Research output per year
Research output per year
- 1 - 50 out of 132 results
Search results
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2023
RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells
Chen, F., Gurler, S. B., Novo, D., Selli, C., Alferez, D. G., Eroglu, S., Pavlou, K., Zhang, J., Sims, A. H., Humphreys, N. E., Adamson, A., Campbell, A., Sansom, O. J., Tournier, C., Clarke, R. B., Brennan, K., Streuli, C. H. & Ucar, A., 24 Feb 2023, In: Oncogene. 42, p. 679-692 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Elevated EDAR signalling promotes mammary gland tumourigenesis with squamous metaplasia
Williams, R., Jobling, S., Sims, A. H., Mou, C., Wilkinson, L., Collu, G. M., Streuli, C., Gilmore, A., Headon, D. J. & Brennan, K., 9 Jun 2021, (Accepted/In press) In: Oncogene.Research output: Contribution to journal › Article › peer-review
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2020
Vinculins interaction with talin is essential for mammary epithelial differentiation.
Wang, P., Wu, J., Wood, A., Jones, M., Pedley, R., Li, W., Ross, R., Ballestrem, C., Gilmore, A. & Streuli, C., 2020, In: Scientific Reports. 9, 18400.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Influence of the extracellular matrix on cell-intrinsic circadian clocks
Streuli, C. H. & Meng, Q.-J., 1 Feb 2019, In: Journal of Cell Science.Research output: Contribution to journal › Article › peer-review
Open Access -
2018
Epithelial and stromal circadian clocks are inversely regulated by their mechanomatrix environment
Williams, J., Yang, N., Wood, A., Zindy, E., Meng, Q.-J. & Streuli, C., 6 Mar 2018, In: Journal of Cell Science.Research output: Contribution to journal › Article › peer-review
Open Access -
Integrin-Rac signalling for mammary epithelial stem cell self-renewal
Olabi, S., Ucar, A., Brennan, K. & Streuli, C. H., 2018, In: Breast Cancer Research. 20, 1Research output: Contribution to journal › Article › peer-review
Open Access -
2017
Cellular mechano-environment regulates the mammary circadian clock
Yang, N., Williams, J., Pekovic-Vaughan, V., Wang, P., Olabi, S., McConnell, J., Gossan, N., Hughes, A., Cheung, J., Streuli, C. H. & Meng, Q.-J., 30 Jan 2017, In: Nature Communications. 8, p. 14287Research output: Contribution to journal › Article › peer-review
Open Access -
Extracellular matrix promotes clathrin-dependent endocytosis of prolactin and STAT5 activation in differentiating mammary epithelial cells
Bridgewater, R., Streuli, C. & Caswell, P., 2017, In: Scientific Reports. 7, 4572.Research output: Contribution to journal › Article › peer-review
Open Access -
The requirement of integrins for breast epithelial proliferation
Moreno Layseca, P., Ucar, A., Sun, H., Wood, A., Olabi, S., Gilmore, A., Brennan, K. & Streuli, C., 2017, In: European journal of cell biology.Research output: Contribution to journal › Article › peer-review
Open AccessFile325 Downloads (Pure) -
2016
3D cell bioprinting of self-assembling peptide-based hydrogels
Raphael, B., Khalil, T., Workman, V. L., Smith, A., Brown, C. P., Streuli, C., Saiani, A. & Domingos, M., 31 Dec 2016, In: Materials Letters. 190, p. 103-106Research output: Contribution to journal › Article › peer-review
Open AccessFile898 Downloads (Pure) -
Cellular microenvironment controls the nuclear architecture of breast epithelia through β1-integrin
Maya-Mendoza, A., Bartek, J., Jackson, D. & Streuli, C., 2016, In: Cell Cycle. 15, 3, p. 345-356 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Circadian clocks and breast cancer
Blakeman, V., Williams, J., Meng, Q.-J. & Streuli, C. H., 2016, In: Breast Cancer Research. 18, 1, 9 p., 89.Research output: Contribution to journal › Article › peer-review
Open Access -
Increased peri-ductal collagen micro-organization may contribute to raised mammographic density
Mcconnell, J., O'Connell, O. V., Brennan, K., Weiping, L., Howe, M., Joseph, L., Knight, D., O'Cualain, R., Lim, Y., Leek, A., Waddington, R., Rogan, J., Gandhi, A., Astley, S., Gandhi, A., Kirwan, C., Streuli, C., Sherratt, M. & Streuli, C., 8 Jan 2016, In: Breast Cancer Research. 18, 5.Research output: Contribution to journal › Article › peer-review
Open Access11 Downloads (Pure) -
Integrin α4β1 controls G9a activity that regulates epigenetic changes and nuclear properties required for lymphocyte migration.
Zhang, X., Cook, P., Zindy, E., Williams, W., Jowitt, T., Streuli, C., MacDonald, A. & Redondo-Munoz, J., 20 Apr 2016, In: Nucleic acids research. 44, 7, p. 3031-3044 4 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Oncogenic activation of FAK drives apoptosis suppression in a 3D-culture model of breast cancer initiation
Walker, S., Foster, F., Wood, A., Owens, T., Brennan, K., Streuli, C. & Gilmore, A., 6 Sept 2016, In: Oncotarget.Research output: Contribution to journal › Article › peer-review
Open Access -
PAK proteins and YAP-1 signalling downstream of integrin beta-1 myofibroblasts promote liver fibrosis
Martin, K., Pritchett, J., Llewellyn, J., Mullan, A., Athwal, V., Dobie, R., Harvey, E., Zeef, L., Farrow, S., Streuli, C., Henderson, N., Friedman, S., Hanley, N. & Piper Hanley, K., 18 Aug 2016, In: Nature Communications. 7, 12502.Research output: Contribution to journal › Article › peer-review
Open Access -
Rac1 Controls Both the Secretory Function of the Mammary Gland and Its Remodeling for Successive Gestations
Akhtar, N., Li, W., Mironov, A. & Streuli, C., 12 Sept 2016, In: Developmental cell. 38, 5, p. 522-535 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Raised mammographic density: Causative mechanisms and biological consequences
Sherratt, M. J., McConnell, J. C. & Streuli, C. H., 3 May 2016, In: Breast Cancer Research. 18, 1, 45.Research output: Contribution to journal › Article › peer-review
Open Access -
SPRY1 regulates mammary epithelial morphogenesis by modulating EGFR-dependent stromal paracrine signaling and ECM remodeling
Koledova, Z., Zhang, X., Streuli, C., Clarke, R. B., Klein, O. D., Werb, Z. & Lu, P., 12 Sept 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 39, p. E5731-E5740Research output: Contribution to journal › Article › peer-review
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The Integrin-Mediated ILK-Parvin-αPix Signalling Axis Controls Differentiation in Mammary Epithelial Cells
Rooney, N., Wang, P., Brennan, K., Gilmore, A. & Streuli, C., 2016, In: Journal of Cellular Physiology. 231, 11, p. 2408-2417Research output: Contribution to journal › Article › peer-review
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2015
The MEF2-HDAC axis controls proliferation of mammary epithelial cells and acini formation in vitro
Clocchiatti, A., DiGiorgio, E., Viviani, G., Streuli, C., Sgorbissa, A., Picco, R., Cutano, V. & Brancolini, C., 2015, In: Journal of Cell Science. 2, 12, p. 1354-1363 9 p., bio.20136007.Research output: Contribution to journal › Article › peer-review
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2014
A role for β3-integrins in linking breast development and cancer
Ucar, A. & Streuli, C. H., 2014, In: Developmental cell. 30, 3, p. 251-252 2 p.Research output: Contribution to journal › Article › peer-review
Open Access -
FGF ligands of the postnatal mammary stroma regulate distinct aspects of epithelial morphogenesis
Zhang, X., Martinez, D., Koledova, Z., Qiao, G., Streuli, C. & Lu, P., 2014, In: Development (Cambridge). 141, p. 3352-3362 11 p.Research output: Contribution to journal › Article › peer-review
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Immortalised breast epithelia survive prolonged DNA replication stress and return to cycle from a senescent-like state
Maya-Mendoza, A., Merchut-Maya, J., Bartkova, J., Bartek, J., Streuli, C. & Jackson, D., Jul 2014, In: CELL DEATH & DISEASE. 5, 13 p., e1351.Research output: Contribution to journal › Article › peer-review
Open Access -
Integrins and epithelial cell polarity
Lee, J. & Streuli, C., 2014, In: Journal of Cell Science. 127, p. 3217-3225 9 p.Research output: Contribution to journal › Article › peer-review
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Phosphorylation of the Proapoptotic BH3-Only Protein Bid Primes Mitochondria for Apoptosis during Mitotic Arrest
Wang, P., Lindsay, J., Owens, T. W., Mularczyk, E. J., Warwood, S., Foster, F., Streuli, C. H., Brennan, K. & Gilmore, A. P., 2014, In: Cell Reports. 7, 3, p. 661-671 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Signalling pathways linking integrins with cell cycle progression
Moreno Layseca, P. & Streuli, C., 2014, In: Matrix Biology. 34, p. 144-153 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2013
An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epithelium
Akhtar, N. & Streuli, C. H., Jan 2013, In: Nature Cell Biology. 15, 1, p. 17-27 10 p.Research output: Contribution to journal › Article › peer-review
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Bax Exists in a Dynamic Equilibrium between the Cytosol and Mitochondria to Control Apoptotic Priming
Schellenberg, B., Wang, P., Keeble, J. A., Rodriguez-Enriquez, R., Walker, S., Owens, T. W., Foster, F., Tanianis-Hughes, J., Brennan, K., Streuli, C. H. & Gilmore, A. P., 7 Mar 2013, In: Molecular Cell. 49, 5, p. 959-971 12 p.Research output: Contribution to journal › Article › peer-review
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Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
Eccles, S. A., Aboagye, E. O., Ali, S., Anderson, A. S., Armes, J., Berditchevski, F., Blaydes, J. P., Brennan, K., Brown, N. J., Bryant, H. E., Bundred, N. J., Burchell, J. M., Campbell, A. M., Carroll, J. S., Clarke, R., Coles, C. E., Cook, G. J. R., Cox, A., Curtin, N. J. & Dekker, L. V. & 67 others, , 1 Oct 2013, In: Breast Cancer Research. 15, 5, R92.Research output: Contribution to journal › Article › peer-review
Open Access -
How integrins control breast biology
Glukhova, M. A. & Streuli, C. H., Oct 2013, In: Current opinion in cell biology. 25, 5, p. 633-641 8 p.Research output: Contribution to journal › Article › peer-review
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Inhibitor of Apoptosis proteins: promising targets for cancer therapy
Owens, T., Gilmore, A., Streuli, C. & Foster, F., May 2013, In: Journal of Carcinogenesis and Mutagenesis.Research output: Contribution to journal › Article › peer-review
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2012
Prenatal period of life as a matrix for our lives and our societies
Streuli, C. & Janus, L., Mar 2012, In: Journal of Psychohistory. 39, 4, p. 291-305 14 p.Research output: Contribution to journal › Article › peer-review
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Specific β-containing integrins exert differential control on proliferation and 2D collective cell migration in mammary epithelial cells
Jeanes, A., Wang, P., Moreno-Layseca, P., Paul, N., Cheung, J., Tsang, R., Akhtar, N., Foster, F., Brennan, K. & Streuli, C., 2012, In: Journal of Biological Chemistry. 287, p. 24103-24112Research output: Contribution to journal › Article › peer-review
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Specific β-containing integrins exert differential control on proliferation and two-dimensional collective cell migration in mammary epithelial cells
Jeanes, A. I., Wang, P., Moreno-Layseca, P., Paul, N., Cheung, J., Tsang, R., Akhtar, N., Foster, F. M., Brennan, K. & Streuli, C. H., 13 Jul 2012, In: Journal of Biological Chemistry. 287, 29, p. 24103-24112 9 p.Research output: Contribution to journal › Article › peer-review
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The RhoA-Rok-myosin II pathway is involved in extracellular matrix-mediated regulation of prolactin signaling in mammary epithelial cells
Du, J. Y., Chen, M. C., Hsu, T. C., Wang, J. H., Brackenbury, L., Lin, T. H., Wu, Y. Y., Yang, Z., Streuli, C. H. & Lee, Y. J., Apr 2012, In: Journal of Cellular Physiology. 227, 4, p. 1553-1560 7 p.Research output: Contribution to journal › Article › peer-review
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2011
Cellular microenvironment influences the ability of mammary epithelia to undergo cell cycle
Jeanes, A. I., Maya-Mendoza, A. & Streuli, C. H., 2011, In: PLoS ONE. 6, 3, e18144.Research output: Contribution to journal › Article › peer-review
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How integrins control mammary epithelial differentiation: A possible role for the ILK-PINCH-Parvin complex
Rooney, N. & Streuli, C. H., 6 Jun 2011, In: FEBS Letters. 585, 11, p. 1663-1672 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile168 Downloads (Pure) -
The C terminus of talin links integrins to cell cycle progression
Wang, P., Ballestrem, C. & Streuli, C. H., 31 Oct 2011, In: Journal of Cell Biology. 195, 3, p. 499-513 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile175 Downloads (Pure) -
2010
Analysis of inhibitor of apoptosis protein family expression during mammary gland development
Owens, T. W., Foster, F. M., Tanianis-Hughes, J., Cheung, J. Y., Brackenbury, L. & Streuli, C. H., 2010, In: BMC Developmental Biology. 10, 71.Research output: Contribution to journal › Article › peer-review
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Cell-matrix interactions in mammary gland development and breast cancer.
Muschler, J. & Streuli, C. H., 1 Oct 2010, In: Cold Spring Harbor Perspectives in Biology. 2, 10, p. a003202Research output: Contribution to journal › Article › peer-review
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Role for X-linked inhibitor of apoptosis protein upstream of mitochondrial permeabilization
Owens, T. W., Foster, F. M., Valentijn, A., Gilmore, A. P. & Streuli, C. H., 2010, In: Journal of Biological Chemistry. 285, 2, p. 1081-1088 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile85 Downloads (Pure) -
2009
Advanced glycation end products in extracellular matrix proteins contribute to the failure of sensory nerve regeneration in diabetes
Duran-Jimenez, B., Dobler, D., Moffatt, S., Rabbani, N., Streuli, C. H., Thornalley, P. J., Tomlinson, D. R. & Gardiner, N. J., Dec 2009, In: Diabetes. 58, 12, p. 2893-2903 10 p.Research output: Contribution to journal › Article › peer-review
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Analyzing how cell adhesion controls mammary gland function by transplantation of embryonic mammary tissue from knockout mice.
Klinowska, T. C. M. & Streuli, C. H., 2009, In: Methods in Molecular Biology. 522, p. 331-345 14 p.Research output: Contribution to journal › Article › peer-review
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Extracellular matrix controls insulin signaling in mammary epithelial cells through the RhoA/Rok pathway
Lee, Y. J., Hsu, T. C., Du, J. Y., Valentijn, A. J., Wu, T. Y., Cheng, C. F., Yang, Z. & Streuli, C. H., Aug 2009, In: Journal of Cellular Physiology. 220, 2, p. 476-484 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile73 Downloads (Pure) -
FAK engages multiple pathways to maintain survival of fibroblasts and epithelia - Differential roles for paxillin and p130Cas
Zouq, N. K., Keeble, J. A., Lindsay, J., Valentijn, A. J., Zhang, L., Mills, D., Turner, C. E., Streuli, C. H. & Gilmore, A. P., 1 Feb 2009, In: Journal of Cell Science. 122, 3, p. 357-367 10 p.Research output: Contribution to journal › Article › peer-review
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Integrins and cell-fate determination
Streuli, C. H., 15 Jan 2009, In: Journal of Cell Science. 122, 2, p. 171-177 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile139 Downloads (Pure) -
Molecular dissection of integrin signalling proteins in the control of mammary epithelial development and differentiation
Akhtar, N., Marlow, R., Lambert, E., Schatzmann, F., Lowe, E. T., Cheung, J., Katz, E., Li, W., Wu, C., Dedhar, S., Naylor, M. J. & Streuli, C. H., 15 Mar 2009, In: Development. 136, 6, p. 1019-1027 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile125 Downloads (Pure) -
Signal co-operation between integrins and other receptor systems
Streulli, C. H. & Akhtar, N., 15 Mar 2009, In: Biochemical Journal. 418, 3, p. 491-506 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile279 Downloads (Pure) -
Targeting inhibitor of apoptosis proteins in combination with ErbB antagonists in breast cancer
Foster, F. M., Owens, T. W., Tanianis-Hughes, J., Clarke, R. B., Brennan, K., Bundred, N. J. & Streuli, C. H., 29 Jun 2009, In: Breast Cancer Research. 11, 3, R41.Research output: Contribution to journal › Article › peer-review