Research output per year
Research output per year
Personal profile
Overview
Receiving my PhD in 2009, I started my career as a data scientist in cancer research, where the ever-increasing volume and complexity in clinical data calls for novel data analytical approaches to meet the unmet need for personalized precision therapy. I worked as a lecturer in biomarker statistics in the University of Manchester from 2014-2018, before I joined the newly established Manchester Centre for Cancer Biomarker Sciences as the lead biostatistician.
My research focused on developing and applying novel statistical methods to identify innovative biomarkers that help deliver personalized therapy in cancer diagnosis and treatment. My current researches include: (1) developing novel Bayesian methods for joint modelling of longitudinal and time-to-event data, to identify biomarkers that predict treatment response and resistance (2) using machine learning approaches to predict cancer treatment outcome via single cell sequencing data (3) designing clinical trials and translational biomarker studies on novel cancer drugs.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Beacons, Institutes and Platforms
- Digital Futures
- Institute for Data Science and AI
Keywords
- Biostatistics
- Bioinformatics
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Network
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c-MET/VEGFR-2 co-localisation impacts on survival following bevacizumab therapy in epithelial ovarian cancer: an exploratory biomarker study of ICON7
Morgan, R., Ferreras, C., Peset Martin, I., Avizienyte, E., Renehan, A., Edmondson, R., Murphy, A., Nicum, S., Van Brussel, T., Clamp, A., Lambrechts, D., Zhou, C. & Jayson, G., 1 Feb 2022, In: BMC Medicine. 20, 59.Research output: Contribution to journal › Article › peer-review
Open Access -
Establishment of CORONET; COVID-19 Risk in Oncology Evaluation Tool to identify cancer patients at low versus high risk of severe complications of COVID-19 infection upon presentation to hospital
Lee, R., Wysocki, O., Zhou, C., Shotton, R., Tivey, A., Lever, L., Woodcock, J., Banfill, K., Britton, F., Graham, D., Hague, C., Cooksley, T., Freitas, A. & Armstrong, A., 10 Mar 2022, (Accepted/In press) In: JCO Clinical Cancer Informatics.Research output: Contribution to journal › Article › peer-review
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Plasma Tie2 trajectories identify vascular response criteria for VEGF inhibitors across advanced biliary tract, colorectal and ovarian cancers
Zhou, C., O'Connor, J., Backen, A., Valle, J., Bridgewater, J. A., Dive, C. & Jayson, G., 1 Apr 2022, In: ESMO Open. 7, 2, 100417.Research output: Contribution to journal › Article › peer-review
Open Access -
Real-world outcomes with ipilimumab and nivolumab in advanced melanoma: a multicentre retrospective study
Serra-Bellver, P., Versluis, J. M., Oberoi, H. K., Zhou, C., Slattery, T. D., Khan, Y., Patrinely, J. R., Pires da Silva, I., Martínez-Vila, C., Cook, N., Graham, D. M., Carlino, M. S., Menzies, A. M., Arance, A. M., Johnson, D. B., Long, G. V., Pickering, L., Larkin, J. M. G., Blank, C. U. & Lorigan, P., 8 Sep 2022, (Accepted/In press) In: European Journal of Cancer.Research output: Contribution to journal › Article › peer-review
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Antibiotic use reduces efficacy of tyrosine kinase inhibitors in patients with advanced melanoma and non-small cell lung cancer.
Tinsley, N., Cook, N., Zhou, C., Nahm, S. H-E., Rack, S., Tan, G. C. L., Lorigan, P. & Blackhall, F. H., 20 May 2021, In: Journal of Clinical Oncology. 39, 15_suppl, p. 3100-3100 1 p.Research output: Contribution to journal › Article › peer-review
Datasets
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Plasma Tie2 is a Tumor Vascular Response Biomarker for VEGF Inhibitors
Zhou, C. (Creator) & Jayson, G. (Contributor), Mendeley Data, 3 Oct 2018
DOI: 10.17632/xcsbspcghg.2, https://data.mendeley.com/datasets/xcsbspcghg
Dataset