Research output per year
Research output per year
Personal profile
Overview
Maternal health is critical both for reproductive success and for the long-term health of offspring. Exposure to an adverse intrauterine environment (due to factors such as maternal disease, poor nutrition or stress) is associated not only with increased risk of pregnancy complications, but also impairs fetal growth and development, predisposing these offspring to hypertension, diabetes, cancer and neurobehavioural disorders in adult life. Clearly, optimising maternal health before and during pregnancy could have significant benefits for population health.
My research interests focus on developing a mechanistic understanding of how environmental influences and maternal physiology impact both maternal and fetal health during pregnancy, and can programme disease risk in later life. A major goal is to identify therapies or interventions that will improve pregnancy outcomes and lifelong health.
Biography
Following an Honour's degree in Physiology from the University of Otago in New Zealand, Lizzy moved to the University of Cambridge in the UK to complete her PhD studies, graduating in 2009. After a post-doctoral position at the University of Edinburgh, Lizzy moved to the University of Manchester in 2011 and in 2015 was awarded a Fellowship from the British Heart Foundation to establish her independent research group within the maternal and fetal health research centre. In 2021, she was appointed as a Lecturer in maternal and fetal health.
Memberships of committees and professional bodies
Society for Endocrinology (UK)
The Physiological Society (UK)
The Endocrine Society (USA)
The British Society for Neuroendocrinology
Qualifications
BSc (Hons) Physiology, University of Otago, 2000-2004
PhD, University of Cambridge, 2005-2009
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Areas of expertise
- QP Physiology
- Reproductive biology
- Pregnancy
- Nutrition
- Developmental biology
- RM Therapeutics. Pharmacology
- Pregnancy therapeutics
Research Beacons, Institutes and Platforms
- Lydia Becker Institute
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Bumps and bacteria: influence of the maternal microbiota on pregnancy outcomes
Willmott, T. & Cottrell, E. C., 4 Mar 2024, In: Journal of Endocrinology. 261, 2, 230360.Research output: Contribution to journal › Review article › peer-review
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CHronic hypERtension and L-citRulline studY (CHERRY): an Early-Phase Randomised Controlled Trial in Pregnancy
Ormesher, L., Worton, S. A., Best, A., Dodd, S. R., Dempsey, A., Cottrell, E. C., Glossop, H., Chmiel, C., Wu, H. Y., Hardwick, B., Hennessy, S., Johnstone, E. D. & Myers, J. E., 1 Feb 2024, In: REPRODUCTIVE SCIENCES. 31, 2, p. 560-568 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Investigating the Association Between Nitrate Dosing and Nitrite Generation by the Human Oral Microbiota in Continuous Culture
Willmott, T., Serrage, H., Cottrell, E., Humphreys, G., Myers, J., Campbell, P. & Mcbain, A., 17 Apr 2024, In: Applied and environmental microbiology.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Downloads (Pure) -
Altered Oral Nitrate Reduction and Bacterial Profiles in Hypertensive Women Predict Blood Pressure Lowering Following Acute Dietary Nitrate Supplementation
Willmott, T., Ormesher, L., Mcbain, A. J., Humphreys, G. J., Myers, J. E., Singh, G., Lundberg, J. O., Weitzberg, E., Nihlen, C. & Cottrell, E. C., 13 Sept 2023, (E-pub ahead of print) In: Hypertension.Research output: Contribution to journal › Article › peer-review
Open AccessFile44 Downloads (Pure) -
Fetoplacental vascular effects of maternal adrenergic antihypertensive and cardioprotective medications in pregnancy
Tropea, T., Mavichak, W., Evangelinos, A., Brennan-Richardson, C., Cottrell, E., Myers, J., Johnstone, E. & Brownbill, P., 1 Nov 2023, In: J Hypertens. 41, 11, p. 1675-1687 13 p.Research output: Contribution to journal › Review article › peer-review
Open Access
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Maternal & Fetal Health Research Centre
Stevens, A. (PI), Heazell, A. (PI), Tower, C. (PI), Brison, D. (PI), Johnstone, E. (PI), Cottrell, E. (PI), Mann, E. (PI), Ingram, E. (PI), Crocker, I. (PI), Chernyavsky, I. (PI), Myers, J. (PI), Aplin, J. (PI), Higgins, L. (PI), Harris, L. (PI), Dilworth, M. (PI), Westwood, M. (PI), Whitworth, M. (PI), Desforges, M. (PI), Brownbill, P. (PI), Ruane, P. (PI), Sturmey, R. (PI), Worton, S. (PI), Greenwood, S. (PI) & Sibley, C. (PI)
1/09/18 → 31/12/35
Project: Research
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Can plant-derived extracellular vesicles improve outcomes in pregnancies complicated by maternal obesity?
Westwood, M. (PI), Cottrell, E. (CoI), Desforges, M. (CoI), Dilworth, M. (CoI), Mann, E. (CoI), Mcbain, A. (CoI) & Stevens, A. (CoI)
1/05/24 → 30/04/27
Project: Research
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Tommy's 2024-2025 Annual Budget
Heazell, A. (PI), Aplin, J. (CoI), Brownbill, P. (CoI), Cottrell, E. (CoI), Desforges, M. (CoI), Dilworth, M. (CoI), Higgins, L. (CoI), Johnstone, E. (CoI), Myers, J. (CoI), Palin, V. (CoI), Ruane, P. (CoI), Stevens, A. (CoI), Tropea, T. (CoI), Westwood, M. (CoI) & Worton, S. (CoI)
1/04/24 → 31/03/25
Project: Research
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Evaluation of the Safety of Maternal Anti-hypertensive Medicines on Placental Vascular Function.
Brownbill, P. (PI), Cottrell, E. (CoI), Johnstone, E. (CoI), Myers, J. (CoI) & Tropea, T. (Grant contributor)
1/11/19 → 31/10/22
Project: Research
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A Heme-Binding Agent for the Prevention of Fetal Vascular Compromise.
Dilworth, M. (PI), Brownbill, P. (CoI), Cottrell, E. (CoI), Johnstone, E. (CoI), Heazell, A. (CoI) & Crocker, I. (CoI)
1/11/18 → 30/11/23
Project: Research
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RCOG annual academic meeting
Cottrell, E. (Invited speaker)
18 Jan 2019Activity: Talk or presentation › Invited talk › Research
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Glasgow Pregnancy Research Symposium
Cottrell, E. (Invited speaker)
2 Feb 2018Activity: Talk or presentation › Invited talk › Research
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University College London (UCL)
Cottrell, E. (Secondee)
1 Nov 2016 → 30 Oct 2019Activity: External visiting positions or secondments › Visiting an external academic institution › Research
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The Physiological Society 2016
Cottrell, E. (Invited speaker)
29 Jul 2016 → 31 Jul 2016Activity: Talk or presentation › Invited talk › Research
Impacts
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Seeking a treatment to improve heart function and reduce future cardiovascular risk for women diagnosed with pre-eclampsia during their pregnancy (Enalapril)
Ormesher, L. (Corresponding participant), Johnstone, E. (Participant), Myers, J. (Participant), Cottrell, E. (Participant) & Trafford, A. (Participant)
Impact: Health and wellbeing