Research Society  Jan 2020- Jan 2022