Research output per year
Research output per year
Personal profile
Overview
Maternal health is critical both for reproductive success and for the long-term health of offspring. Exposure to an adverse intrauterine environment (due to factors such as maternal disease, poor nutrition or stress) is associated not only with increased risk of pregnancy complications, but also impairs fetal growth and development, predisposing these offspring to hypertension, diabetes, cancer and neurobehavioural disorders in adult life. Clearly, optimising maternal health before and during pregnancy could have significant benefits for population health.
My research interests focus on developing a mechanistic understanding of how environmental influences and maternal physiology impact both maternal and fetal health during pregnancy, and can programme disease risk in later life. A major goal is to identify therapies or interventions that will improve pregnancy outcomes and lifelong health.
Biography
Following an Honour's degree in Physiology from the University of Otago in New Zealand, Lizzy moved to the University of Cambridge in the UK to complete her PhD studies, graduating in 2009. After a post-doctoral position at the University of Edinburgh, Lizzy moved to the University of Manchester in 2011 and in 2015 was awarded a Fellowship from the British Heart Foundation to establish her independent research group within the maternal and fetal health research centre. In 2021, she was appointed as a Lecturer in maternal and fetal health.
Memberships of committees and professional bodies
Society for Endocrinology (UK)
The Physiological Society (UK)
The Endocrine Society (USA)
The British Society for Neuroendocrinology
Qualifications
BSc (Hons) Physiology, University of Otago, 2000-2004
PhD, University of Cambridge, 2005-2009
Further information
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Areas of expertise
- QP Physiology
- Reproductive biology
- Pregnancy
- Nutrition
- Developmental biology
- RM Therapeutics. Pharmacology
- Pregnancy therapeutics
Research Beacons, Institutes and Platforms
- Lydia Becker Institute
Fingerprint
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Chronic developmental hypoxia alters mitochondrial oxidative capacity and reactive oxygen species production in the fetal rat heart in a sex‐dependent manner
Smith, K. L. M., Swiderska, A., Lock, M. C., Graham, L., Iswari, W., Choudhary, T., Thomas, D., Kowash, H. M., Desforges, M., Cottrell, E. C., Trafford, A. W., Giussani, D. A. & Galli, G. L. J., 8 Aug 2022, In: Journal of Pineal Research.Research output: Contribution to journal › Article › peer-review
Open Access -
Postnatal cardiovascular morbidity following preterm pre-eclampsia: an observational study
Ormesher, L., Higson, S., Luckie, M., Roberts, S. A., Glossop, H., Trafford, A., Cottrell, E., Johnstone, E. D. & Myers, J. E., 17 Aug 2022, In: Pregnancy Hypertension.Research output: Contribution to journal › Article › peer-review
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Enhanced nitrite-mediated relaxation of placental blood vessels exposed to hypoxia is preserved in pregnancies complicated by fetal growth restriction
Tropea, T., Nihlen, C., Weitzberg, E., Lundberg, J. O., Wareing, M., Greenwood, S., Sibley, C. & Cottrell, E., 26 Apr 2021, In: International Journal of Molecular Sciences.Research output: Contribution to journal › Article › peer-review
Open Access -
Antenatal sildenafil citrate treatment increases offspring blood pressure in the placental-specific Igf2 knockout mouse model of FGR
Renshall, L., Cottrell, E., Cowley, E., Sibley, C., Baker, P. N., Thortensen, E. B., Greenwood, S., Wareing, M. & Dilworth, M., 1 Feb 2020, In: American Journal of Physiology: Heart and Circulatory Physiology. 318, 2, p. H252-H263Research output: Contribution to journal › Article › peer-review
Open Access -
Beetroot juice lowers blood pressure and improves endothelial function in pregnant eNOS-/- mice: importance of nitrate-independent effects
Tropea, T., Renshall, L., Nihlen, C., Weitzberg, E., Lundberg, J. O., David, A. L., Tsatsaris, V., Stuckey, D. J., Wareing, M., Greenwood, S., Sibley, C. & Cottrell, E., 5 May 2020, In: The Journal of Physiology. 598, 18, p. 4079-4092Research output: Contribution to journal › Article › peer-review
Open Access
Projects
- 2 Finished
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Maternal & Fetal Health Research Centre
Stevens, A., Heazell, A., Tower, C., Brison, D., Johnstone, E., Cottrell, E., Mann, E., Ingram, E., Crocker, I., Chernyavsky, I., Myers, J., Aplin, J., Higgins, L., Harris, L., Dilworth, M., Westwood, M., Whitworth, M., Desforges, M., Brownbill, P., Ruane, P., Sturmey, R., Worton, S., Greenwood, S. & Sibley, C.
1/09/18 → 31/12/22
Project: Research
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Evaluation of the Safety of Maternal Anti-hypertensive Medicines on Placental Vascular Function.
Brownbill, P., Cottrell, E., Johnstone, E., Myers, J. & Tropea, T.
1/11/19 → 31/10/22
Project: Research
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RCOG annual academic meeting
Elizabeth Cottrell (Invited speaker)
18 Jan 2019Activity: Talk or presentation › Invited talk
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Glasgow Pregnancy Research Symposium
Elizabeth Cottrell (Invited speaker)
2 Feb 2018Activity: Talk or presentation › Invited talk
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University College London (UCL)
Elizabeth Cottrell (Secondee)
1 Nov 2016 → 30 Oct 2019Activity: External visiting positions or secondments › Visiting an external academic institution
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The Physiological Society 2016
Elizabeth Cottrell (Invited speaker)
29 Jul 2016 → 31 Jul 2016Activity: Talk or presentation › Invited talk
Impacts
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Seeking a treatment to improve heart function and reduce future cardiovascular risk for women diagnosed with pre-eclampsia during their pregnancy (Enalapril)
Laura Ormesher (Participant), Edward Johnstone (Participant), Jenny Myers (Participant), Elizabeth Cottrell (Participant) & Andrew Trafford (Participant)
Impact: Health and wellbeing