Elena Bichenkova

EmailElena.V.Bichenkovamanchester.acuk

Accepting PhD Students

PhD projects

Our research is focused on the development of “smart”, catalytic destroyers of harmful microRNAs that can find, capture and demolish microRNAs over-expressed in the disease states (i.e., cancer, neuroinflammation, Alzheimer’s disease). To engineer such catalytic agents, we chemically link together a short DNA fragment (to bind particular stretches of microRNA) with catalytic peptides (to destroy them by cleavage into small non-functional fragments).

8 results

2010

Novel Cryptolepine analogues: interactions with a 12-mer DNA oligonucleotide duplex.
Lavrado, J. P., 2010
Research output: Thesis › Doctoral Thesis
2009

"Chemical synthesis and investigation of physico-chemical properties of Artificial Ribonucleases."
Rattu, J., 2009
Research output: Thesis › Doctoral Thesis
Myo-Inositol based fluorescence quenched molecular probes and synthesis of autoinducer-2 (AI-2)
Kadirvel, M., 2009, Manchester. 196 p.
Research output: Thesis › Doctoral Thesis
2006

Locked nucleic acid analogues for novel exciplex-based molecular probes
Rogert Bacigalupo, M., 2006, Manchester: University of Manchester. 199 p.
Research output: Thesis › Doctoral Thesis
Novel fluorescent molecular probes for detection of nucleic acids.
Yu, X., 2006, (Unpublished)
Research output: Thesis › Doctoral Thesis
2004

"Molecular design and investigation of catalytic activity of high efficiency artificial ribonucleases."
Fabani, M., 2004
Research output: Thesis › Doctoral Thesis
2003
Studies of fluorescence detection of nucleic acid sequence
Savage, H., 2003, Manchester. 225 p.
Research output: Thesis › Doctoral Thesis
2002
Interaction of Human Thymidylate Synthase with its Own mRNA and Other Ligands
Hasnat, A., 2002, Manchester: University of Manchester. 237 p.
Research output: Thesis › Doctoral Thesis

Open Access

Elena Bichenkova, PhD, BSc

Supervised Work

Search results

2010

2009

2006

2004

2003

2002