Research output per year
Research output per year
Search results
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2023
T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavity
Finlay, C. M., Parkinson, J. E., Zhang, L., Chan, B. H. K., Ajendra, J., Chenery, A., Morrison, A., Kaymak, I., Houlder, E. L., Murtuza Baker, S., Dickie, B. R., Boon, L., Konkel, J. E., Hepworth, M. R., MacDonald, A. S., Randolph, G. J., Rückerl, D. & Allen, J. E., 15 Mar 2023, In: Immunity.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
CD11c identifies microbiota and EGR2-dependent MHCII+ serous cavity macrophages with sexually dimorphic fate in mice
Bain, C. C., Louwe, P. A., Steers, N. J., Bravo-Blas, A., Hegarty, L. M., Pridans, C., Milling, S. W. F., MacDonald, A. S., Rückerl, D. & Jenkins, S. J., 24 May 2022, In: European journal of immunology.Research output: Contribution to journal › Article › peer-review
Open Access -
High-Dose Mycobacterium tuberculosis H37rv Infection in IL-17A- and IL-17A/F-Deficient Mice
Ritter, K., Behrends, J., Ruckerl, D., Hölscher, A., Volz, J., Prinz, I. & Hölscher, C., 14 Sept 2022, In: Cells. 11, 18, 2875.Research output: Contribution to journal › Article › peer-review
Open Access -
Monocyte-derived peritoneal macrophages protect C57BL/6 mice against surgery-induced adhesions
Sahputra, R., Dejyong, K., Woolf, A. S., Mack, M., Allen, J., Rückerl, D. & Herrick, S., 13 Sept 2022, (Accepted/In press) In: Frontiers in Immunology.Research output: Contribution to journal › Article › peer-review
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Post-transcriptional regulatory feedback encodes JAK-STAT signal memory of interferon stimulation
Kalliara, E., Kardyńska, M., Bagnall, J., Spiller, D. G., Muller, W., Ruckerl, D., Biswas, S. K., Śmieja, J. & Paszek, P., 27 Sept 2022, In: Frontiers in Immunology. 13, 947213, 947213.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Genotype and Th2 cells control monocyte to tissue resident macrophage differentiation during nematode infection of the pleural cavity
Finlay, C. M., Parkinson, J. E., Chan, B. H., Ajendra, J., Chenery, A., Morrison, A., Houlder, E. L., Baker, S. M., Dickie, B., Boon, L., MacDonald, A. S., Konkel, J. E., Rückerl, D. & Allen, J. E., 19 Dec 2021, In: bioRxiv.Research output: Contribution to journal › Article
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Ongoing Exposure to Peritoneal Dialysis Fluid Alters Resident Peritoneal Macrophage Phenotype and Activation Propensity.
Sutherland, T., Shaw, T., Lennon, R., Herrick, S. & Rückerl, D., 27 Jul 2021, In: Frontiers in Immunology. 12, 715209.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The magnitude of airway remodeling is not altered by distinct allergic inflammatory responses in BALB/c versus C57BL/6 mice but matrix composition differs
Parkinson, J., Pearson, S., Rückerl, D., Allen, J. & Sutherland, T., 1 Jul 2021, In: Immunology and cell biology. 99, 6, p. 640-655 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Activation of the NLRP3 inflammasome by particles from the Echinococcus granulosus laminated layer
Casaravilla, C., Pittini, Á., Rückerl, D., Allen, J. & Díaz, Á., Sept 2020, In: Infection and immunity. 88, 9, e00190-20.Research output: Contribution to journal › Article › peer-review
Open Access -
Eosinophil Deficiency Promotes Aberrant Repair and Adverse Remodeling Following Acute Myocardial Infarction
Toor, I. S., Rückerl, D., Mair, I., Ainsworth, R., Meloni, M., Spiroski, A.-M., Benezech, C., Felton, J. M., Thomson, A., Caporali, A., Keeble, T., Tang, K. H., Rossi, A. G., Newby, D. E., Allen, J. E. & Gray, G. A., 8 Jul 2020, In: JACC: Basic to Translational Science. 5, 7, p. 665-681 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Macrophages and parasites: mortal enemies or partners in crime?
Rückerl, D., 29 Apr 2020, (E-pub ahead of print) In: Parasite Immunology.Research output: Contribution to journal › Article › peer-review
Open Access -
The essential role played by B cells in supporting protective immunity against Trichuris muris infection is by controlling the Th1/Th2 balance in the mesenteric lymph nodes and depends on host genetic background
Sahputra, R., Rückerl, D., Couper, K., Muller, W. & Else, K., 2020, In: Frontiers in Immunology. 10, p. 1-14 14 p., 2842.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Enhanced monocyte recruitment and delayed alternative macrophage polarisation accompanies impaired repair following myocardial infarction in C57BL/6 compared to BALB/c mice
Toor, I. S., Rückerl, D., Mair, I., Thomson, A., Rossi, A. G., Newby, D. E., Allen, J. E. & Gray, G. A., 2019, In: Clinical and experimental immunology.Research output: Contribution to journal › Article › peer-review
Open Access -
Macrophages Assemble! But do they need IL-4R during Schistosomiasis?
Rückerl, D. & Cook, P., 3 Jul 2019, In: European journal of immunology.Research output: Contribution to journal › Article › peer-review
Open Access -
Particles from the Echinococcus granulosus laminated layer inhibit CD40 upregulation in dendritic cells by interfering with Akt activation
Pittini, Á., Martínez-acosta, Y. E., Casaravilla, C., Seoane, P. I., Rückerl, D., Quijano, C., Allen, J. E. & Díaz, A., 2019, In: Infection and immunity.Research output: Contribution to journal › Article › peer-review
Open Access -
2018
Myeloid cell recruitment versus local proliferation differentiates susceptibility from resistance to filarial infection
Campbell, S., Knipper, J., Ruckerl, D., Finlay, C., Logan, N., Minutti, C. M., Mack, M., Jenkins, S., Taylor, M. & Allen, J., 4 Jan 2018, In: eLife. 7, e30947, 30947.Research output: Contribution to journal › Article › peer-review
Open Access -
Purine metabolism controls innate lymphoid cell function and protects against intestinal injury
Crittenden, S., Cheyne, A., Adams, A., Forster, T., Robb, C. T., Felton, J., Ho, G.-T., Ruckerl, D., Rossi, A. G., Anderton, S. M., Ghazal, P., Satsangi, J., Howie, S. E. & Yao, C., 2018, In: Immunology and cell biology.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The transcription factor STAT6 mediates direct repression of inflammatory enhancers and limits activation of alternatively polarized macrophages
Czimmerer, Z., Daniel, B., Horvath, A., Ruckerl, D., Nagy, G., Kiss, M., Peloquin, M., Budai, M. M., Cuaranta-Monroy, I., Steiner, L., Nagy Jr, B., Poliska, S., Banko, C., Bacso, Z., Schulman, I. G., Sauer, S., Deleuze, J. F., Allen, J., Benko, S. & Nagy, L., 16 Jan 2018, In: Immunity. 48, 1, p. 0Research output: Contribution to journal › Article › peer-review
Open Access -
Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection
Sutherland, T. E., Rückerl, D., Logan, N., Duncan, S., Wynn, T. A. & Allen, J. E., 30 Nov 2018, In: PLoS Pathogens. 14, 11, e1007423.Research output: Contribution to journal › Article › peer-review
Open Access -
2017
Interleukin 4 promotes the development of ex-Foxp3 Th2 cells during immunity to intestinal helminths
Pelly, V. S., Coomes, S. M., Kannan, Y., Gialitakis, M., Entwistle, L. J., Perez-Lloret, J., Czieso, S., Okoye, I. S., Ruckerl, D., Allen, J., Brombacher, F. & Wilson, M. S., 15 May 2017, In: Journal of Experimental Medicine. 214, 6, p. 1809-1826 18 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Macrophage Origin Limits Functional Plasticity in Helminth-Bacterial Co-infection
Ruckerl, D., Campbell, S. M., Duncan, S., Sutherland, T., Jenkins, S. J., Hewitson, J. P., Barr, T. A., Jackson-Jones, L. H., Maizels, R. M. & Allen, J., 23 Mar 2017, In: PL o S Pathogens. 13, 3, e1006233.Research output: Contribution to journal › Article › peer-review
Open Access -
Suppressor of cytokine signaling 3 in macrophages prevents exacerbated Interleukin-6-Dependent Arginase-1 activity and early permissiveness to experimental tuberculosis
Schmok, E., Dar, M. A., Behrends, J., Erdmann, H., Rückerl, D., Endermann, T., Heitmann, L., Hessmann, M., Yoshimura, A., Rose-John, S., Scheller, J., Schaible, U. E., Ehlers, S., Lang, R. & Hölscher, C., 2017, In: Frontiers in Immunology. 8, NOV, 1537.Research output: Contribution to journal › Article › peer-review
Open Access -
2016
IL-33 delivery induces serous cavity macrophage proliferation independent of interleukin-4 receptor alpha
Jackson-Jones, L. H., Rückerl, D., Svedberg, F., Duncan, S., Maizels, R. M., Sutherland, T. E., Jenkins, S. J., McSorley, H. J., Bénézech, C., MacDonald, A. S. & Allen, J. E., Oct 2016, In: European journal of immunology. 46, 10, p. 2311–2321Research output: Contribution to journal › Article › peer-review
Open Access -
IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection.
Pelly, V. S., Kannan, Y., Coomes, S. M., Entwistle, L. J., Ruckerl, D., Seddon, B., Macdonald, A., MacDonald, A. S., McKenzie, A. & Wilson, M. S., 17 Feb 2016, In: Mucosal Immunology. 9, p. 1407–1417Research output: Contribution to journal › Article › peer-review
Open Access -
Particles from the Echinococcus granulosus laminated layer inhibit IL-4 and growth factor-driven Akt phosphorylation and proliferative responses in macrophages
Seoane, P. I., Ruckerl, D., Casaravilla, C., Barrios, A., Pittini, Á., MacDonald, A., Allen, J. & Díaz, Á., 2016, In: Scientific Reports. 6, 39204.Research output: Contribution to journal › Article › peer-review
Open Access -
The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p
Czimmerer, Z., Varga, T., Kiss, M., Vázquez, C. O., Doan-Xuan, Q. M., Ruckerl, D., Tattikota, S. G., Yan, X., Nagy, Z. S., Daniel, B., Poliska, S., Horvath, A., Nagy, G., Varallyay, E., Poy, M. N., Allen, J., Bacso, Z., Abreu-Goodger, C. & Nagy, L., 31 May 2016, In: Genome Medicine. 8, 63.Research output: Contribution to journal › Article › peer-review
Open Access -
2015
IL-17 and neutrophils: unexpected players in the type 2 immune response.
Allen, J. E., Sutherland, T. & Ruckerl, D., Jun 2015, In: Current opinion in immunology. 34Research output: Contribution to journal › Article › peer-review
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Oncogenic properties of apoptotic tumor cells in aggressive B cell lymphoma.
Ford, C. A., Petrova, S., Pound, J. D., Voss, J. J. L. P., Melville, L., Paterson, M., Farnworth, S. L., Gallimore, A. M., Cuff, S., Wheadon, H., Dobbin, E., Ogden, C. A., Dumitriu, I. E., Dunbar, D. R., Murray, P. G., Ruckerl, D., Allen, J. E., Hume, D. A., van Rooijen, N. & Goodlad, J. R. & 2 others, , 2 Mar 2015, In: Current biology . 25, 5Research output: Contribution to journal › Article › peer-review
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The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an 'M2' phenotype in response to Th2 immunologic challenge.
Mylonas, K. J., Jenkins, S. J., Castellan, R. F. P., Ruckerl, D., McGregor, K., Phythian-Adams, A. T., Hewitson, J. P., Campbell, S. M., MacDonald, A. S., Allen, J. E. & Gray, G. A., Jul 2015, In: Immunobiology. 220, 7Research output: Contribution to journal › Article › peer-review
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2014
Alternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct.
Gundra, U. M., Girgis, N. M., Ruckerl, D., Jenkins, S., Ward, L. N., Kurtz, Z. D., Wiens, K. E., Tang, M. S., Basu-Roy, U., Mansukhani, A., Allen, J. E. & Loke, P., 15 May 2014, In: Blood. 123, 20, p. e110–e122Research output: Contribution to journal › Article › peer-review
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Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage.
Sutherland, T., Logan, N., Ruckerl, D., Humbles, A. A., Allan, S., Papayannopoulos, V., Stockinger, B., Maizels, R. M. & Allen, J., 19 Oct 2014, In: Nature Immunology. 15, 12, p. 1116-1125Research output: Contribution to journal › Article › peer-review
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Macrophage proliferation, provenance, and plasticity in macroparasite infection.
Ruckerl, D. & Allen, J. E., Nov 2014, In: Immunological reviews. 262, 1Research output: Contribution to journal › Article › peer-review
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The secreted triose phosphate isomerase of Brugia malayi is required to sustain microfilaria production in vivo.
Hewitson, J. P., Ruckerl, D., Harcus, Y., Murray, J., Webb, L. M., Babayan, S. A., Allen, J. E., Kurniawan, A. & Maizels, R. M., Feb 2014, In: PL o S Pathogens. 10, 2Research output: Contribution to journal › Article › peer-review
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Unconventional maturation of dendritic cells induced by particles from the laminated layer of larval Echinococcus granulosus
Casaravilla, C., Pittini, Á., Ruckerl, D., Seoane, P. I., Jenkins, S. J., MacDonald, A. S., Ferreira, A. M., Allen, J. E. & Díaz, Á., 2014, In: Infection and immunity. 82, 8, p. 3164-3176 12 p.Research output: Contribution to journal › Article › peer-review
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2013
IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1.
Jenkins, S. J., Ruckerl, D., Thomas, G. D., Hewitson, J. P., Duncan, S., Brombacher, F., Maizels, R. M., Hume, D. A. & Allen, J. E., 21 Oct 2013, In: The Journal of experimental medicine. 210, 11Research output: Contribution to journal › Article › peer-review
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2012
Induction of IL-4Rα-dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo.
Ruckerl, D., Jenkins, S. J., Laqtom, N. N., Gallagher, I. J., Sutherland, T., Duncan, S., Buck, A. H. & Allen, J., 13 Sept 2012, In: Blood. 120, 11Research output: Contribution to journal › Article › peer-review
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The biology of nematode- and IL4Rα-dependent murine macrophage polarization in vivo as defined by RNA-Seq and targeted lipidomics.
Thomas, G. D., Ruckerl, D., Maskrey, B. H., Whitfield, P. D., Blaxter, M. L. & Allen, J. E., 13 Dec 2012, In: Blood. 120, 25Research output: Contribution to journal › Article › peer-review
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2011
DAP10 contributes to CD8+ T cell-mediated cytotoxic effector mechanisms during Mycobacterium tuberculosis infection
Heßmann, M., Rausch, A., Rückerl, D., Adams, P. S., Simon, M., Gilfillan, S., Colonna, M., Ehlers, S. & Hölscher, C., May 2011, In: Immunobiology. 216, 5, p. 639-647 9 p.Research output: Contribution to journal › Article › peer-review
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Local macrophage proliferation, rather than recruitment from the blood, is a signature of T H2 inflammation
Jenkins, S. J., Ruckerl, D., Cook, P., Jones, L. H., Finkelman, F. D., Van Rooijen, N., MacDonald, A. S. & Allen, J. E., 10 Jun 2011, In: Science. 332, 6035, p. 1284-1288 4 p.Research output: Contribution to journal › Article › peer-review
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Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function.
Whyte, C. S., Bishop, E. T., Ruckerl, D., Gaspar-Pereira, S., Barker, R. N., Allen, J. E., Rees, A. J. & Wilson, H. M., Nov 2011, In: Journal of leukocyte biology. 90, 5Research output: Contribution to journal › Article › peer-review
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2007
Dendritic cell-derived IL-12p40 homodimer contributes to susceptibility in cutaneous leishmaniasis in BALB/c mice
Nigg, A. P., Zahn, S., Rückerl, D., Hölscher, C., Yoshimoto, T., Ehrchen, J. M., Wölbing, F., Udey, M. C. & Von Stebut, E., 1 Jun 2007, In: Journal of Immunology. 178, 11, p. 7251-7258 8 p.Research output: Contribution to journal › Article › peer-review
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Immunologie der tuberkulose - Grundlage neuer therapieansätze?
Translated title of the contribution :Immunology of tuberculosis - Basis for new therapeutic approach? Research output: Contribution to journal › Article › peer-review
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2006
Alternatively activated macrophages express the IL-27 receptor alpha chain WSX-1
Rückerl, D., Heßmann, M., Yoshimoto, T., Ehlers, S. & Hölscher, C., 14 Sept 2006, In: Immunobiology. 211, 6-8, p. 427-436 10 p.Research output: Contribution to journal › Article › peer-review
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Small organic compounds enhance antigen loading of class II major histocompatibility complex proteins by targeting the polymorphic P1 pocket
Höpner, S., Dickhaut, K., Hofstätter, M., Krämer, H., Rückerl, D., Söderhäll, J. A., Gupta, S., Marin-Esteban, V., Kühne, R., Freund, C., Jung, G., Falk, K. & Rötzschke, O., 15 Dec 2006, In: Journal of Biological Chemistry. 281, 50, p. 38535-38542 8 p.Research output: Contribution to journal › Article › peer-review
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2005
The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis
Hölscher, C., Hölscher, A., Rückerl, D., Yoshimoto, T., Yoshida, H., Mak, T., Saris, C. & Ehlers, S., 15 Mar 2005, In: Journal of Immunology. 174, 6, p. 3534-3544 11 p.Research output: Contribution to journal › Article › peer-review
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2004
Reduction of tamoxifen resistance in human breast carcinomas by tamoxifen-containing liposomes in vivo
Zeisig, R., Rückerl, D. & Fichtner, I., Aug 2004, In: Anticancer Drugs. 15, 7, p. 707-14 8 p.Research output: Contribution to journal › Article › peer-review