Christopher Platt

Christopher Platt

Dr

Personal profile

Research interests

I am a Cell Biologist with an interest in normal skin processes and the skin's response to damage. My current research, in collaboration with Walgreens Boots Alliance, focusses on how matrix metalloproteinases (MMPs) mediate damage and repair processes in dermal extracellular matrix (ECM). My previous research includes: developing a 3D cell culture model of a human hair follicle to interrogate signalling processes that regulate hair growth, and identifying the morphological changes in human eyelash follicles at different stages of the hair growth cycle. In addition to academic research, I have worked in biotechnology (Renovo plc) as a Senior Scientist, developing in vitro cell-based models to screen pre-clinical candidates for anti-scarring potential. 

Methodological knowledge

Hair follicle mini-organ culture, 3D spheroid culture, collagen gel contraction assay, fibroblast depleted ECM, gelatin zymography, hydroxyproline assay, collagenase assay, LC-MS/MS, qRT-PCR, frozen sectioning, histology, immunofluorescence, Western blotting. 

Education/Academic qualification

Doctor of Philosophy, Matrix Metalloproteinases in the Sciatic Nerve, University of East Anglia

Award Date: 2 May 2005

Bachelor of Science, Zoology (hons), University of Nottingham

Award Date: 8 May 2000

External positions

Member, British Society for Matrix Biology (BSMB)

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