David Wedge, BA, PGCE, MSc, PhD

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  An evolutionary study of head and neck cancer before during and following radiotherapy - DEC 23

  Wedge, D. (PI) & Bristow, R. (CoI)

  1/09/24 → 31/08/25

  Project: Research

• DONATION: HereDitary homologous recOmbination repair deficiency (hHRD): defining and modeling the evolutioNary ecosystem to identify novel candidates for cancer eArly deTection and InterceptiOn, the paNreatic ductal adenocarcinoma (PDAC) paradigm.

  Woodward, E. (PI), Jorgensen, C. (CoI), Weaver, J. (CoI) & Wedge, D. (CoI)

  1/06/24 → 31/05/27

  Project: Research

• Oxford Nanopore PromethION

  Ellingford, J. (PI), Adamson, A. (CoI), Banka, S. (CoI), Black, G. (CoI), Brockhurst, M. (CoI), Coyte, K. (CoI), Gifford, D. (CoI), Hayes, A. (CoI), Hubbard, S. (CoI), Lagator, M. (CoI), Mcdermott, J. (CoI), Newman, W. (CoI), Sergouniotis, P. (CoI), Sharrocks, A. (CoI) & Wedge, D. (CoI)

  31/07/23 → 30/07/26

  Project: Research

• NIHR Manchester Biomedical Research Centre

  Bruce, I. (PI), Lord, G. (CoI), Lennon, R. (CoI), Black, G. (CoI), Wedge, D. (CoI), Morris, A. (CoI), Hussell, T. (CoI), Sharrocks, A. (CoI), Stivaros, S. (CoI), Buch, M. (CoI), Gough, J. (CoI), Kostarelos, K. (CoI), Thistlethwaite, F. (CoI), Kadler, K. (CoI), Barton, A. (CoI), Hyrich, K. (CoI), Mcbeth, J. (CoI), O'Neill, T. (CoI), Vestbo, J. (CoI), Simpson, A. (CoI), Singh, S. (CoI), Smith, J. (CoI), Felton, T. (CoI), Murray, C. (CoI), Griffiths, C. (CoI), Cullum, N. (CoI), Rhodes, L. (CoI), Warren, R. (CoI), Paus, R. (CoI), Dumville, J. (CoI), Viros Usandizaga, A. (CoI), Keavney, B. (CoI), Tomaszewski, M. (CoI), Allan, S. (CoI), Body, R. (CoI), Cartwright, E. (CoI), Heagerty, A. (CoI), Kalra, P. (CoI), Miller, C. (CoI), Rutter, M. (CoI), Smith, C. (CoI), Trafford, A. (CoI), Evans, D. (CoI), Crosbie, E. (CoI), Crosbie, P. (CoI), Harvie, M. (CoI), Howell, S. (CoI), Renehan, A. (CoI), Dive, C. (CoI), Blackhall, F. (CoI), Landers, D. (CoI), Krebs, M. (CoI), Cook, N. (CoI), Clarke, R. (CoI), Taylor, S. (CoI), Jorgensen, C. (CoI), Lorigan, P. (CoI), Jayson, G. (CoI), Valle, J. (CoI), Mccabe, M. (CoI), Armstrong, A. (CoI), Freitas, A. (CoI), Illidge, T. (CoI), Choudhury, A. (CoI), Hoskin, P. (CoI), West, C. (CoI), Van Herk, M. (CoI), Faivre-Finn, C. (CoI), Bristow, R. (CoI), Kirkby, K. (CoI), Birtle, A. (CoI), Mackay, R. (CoI), Radford, J. (CoI), Linton, K. (CoI), Higham, C. (CoI), Munro, K. (CoI), Plack, C. (CoI), Arden Armitage, C. (CoI), Bruce, I. (CoI), Moore, D. (CoI), Saunders, G. (CoI), Stone, M. (CoI), Haddock, G. (CoI), Lewis, S. (CoI), Elliott, R. (CoI), Green, J. (CoI), Lovell, K. (CoI), Morrison, A. (CoI), Shaw, J. (CoI), Bucci, S. (CoI), Ainsworth, J. (CoI), Webb, R. (CoI), Newman, W. (CoI), Banka, S. (CoI), Clayton-Smith, J. (CoI), Payne, K. (CoI), Moldovan, R. (CoI), Wynn, R. (CoI) & Jones, S. (CoI)

  1/12/22 → 30/11/27

  Project: Research

  • Biomedical Research 100%
  • Hearing Impairment 83%
  • Radiation Therapy 78%
  • Health Care Personnel 74%
  • Adverse Event 71%

• Data-driven cancer genome interpretation for personalised cancer treatment (PROJECT)

  Lindsay, C. (PI), Blackhall, F. (CoI) & Wedge, D. (CoI)

  1/11/22 → 31/10/27

  Project: Research

  • Data-driven 100%
  • Malignant Neoplasm 50%

• Measuring tumour radioresistance to improve radiotherapy outcomes (PROJECT)

  Choudhury, A. (PI), Bristow, R. (CoI), Forker, L. (CoI), Hoskin, P. (CoI), Nagarajan, S. (CoI), Wedge, D. (CoI) & West, C. (CoI)

  1/10/22 → 30/09/25

  Project: Research

  • Radiosensitivity 100%
  • Neoplasm 100%
  • Teaching Hospital 33%

• Improving patient outcomes in oesophageal adenocarcinoma using cancer evolutionary trajectories

  Wedge, D. (PI)

  1/02/22 → 31/01/25

  Project: Research

  • Early Cancer 100%
  • Esophageal Adenocarcinoma 100%