Accepting PhD Students

PhD projects

Immune response to nanomaterials

If you made any changes in Pure these will be visible here soon.

Personal profile



We work at the interface of material sciences, biology, and physiopathology, using the most advanced methodologies in each area to reveal which physicochemical or biological features of nanomaterials are the most likely to induce inflammation, genotoxicity or toxic reactions, with the ultimate aim to guide the production of safer nanomaterials using a safer-by-design approach.

Using carbon nanomaterials, in particular graphene based and two-dimensional materials, as case study, we have shown that dimensions, surface properties such as surface chemistry, and the ability of nanomaterials to adsorb biological molecules (bio-corona) are three essential parameters that can be used to predict the toxicity or inertness of manufactured nanomaterials.

Our team is currently contributing to one EU project funded under the H2020 programme, 

  • PLASTICHEAL , in which we aim to understand better the fate and effects of micro and nanoplastics after inhalation and ingestion


  • Faculty of Biology Medicine and Health: MBChB, MPharm, UG biological sciences, and PGT programmes
  • Faculty of Sciences and Engineering: CDT Graphene programme 

University of Manchester Roles



Employment history

  • 2022 - present | Senior Lecturer at the University of Manchester, Faculty of Biology, Medicine and Health, School of Biological Sciences
  • 2013-2022 | Lecturer at the University of Manchester
  • 2011 - 2013 | Marie Sklodowska-Curie career development Fellowship (EU-FP7, NanoNeuroHOP project) at UCL School of Pharmacy, University College London, UK. Project aiming to reveal the neuro safety profile of different carbon based materials, modified for biomedical applications.

  • 2010 - 2011 | Visiting Postdoctoral Research Associate at the Nanomedicine Lab, UCL School of Pharmacy, University College London, UK. Project aiming to assess the neuro safety profile of carbon nanotubes functionalised for biomedical applications. Project co-funded by French Government (Grenelle de l'Environment).
  • 2002 - 2005 | PhD research candidate/engineer at IRSN (Radiotoxicology and Radiobiology Lab) and IRBA (Institut de Recherche Biomédicale des Armées, former CRSSA, part of the French Defence Health Service), France. Project aiming to assess the neurotoxicity of radionucleides at environmental doses (project ENVIRHOM). This research was co-funded by the French Union Chamber of Mineral Waters (including Danone Group, Nestle Waters France, Neptune).



Research interests

Methodological knowledge

  • mammalian cell cultures
  • primary cell cultures: lung and peritoneal macrophages, brain cells
  • organotypic cell cultures
  • in vivo studies
  • cryo-/micro-/ultramicro-tomy
  • histology
  • immunohisto-/cyto-chemistry
  • cytotoxicity assays
  • RT-PCR
  • fluorescence imaging (epifluorescence, confocal)
  • electronic imaging (TEM, HR-TEM, S-TEM (EELS), SEM, env-SEM, cryo-TEM, cryo-SEM, FIB-SEM) and biological sample preparation