Christos Tapeinos

Search results

• 2023

  Nanoparticles-based phototherapy systems for cancer treatment: Current status and clinical potential

  Li, J., Wang, S., Fontana, F., Tapeinos, C., Shahbazi, M-A., Han, H. & Santos, HA., May 2023, In: Bioactive Materials. 23, p. 471-507 37 p.

  Research output: Contribution to journal › Review article › peer-review

• Nanoparticles-based phototherapy systems for cancer treatment: Current status and clinical potential

  Li, J., Wang, S., Fontana, F., Tapeinos, C., Shahbazi, M-A., Han, H. & Santos, H. A., May 2023, In: Bioactive Materials.

  Research output: Contribution to journal › Review article › peer-review

• Self-assembled three-dimensional hydrogels based on graphene derivatives and cerium oxide nanoparticles: scaffolds for co-culture of oligodendrocytes and neurons derived from neural stem cells

  Polo, Y., Luzuriaga, J., Langarica, S. G. D., Pardo-Rodríguez, B., Martínez-Tong, D. E., Tapeinos, C., Manero-Roig, I., Marin, E., Muñoz-Ugartemendia, J., Ciofani, G., Ibarretxe, G., Unda, F., Sarasua, J-R., Pineda, J. R. & Larrañaga, A., 8 Feb 2023, In: Nanoscale.

  Research output: Contribution to journal › Article › peer-review
• 2022

  Cerium oxide nanoparticles administration during machine perfusion of discarded human livers: A pilot study

  Del Turco, S., Cappello, V., Tapeinos, C., Moscardini, A., Sabatino, L., Battaglini, M., Melandro, F., Torri, F., Martinelli, C., Babboni, S., Silvestrini, B., Morganti, R., Gemmi, M., De Simone, P., Martins, P. N., Crocetti, L., Peris, A., Campani, D., Basta, G., Ciofani, G., & 1 othersGhinolfi, D., 1 Jul 2022, In: Liver Transplantation. 28, 7, p. 1173-1185 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Perfusion 100%
  • Electron Microscopy 100%
  • Liver 66%
  • Antioxidant 50%
  • Mitochondrial DNA 50%

• Combining confocal microscopy, dSTORM, and mass spectroscopy to unveil the evolution of the protein corona associated with nanostructured lipid carriers during blood–brain barrier crossing

  Battaglini, M., Feiner, N., Tapeinos, C., Pasquale, D. D., Pucci, C., Marino, A., Bartolucci, M., Petretto, A., Albertazzi, L. & Ciofani, G., 22 Sep 2022, In: Nanoscale. 14, 36, p. 13292-13307 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Protein 100%
  • Nanomaterial 33%
  • Blood Brain Barrier 26%
  • Evolution 20%
  • Lipid 20%

• Exploiting the layer-by-layer nanoarchitectonics for the fabrication of polymer capsules: A toolbox to provide multifunctional properties to target complex pathologies

  Marin, E., Tapeinos, C., Sarasua, J. R. & Larranaga, A., Jun 2022, In: Advances in Colloid and Interface Science.

  Research output: Contribution to journal › Review article › peer-review

  • Capsule 100%
  • Polymer 44%
  • Biomaterial 11%
  • Diagnostic Agent 11%

• Innovative nanotechnology tools for the functional control and tracking of human stem cells

  Marino, A., Battaglini, M., Tapeinos, C., Larrañaga, A. & Ciofani, G., 1 Dec 2022, In: Materials Today Advances. 16, 100298.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Stem Cell 100%
  • Tissues 40%
  • Regenerative Medicine 40%
  • Development 20%
  • Differentiation 20%

• Progress in Stimuli-Responsive Biomaterials for Treating Cardiovascular and Cerebrovascular Diseases

  Tapeinos, C., Gao, H., Bauleth-Ramos, T. & Santos, H. A., 2022, In: Small.

  Research output: Contribution to journal › Review article › peer-review
• 2021

  Graphene‐Based Nanotechnology in Neurodegenerative Disorders

  Tapeinos, C., Mar 2021, In: Advanced NanoBiomed Research.

  Research output: Contribution to journal › Review article › peer-review

• Non-viral nanoparticles for RNA interference: Principles of design and practical guidelines

  Liu, Z., Wang, S., Tapeinos, C., Torrieri, G., Känkänen, V., El-Sayed, N., Python, A., Hirvonen, J. T. & Santos, H. A., Jul 2021, In: Advanced Drug Delivery Reviews.

  Research output: Contribution to journal › Review article › peer-review
• 2020

  Advanced Functional Materials and Cell‐Based Therapies for the Treatment of Ischemic Stroke and Postischemic Stroke Effects

  Tapeinos, C., Larrañaga, A., Tomatis, F., Bizeau, J., Marino, A., Battaglini, M., Pandit, A. & Ciofani, G., 3 Jan 2020, In: Advanced Functional Materials. 30, 1, 22 p.

  Research output: Contribution to journal › Review article › peer-review

  • Ischemic Stroke 100%
  • Ischemia 66%
  • Stroke 33%
  • Brain 33%
  • Nervous System Disorder 33%

• Advanced Theranostic Nanomedicine in Oncology

  Tapeinos, C., Marino, A. & Ciofani, G., 25 Feb 2020, In: Frontiers in Bioengineering and Biotechnology. 2 p.

  Research output: Contribution to journal › Editorial

  • Oncology 100%
  • Nanomedicine 50%
  • Malignant Neoplasm 25%
  • Awareness 25%
  • Biocompatible Material 25%

• Encapsulation of manganese dioxide nanoparticles into layer-by-layer polymer capsules for the fabrication of antioxidant microreactors

  Marin, E., Tapeinos, C., Lauciello, S., Ciofani, G., Sarasua, J. R. & Larrañaga, A., Dec 2020, In: Materials Science and Engineering C. 117, p. 1-11 11 p., 111349.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Antioxidant Agent 100%
  • Reactive Oxygen Species 100%
  • Antioxidant 100%
  • Polymer 80%
  • Oxidative Stress 80%

• Homotypic targeting and drug delivery in glioblastoma cells through cell membrane-coated boron nitride nanotubes

  Pasquale, D. D., Marino, A., Tapeinos, C., Pucci, C., Rocchiccioli, S., Michelucci, E., Finamore, F., McDonnell, L., Scarpellini, A., Lauciello, S., Prato, M., Larrañaga, A., Drago, F. & Ciofani, G., Jul 2020, In: Materials & Design. 192, p. 1-21 21 p., 108742.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glioblastoma 100%
  • Glioblastoma Multiforme 83%
  • Cell Membrane 83%
  • Boron Nitride Nanotube 66%
  • Recognition 50%

• Polydopamine Nanoparticles as an Organic and Biodegradable Multitasking Tool for Neuroprotection and Remote Neuronal Stimulation

  Battaglini, M., Marino, A., Carmignani, A., Tapeinos, C., Cauda, V., Ancona, A., Garino, N., Vighetto, V., Rosa, G. L., Sinibaldi, E. & Ciofani, G., 12 Aug 2020, In: ACS applied materials & interfaces. 12, 32, p. 35782–35798 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Lipid 100%
  • Reactive Oxygen Species 50%
  • Neuron 50%
  • Oxidative Stress 25%
  • Neuroprotective Agent 25%

• Smart diagnostic nano-agents for cerebral ischemia

  Tapeinos, C., Battaglini, M., Marino, A. & Ciofani, G., 7 Aug 2020, In: Journal of Materials Chemistry B. 8, 29, p. 6233-6251 19 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Brain Ischemia 100%
  • Patient 50%
  • Diagnosis 50%
  • Brain 50%
  • Ischemia 50%
• 2019

  Cell Membrane‐Coated Magnetic Nanocubes with a Homotypic Targeting Ability Increase Intracellular Temperature due to ROS Scavenging and Act as a Versatile Theranostic System for Glioblastoma Multiforme

  Tapeinos, C., Tomatis, F., Battaglini, M., Larrañaga, A., Marino, A., Telleria, I. A., Angelakeris, M., Debellis, D., Drago, F., Brero, F., Arosio, P., Lascialfari, A., Petretto, A., Sinibaldi, E. & Ciofani, G., 7 Sep 2019, In: Advanced Healthcare Materials. 8, 18, p. 1-19 19 p., 1900612.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Aptitude 100%
  • Magnetic Field 66%
  • Temperature 66%
  • Sorafenib 66%
  • Hydrogen Peroxide 66%

• Design, Fabrication, and in Vitro Evaluation of Nanoceria-Loaded Nanostructured Lipid Carriers for the Treatment of Neurological Diseases

  Battaglini, M., Tapeinos, C., Cavaliere, I., Marino, A., Ancona, A., Garino, N., Cauda, V., Palazon, F., Debellis, D. & Ciofani, G., 11 Feb 2019, In: ACS Biomaterials Science and Engineering. 5, 2, p. 670–682 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Lipid 100%
  • Antioxidant 66%
  • Antioxidant Agent 66%
  • Blood-Brain Barrier 50%
  • Blood Brain Barrier 50%

• Multifunctional temozolomide-loaded lipid superparamagnetic nanovectors: Dual targeting and disintegration of glioblastoma spheroids by synergic chemotherapy and hyperthermia treatment

  Marino, A., Camponovo, A., Degl'Innocenti, A., Bartolucci, M., Tapeinos, C., Martinelli, C., De Pasquale, D., Santoro, F., Mollo, V., Arai, S., Suzuki, M., Harada, Y., Petretto, A. & Ciofani, G., 28 Nov 2019, In: Nanoscale. 11, 44, p. 21227-21248 22 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hyperthermia 100%
  • Malignant Neoplasm 75%
  • Glioblastoma 75%
  • Lipid 50%
  • Temozolomide 50%

• Piezoelectric barium titanate nanostimulators for the treatment of glioblastoma multiforme

  Marino, A., Almici, E., Migliorin, S., Tapeinos, C., Battaglini, M., Cappello, V., Marchetti, M., de Vito, G., Cicchi, R., Pavone, F. S. & Ciofani, G., 7 Mar 2019, In: Journal of Colloid and Interface Science. 538, p. 449-461 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Cells 100%
  • Glioblastoma 80%
  • Therapeutic Procedure 60%
  • Electro Stimulation 40%
  • Nanoparticle 40%

• Stimuli-responsive lipid-based magnetic nanovectors increase apoptosis in glioblastoma cells through synergic intracellular hyperthermia and chemotherapy

  Tapeinos, C., Marino, A., Battaglini, M., Migliorin, S., Brescia, R., Scarpellini, A., De Julián Fernández, C., Prato, M., Drago, F. & Ciofani, G., 7 Jan 2019, In: Nanoscale. 11, 1, p. 72-88 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cells 100%
  • Hyperthermia 80%
  • Magnetism 80%
  • Lipid 60%
  • Glioblastoma 60%
• 2018

  CeO2 Nanoparticles-Loaded pH-Responsive Microparticles with Antitumoral Properties as Therapeutic Modulators for Osteosarcoma

  Tapeinos, C., Battaglini, M., Prato, M., Rosa, G. L., Scarpellini, A. & Ciofani, G., 31 Aug 2018, In: ACS Omega. 3, 8, p. 8952–8962 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Osteosarcoma 100%
  • Microparticle 100%
  • Doxorubicin 100%
  • Cerium Oxide Nanoparticle 75%
  • Neoplasm 25%

• Functionalised collagen spheres reduce H₂O₂ mediated apoptosis by scavenging overexpressed ROS

  Tapeinos, C., Larrañaga, A., Sarasua, J-R. & Pandit, A., Oct 2018, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 14, 7, p. 2397-2405 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Reactive Oxygen Species 100%
  • Reactive Oxygen Metabolite 100%
  • Species 100%
  • Cells 75%
  • Oxidative Stress 75%

• Magnetic Nanoparticles and Their Bioapplications

  Tapeinos, C., 15 May 2018, Smart Nanoparticles for Biomedicine. Ciofani, G. (ed.). Amsterdam, Netherlands: Elsevier Masson s.r.l., p. 131-142 12 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Magnetism 100%
  • Magnetic Nanoparticle 71%
  • Synthesis 14%
  • Surface Property 14%
  • Functionalisation 14%

• Scavenging Nanoreactors that Modulate Inflammation

  Pereira, D. R., Tapeinos, C., Rebelo, A. L., Oliveira, J. M., Reis, R. L. & Pandit, A., Jun 2018, In: Advanced Biosystems. 2, 6, p. 1-13 13 p., 1800086.

  Research output: Contribution to journal › Article › peer-review

  • Reactive Oxygen Species 100%
  • Nanoreactors 41%
  • Oxidative Stress 33%
  • Serositis 33%
  • Tissues 33%
• 2017

  Advances in the design of solid lipid nanoparticles and nanostructured lipid carriers for targeting brain diseases

  Tapeinos, C., Battaglini, M. & Ciofani, G., 28 Oct 2017, In: Journal of Controlled Release. 264, 28, p. 306-332 27 p.

  Research output: Contribution to journal › Review article › peer-review

  • Lipid 100%
  • Solid Lipid Nanoparticle 100%
  • Brain Cancer 40%
  • Brain Disease 40%
  • Multiple Sclerosis 20%

• Smart materials meet multifunctional biomedical devices: Current and prospective implications for nanomedicine

  Genchi, G. G., Marino, A., Tapeinos, C. & Ciofani, G., 18 Dec 2017, In: Frontiers in Bioengineering and Biotechnology. 5, 8 p., 80.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Devices 100%
  • Development 50%
  • Nanomedicine 50%
  • Drug Delivery 50%
  • Intelligent Material 50%

• Synthesis and characterization of hyaluronic acid coated manganese dioxide microparticles that act as ROS scavengers

  Bizeau, J., Tapeinos, C., Marella, C., Larrañaga, A. & Pandit, A., 1 Nov 2017, In: Colloids and Surfaces B: Biointerfaces. 159, p. 30-38 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Microparticle 100%
  • Therapeutic Procedure 13%
  • Hydrogen Peroxide 13%
  • Concentration 10%
  • Environment 6%
• 2016

  An acetal-based polymeric crosslinker with controlled pH-sensitivity

  Cao, H., Dong, Y., Bre, L., Tapeinos, C., Wang, W. & Pandit, A., 15 Jan 2016, In: RSC Adv.. 12, p. 9604-9611 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Acetal 100%
  • Hydrogel 83%
  • Collagen 83%
  • Polymer 66%
  • Poly(ethylene Glycol) 33%

• Physical, Chemical, and Biological Structures based on ROS-Sensitive Moieties that are Able to Respond to Oxidative Microenvironments

  Tapeinos, C. & Pandit, A., 20 Jul 2016, In: Advanced Materials. 28, 27, p. 5553-5585 32 p.

  Research output: Contribution to journal › Review article › peer-review

  • Reactive Oxygen Species 100%
  • Species 100%
  • Reactive Oxygen Metabolite 100%
  • Number 60%
  • Procedure 40%

• Reactive Oxygen Species: Physical, Chemical, and Biological Structures based on ROS-Sensitive Moieties that are Able to Respond to Oxidative Microenvironments (Adv. Mater. 27/2016)

  Tapeinos, C. & Pandit, A., 2016

  Research output: Non-textual form › Design

• Sustained release profile of quatro stimuli nanocontainers as a multi sensitive vehicle exploiting cancer characteristics

  Tapeinos, C., Efthimiadou, E. K., Boukos, N. & Kordas, G., 1 Dec 2016, In: Colloids and Surfaces B: Biointerfaces. 148, p. 95-103 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Monomer 100%
  • Polymerization 50%
  • Emulsion Polymerization 50%
  • Coating 33%
  • Magnetic Fields 33%
• 2014

  Dynamic in vivo imaging of dual-triggered microspheres for sustained release applications: Synthesis, characterization and cytotoxicity study

  Efthimiadou, E. K., Tapeinos, C., Chatzipavlidis, A., Boukos, N., Fragogeorgi, E., Palamaris, L., Loudos, G. & Kordas, G., 30 Jan 2014, In: International Journal of Pharmaceutics. 461, 1-2, p. 54-63 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Microsphere 100%
  • Hyperthermia 16%
  • Doxorubicin 16%
  • Controlled Release 16%
  • Acrylate 16%

• PH- and thermo-responsive microcontainers as potential drug delivery systems: Morphological characteristic, release and cytotoxicity studies

  Efthimiadou, E. K., Tapeinos, C., Tziveleka, L-A., Boukos, N. & Kordas, G., 1 Apr 2014, In: Materials Science and Engineering C. 37, 1, p. 271-277 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Drug 100%
  • Drug Delivery System 75%
  • Malignant Neoplasm 50%
  • Poly(methyl Methacrylate) 50%
  • Cytotoxicity 50%
• 2013

  Microspheres as therapeutic delivery agents: Synthesis and biological evaluation of pH responsiveness

  Tapeinos, C., Efthimiadou, E. K., Boukos, N., Charitidis, C. A., Koklioti, M. & Kordas, G., 14 Jan 2013, In: Journal of Materials Chemistry B. 1, 2, p. 194-203 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Procedure 100%
  • Microsphere 100%
  • Coating Agent 66%
  • Synthesis (Chemical) 66%
  • Emulsion Polymerization 66%
• 2011

  New approach in synthesis, characterization and release study of pH-sensitive polymeric micelles, based on PLA-Lys-b-PEGm, conjugated with doxorubicin

  Efthimiadou, E. K., Tapeinos, C., Bilalis, P. & Kordas, G., 25 Sep 2011, In: Journal of Nanoparticle Research. 13, 12, p. 6725-6736 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Synthesis (Chemical) 100%
  • Synthesis 100%
  • Spectroscopy 60%
  • Thermogravimetric Analysis 60%
  • Block Copolymer 60%

• Smart Nanoparticles as new Drug Delivery Systems: Bioapplications

  Efthimiadou, EK., Bilalis, P., Kordas, GK., Chatzipavlidis, A. & Tapeinos, CG., Aug 2011, In: Planta Medica. 77, 12

  Research output: Contribution to journal › Conference article

  • Polymer 100%
  • Nanosphere 100%
  • Polymerization 100%
  • X-Ray Diffraction 75%
  • Magnetism 75%
• 2008

  Synthesis and characterization of magnetic nanocontainers

  Tapeinos, C., Kartsonakis, I., Liatsi, P., Daniilidis, I. & Kordas, G., 2 Apr 2008, In: Journal of the American Ceramic Society. 91, 4, p. 1052-1056 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Sphere 100%
  • Polystyrene 62%
  • Sample 25%
  • Procedure 25%
  • Reaction Temperature 25%