Christos Pliotas


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Personal profile


Research in my group is focused on elucidating mechanical sensing and response in ion channels. We investigate how ion channels sense forces in membranes and open their pores in response to mechanical stimuli. The main method we employ is Pulsed ELectron-ELectron DOuble Resonance (PELDOR) spectroscopy, (also known as DEER spectroscopy), complemented by Cryo Electron Micrsocopy (cryoEM) and electrophysiology to characterise mechanosensitive ion channels.

We further study the BAM complex, which is an essential membrane protein complex involved in the folding of outer membrane proteins in gram negative bacteria, using in-cell Electron Paramagnetic Resonance (EPR) spectroscopy.

More details about our group, research activities, news and current lab members could be found in the Pliotas Group Research Website

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Doctor of Philosophy, Biochemistry, University of Aberdeen

1 Oct 200731 Jan 2011

Award Date: 6 Jul 2011

Master of Science, Medical Physics, University of Aberdeen

20 Sept 200630 Sept 2007

Award Date: 1 Oct 2007

Bachelor of Science, Physics, National and Kapodistrian University of Athens

Award Date: 6 Jul 2006

External positions

Lecturer in Integrative Membrane Biology, University of Leeds

5 Sept 20188 Jun 2023

Royal Society of Edinburgh Research Fellow & Group Leader, University of St Andrews

1 Jan 20161 Jan 2021

Postdoctoral Research Associate, University of St Andrews

1 Feb 201131 Dec 2015

Research Beacons, Institutes and Platforms

  • Biotechnology
  • Manchester Institute of Biotechnology


  • membrane protein
  • EPR spectroscopy
  • Structural Biology
  • CryoEM
  • Mechanobiology
  • Ion channel
  • Lipids
  • Antimicrobial resistance


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