Research output per year
Research output per year
Personal profile
Overview
- Research Lead for Prevention of Co-Morbidity - NIHR Manchester Musculoskeletal Biomedical Research Unit
- Programme lead for the Norfolk Arthritis Register - Arthritis Research UK Centre for Epidemiology
- Professor of Rheumatology and Musculoskeletal Epidemiology
Biography
I completed my undergraduate medical training at the University of Birmingham Medical School. My pre-registration and general medical training were undertaken in the teaching hospitals of Birmingham. I trained in rheumatology at the Hammersmith Hospital, London; Guys Hospital, London and the teaching hospitals of Birmingham. My name was placed on the specialist register for rheumatology in 1986. I trained in Epidemiology at the University of Birmingham and at Erasmus University, Rotterdam, the Netherlands. I joined the Arthritis Research UK Epidemiology Unit in 1989. I was promoted to the Chair of Rheumatology and Musculoskeletal Epidemiology in 2001.
Research interests
My main research interest is in the epidemiology of inflammatory musculoskeletal conditions – in particular, risk factors for the development and outcome of rheumatoid arthritis. I am a Principal Investigator for the Norfolk Arthritis Register and the BSR Biologics Register. I have a major interest in drug safety and pharmacoepidemiology. I was the Director of the NIHR Manchester Musculoskeletal BRU until April 2014, and remain the Lead for the Prevention of Co-Morbidity Research theme. I was the Director of the Arthritis Research UK Centre for Epidemiology until August 2014 and remain involved in the Norfolk Arthritis Register and BSR Biologics Register-RA programmes.
My collaborations
- Professor George Kitas – Dudley Group of Hospitals NHS Trust
- Professor Jill Belch – University of Dundee
- Professor Alex MacGregor – University of East Anglia
Memberships of committees and professional bodies
- American College of Rheumatology
- Association of Physicians of Great Britain and Northern Ireland
- British Society of Paediatric and Adolescent Rheumatology
- British Society for Rheumatology (Distinguished member)
- Royal College of Physicians of London
- EULAR Honorary Member
Qualifications
- MB ChB (Birm) 1977
- MD (Birm) 1987
- FRCP 1994
- FFPH 2006
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Beacons, Institutes and Platforms
- Manchester Institute for Collaborative Research on Ageing
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Identifying and managing psoriasis-associated comorbidities: the IMPACT research programme
Cordingley, L., Nelson, P. A., Davies, L., Ashcroft, D., Bundy, C., Chew-Graham, C., Chisholm, A., Elvidge, J., Hamilton, M., Hilton, R., Kane, K., Keyworth, C., Littlewood, A., Lovell, K., Lunt, M., McAteer, H., Ntais, D., Parisi, R., Pearce, C. & Rutter, M. & 3 others, , Mar 2022, In: Programme Grants for Applied Research. 10, 3, p. 1-240 240 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A Multicenter, Randomized, Placebo‐Controlled Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients With Rheumatoid Arthritis
Kitas, G., Nightingale, P., Armitage, J., Sattar, N., Belch, J. F. & Symmons, D., 2019, In: Arthritis and Rheumatology.Research output: Contribution to journal › Article › peer-review
Open Access -
Cervical screening uptake and rates of cervical dysplasia in the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis
BSRBR-RA Control Centre Consortium, 5 Aug 2019, In: Rheumatology (Oxford).Research output: Contribution to journal › Article › peer-review
Open Access -
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data
International Inflammatory Bowel Disease Genetics Consortium (IIBDGC), 1 Dec 2019, In: Scientific Reports. 9, 1, 10351.Research output: Contribution to journal › Article › peer-review
Open Access -
Malignancy and mortality rates in patients with severe psoriatic arthritis requiring tumour-necrosis factor alpha inhibition: results from the British Society for Rheumatology Biologics Register
Fagerli, K. M., Kearsley-Fleet, L., Mercer, L. K., Watson, K., Packham, J., Symmons, D. P. M., Hyrich, K. L. & British Society for Rheumatology Biologics Register, 1 Jan 2019, In: Rheumatology (Oxford, England). 58, 1, p. 80-85Research output: Contribution to journal › Article › peer-review
Open Access
Projects
- 1 Finished
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Arthritis Research UK Centre of Excellence in Epidemiology.
Symmons, D. (PI), Bruce, I. (CoI), Dixon, W. (CoI), Felson, D. (CoI), Hyrich, K. (CoI), Lunt, M. (CoI), Mcbeth, J. (CoI), O'Neill, T. (CoI) & Verstappen, S. (CoI)
1/08/13 → 31/07/18
Project: Research
Impacts
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Biologics registers for immune-mediated inflammatory diseases: enhancing access to novel therapies and balancing drug safety concerns versus effectiveness
Hyrich, K. (Participant), Bruce, I. (Participant), Griffiths, C. (Participant), Warren, R. (Participant), Symmons, D. (Participant), Ashcroft, D. (Participant), Dixon, W. (Participant), Lunt, M. (Participant), Yiu, Z. (Participant) & Mercer, L. (Participant)
Impact: Health and wellbeing
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Improving treatment outcomes for patients with rheumatoid arthritis
Symmons, D. (Participant), Silman, A. (Participant), Hyrich, K. (Participant), Lunt, M. (Participant), Dixon, W. (Participant) & Verstappen, S. (Participant)
Impact: Health impacts, Societal impacts, Economic impacts
Datasets
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Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter cohort study
van Wesemael, T. J. (Contributor), Ajeganova, S. (Contributor), Humphreys, J. (Contributor), Terao, C. (Contributor), Muhammad, A. (Contributor), Symmons, D. (Contributor), MacGregor, A. J. (Contributor), Hafström, I. (Contributor), Trouw, L. A. (Contributor), van der Helm-van Mil, A. H. M. (Contributor), Huizinga, T. W. J. (Contributor), Mimori, T. (Contributor), Toes, R. E. M. (Contributor), Matsuda, F. (Contributor), Svensson, B. (Contributor), Verstappen, S. (Contributor) & Van Der Woude, D. (Contributor), figshare , 1 Dec 2016
DOI: 10.6084/m9.figshare.c.3640754.v1, https://figshare.com/collections/Smoking_is_associated_with_the_concurrent_presence_of_multiple_autoantibodies_in_rheumatoid_arthritis_rather_than_with_anti-citrullinated_protein_antibodies_per_se_a_multicenter_cohort_study/3640754/1
Dataset
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Prediction of primary non-response to methotrexate therapy using demographic, clinical and psychosocial variables: results from the UK Rheumatoid Arthritis Medication Study (RAMS)
Sergeant, J. (Contributor), Hyrich, K. (Contributor), Anderson, J. (Contributor), Kopec-Harding, K. (Contributor), Hope, H. (Contributor), Symmons, D. (Contributor), Barton, A. (Contributor) & Verstappen, S. (Contributor), figshare , 13 Jul 2018
DOI: 10.6084/m9.figshare.c.4165406.v1, https://figshare.com/collections/Prediction_of_primary_non-response_to_methotrexate_therapy_using_demographic_clinical_and_psychosocial_variables_results_from_the_UK_Rheumatoid_Arthritis_Medication_Study_RAMS_/4165406/1
Dataset