Research output per year
Research output per year
Personal profile
Biography
I am Professor of Cell Biology and Director of the Wellcome Trust Centre for Cell-Matrix Research. I am also a founding member of the Manchester Breast Centre and the Breakthrough Research Unit in Manchester. My biography can be found on: http://www.wellcome-matrix.org/research-groups/research-group-1/charles-streuli.html
Research interests
The research in our laboratory is focussed on how cell-matrix interactions control the development and function of epithelial cells. We study the mammary gland becasue it is an excellent system to uncover basic principles of cell and developmental biology. Understanding how normal mammary epithelial cells work is revealing new targets and pathways for treating breast cancer.
For full details of our research programme, current projects, publications, vacancies, please visit: http://www.wellcome-matrix.org/research-groups/research-group-1/charles-streuli.html
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells
Chen, F., Gurler, S. B., Novo, D., Selli, C., Alferez, D. G., Eroglu, S., Pavlou, K., Zhang, J., Sims, A. H., Humphreys, N. E., Adamson, A., Campbell, A., Sansom, O. J., Tournier, C., Clarke, R. B., Brennan, K., Streuli, C. H. & Ucar, A., 24 Feb 2023, In: Oncogene. 42, p. 679-692 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Elevated EDAR signalling promotes mammary gland tumourigenesis with squamous metaplasia
Williams, R., Jobling, S., Sims, A. H., Mou, C., Wilkinson, L., Collu, G. M., Streuli, C., Gilmore, A., Headon, D. J. & Brennan, K., 9 Jun 2021, (Accepted/In press) In: Oncogene.Research output: Contribution to journal › Article › peer-review
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Vinculins interaction with talin is essential for mammary epithelial differentiation.
Wang, P., Wu, J., Wood, A., Jones, M., Pedley, R., Li, W., Ross, R., Ballestrem, C., Gilmore, A. & Streuli, C., 2020, In: Scientific Reports. 9, 18400.Research output: Contribution to journal › Article › peer-review
Open Access -
Influence of the extracellular matrix on cell-intrinsic circadian clocks
Streuli, C. H. & Meng, Q.-J., 1 Feb 2019, In: Journal of Cell Science.Research output: Contribution to journal › Article › peer-review
Open Access -
Epithelial and stromal circadian clocks are inversely regulated by their mechanomatrix environment
Williams, J., Yang, N., Wood, A., Zindy, E., Meng, Q.-J. & Streuli, C., 6 Mar 2018, In: Journal of Cell Science.Research output: Contribution to journal › Article › peer-review
Open Access
Activities
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EMBO polarity conference
Charles Streuli (Discussant)
2017Activity: Talk or presentation › Invited talk › Research
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Fibronectin & Integrin Gordon Research Conference
Charles Streuli (Chair)
2017Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc › Research
Datasets
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Increased peri-ductal collagen micro-organization may contribute to raised mammographic density
Mcconnell, J. (Contributor), O’Connell, O. (Contributor), Brennan, K. (Contributor), Weiping, L. (Contributor), Howe, M. (Contributor), Joseph, L. (Contributor), Knight, D. (Contributor), O'Cualain, R. (Contributor), Lim, Y. (Contributor), Leek, A. (Contributor), Waddington, R. (Contributor), Rogan, J. (Contributor), Astley, S. (Contributor), Gandhi, A. (Contributor), Kirwan, C. (Contributor), Sherratt, M. (Contributor) & Streuli, C. (Contributor), figshare , 8 Jan 2016
DOI: 10.6084/m9.figshare.c.3618407.v1, https://figshare.com/collections/Increased_peri-ductal_collagen_micro-organization_may_contribute_to_raised_mammographic_density/3618407/1
Dataset