Elizabeth Cartwright

2024

Empowering artificial intelligence in characterizing the human primary pacemaker of the heart at single cell resolution

Chelu, A., Cartwright, E. J. & Dobrzynski, H., 18 Jun 2024, In: Scientific Reports.

Research output: Contribution to journal › Article › peer-review

Open Access

On the role of dysferlin in striated muscle: membrane repair, t-tubules and Ca2+ handling

Quinn, C. J., Cartwright, E. J., Trafford, A. W. & Dibb, K. M., 1 May 2024, In: The Journal of physiology. 602, 9, p. 1893-1910

Research output: Contribution to journal › Article › peer-review

Open Access

Treatment with αvβ3-integrin-specific 29P attenuates pressure-overload induced cardiac remodelling after transverse aortic constriction in mice

Njegić, A., Laid, L., Zi, M., Maniati, E., Wang, J., Chelu, A., Wisniewski, L., Hunter, J., Prehar, S., Stafford, N., Gilon, C., Hoffman, A., Weinmüller, M., Kessler, H., Cartwright, E. J. & Hodivala-Dilke, K., 1 Jun 2024, In: Journal of Molecular and Cellular Cardiology Plus. 8, 100069.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Extracellular Histone-Induced Protein Kinase C Alpha Activation and Troponin Phosphorylation Is a Potential Mechanism of Cardiac Contractility Depression in Sepsis

Abrams, S. T., Alhamdi, Y., Zi, M., Guo, F., Du, M., Wang, G., Cartwright, E. J. & Toh, C.-H., 6 Feb 2023, In: International Journal of Molecular Sciences. 24, 4, 3225.

Research output: Contribution to journal › Article › peer-review

Open Access

Restored autophagy is protective against PAK3-induced cardiac dysfunction

Ruiz Velasco Hernandez, A., Raja, R., Chen, X., Ganenthiran, H., Kaur, N., Alatawi, N. H. O., Miller, J. M., Abouleisa, R. R. E., Ou, Q., Zhao, X., Fonseka, O., Wang, X., Hille, S., Frey, N., Wang, T., Mohamed, T., Müller, O. J., Cartwright, E. & Liu, W., 16 Jun 2023, In: iScience. 26, 6, 106970.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Cardiomyocyte-specific loss of plasma membrane calcium ATPase 1 impacts cardiac rhythm and is associated with ventricular repolarisation dysfunction

Wilson, C., Stafford, N., Zi, M., Chelu, A., Niort, B. C., Li, Y., Baudoin, F., Prehar, S., Trafford, A. W. & Cartwright, E. J., 1 Aug 2022, In: Journal of molecular and cellular cardiology.

Research output: Contribution to journal › Article › peer-review

Open Access

File

23 Downloads (Pure)

Differential remodelling of mitochondrial subpopulations and mitochondrial dysfunction are a feature of early stage diabetes

Rajab, B., Kassab, S., Mironov, A., Stonall, C., Daghistani, H., Gibbons, S., Mamas, M., Smith, D., Albalawi, Z., Baudoin, F., Zi, M., Prehar, S., Cartwright, E., Zhang, Y. H. & Kitmitto, A., 19 Jan 2022, In: Scientific Reports. 12, 1, 978.

Research output: Contribution to journal › Article › peer-review

Open Access

Micro RNA-411 Expression Improves Cardiac Phenotype Following Myocardial Infarction in Mice

Nugroho, A. B., Stafford, N., Zi, M., Prehar, S., Potter, R., Kwon, D., Kohar, Y. S., Triastuti, E., Bui, T. A., Cartwright, E. J. & Oceandy, D., Sept 2022, In: JACC: Basic to Translational Science. 7, 9, p. 859-875 17 p.

Research output: Contribution to journal › Article › peer-review

Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy

Kaur, N., Ruiz-velasco, A., Raja, R., Howell, G., Miller, J. M., Abouleisa, R. R. E., Ou, Q., Mace, K., Hille, S. S., Frey, N., Binder, P., Smith, C. P., Fachim, H., Soran, H., Swanton, E., Mohamed, T. M. A., Müller, O. J., Wang, X., Chernoff, J. & Cartwright, E. J. & 1 others, Liu, W., 23 Feb 2022, In: iScience. 25, 3, p. 103973 103973.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate

D’Souza, A., Wang, Y., Anderson, C., Bucchi, A., Baruscotti, M., Olieslagers, S., Mesirca, P., Johnsen, A. B., Mastitskaya, S., Ni, H., Zhang, Y., Black, N., Cox, C., Wegner, S., Bano-Otalora, B., Petit, C., Gill, E., Logantha, S. J. R. J., Dobrzynski, H. & Ashton, N. & 10 others, Hart, G., Zhang, R., Zhang, H., Cartwright, E. J., Wisloff, U., Mangoni, M. E., Martins, P. A. D. C., Piggins, H. D., DiFrancesco, D. & Boyett, M. R., 1 May 2021, In: Heart Rhythm. 18, 5, p. 801-810 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Intrinsic Electrical Remodeling Underlies Atrioventricular Block in Athletes

Mesirca, P., Nakao, S., Nissen, S. D., Forte, G., Anderson, C., Trussell, T., Li, J., Cox, C., Zi, M., Logantha, S. J. R., Yaar, S., Carstensen, H., Bidaud, I., Stuart, L., Soattin, L., Morris, G. M., da Costa Martins, P. A., Cartwright, E. J., Oceandy, D. & Mangoni, M. E. & 5 others, Jespersen, T., Buhl, R., Dobrzynski, H., Boyett, M. R. & D'Souza, A., 14 Apr 2021, In: Circulation research.

Research output: Contribution to journal › Article › peer-review

Plasma membrane calcium ATPase 1 regulates human umbilical vein endothelial cell angiogenesis and viability

Njegic, A., Swiderska, A., Marris, C., Armesilla, A. L. & Cartwright, E. J., 26 Mar 2021, In: Journal of molecular and cellular cardiology. 156, p. 79-81

Research output: Contribution to journal › Letter › peer-review

Substrate for the Myocardial Inflammation-Heart Failure Hypothesis Identified Using Novel USPIO Methodology

Lagan, J., Naish, J., Simpson, K., Zi, M., Cartwright, E., Foden, P., Morris, J., Clark, D., Birchall, L., Caldwell, J., Trafford, A., Fortune, C., Cullen, M. H., Chaudhuri, N., Fildes, J., Sarma, J., Schelbert, E. B., Schmitt, M., Piper Hanley, K. & Miller, C., 1 Feb 2021, In: JACC: Cardiovascular Imaging. 14, 2, p. 365-376 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

Adenoviral Mediated Delivery of OSKM Factors Induces Partial Reprogramming of Mouse Cardiac Cells In Vivo

Kisby, T., Lázaro, I., Fisch, S., Cartwright, E. J., Cossu, G. & Kostarelos, K., 27 Oct 2020, (E-pub ahead of print) In: Advanced Therapeutics. p. 2000141

Research output: Contribution to journal › Article › peer-review

Open Access

Cardiac mitochondrial function depends on BUD23 mediated ribosome programming

Baxter, M., Voronkov, M., Poolman, T., Galli, G., Pinali, C., Goosey, L., Knight, A., Krakowiak, K., Maidstone, R., Iqbal, M., Zi, M., Prehar, S., Cartwright, E. J., Gibbs, J., Matthews, L. C., Adamson, A. D., Humphreys, N. E., Rebelo-guiomar, P., Minczuk, M. & Bechtold, D. A. & 2 others, Loudon, A. & Ray, D., 15 Jan 2020, In: eLife. 9, e50705.

Research output: Contribution to journal › Article › peer-review

Open Access

Investigating the role of KMT2C in heart development

Borland, S. C., Tenin, G., Monaghan, R., Williams, S., Zi, M., Wilson, C., Prehar, S., Cartwright, E., Abraham, S. & Keavney, B., Dec 2020, In: European Journal of Human Genetics. 28, SUPPL 1, p. 42-42 1 p.

Research output: Contribution to journal › Meeting Abstract › peer-review

Signaling via the Interleukin-10 Receptor Attenuates Cardiac Hypertrophy in Mice During Pressure Overload, but not Isoproterenol Infusion

Stafford, N., Assrafally, F., Prehar, S., Zi, M., De Morais, A. M., Maqsood, A., Cartwright, E., Mueller, W. & Oceandy, D., 30 Oct 2020, (E-pub ahead of print) In: Frontiers in Pharmacology.

Research output: Contribution to journal › Article › peer-review

Open Access

Silencing miR-370-3p rescues funny current and sinus node function in heart failure

Yanni Gerges, J., D'Souza, A., Wang, Y., Li, N., Hansen, B. J., Zakharkin, S., Smith, M., Hayward, C., Whitson, B. A., Mohler, P. J., Janssen, P. M. L., Zeef, L., Choudhury, M., Zi, M., Cai, X., Logantha, S., Nakao, S., Atkinson, A., Petkova, M. & Doris, U. & 8 others, Ariyaratnam, J., Cartwright, E., Griffiths-Jones, S., Hart, G., Federov, V. V., Oceandy, D., Dobrzynski, H. & Boyett, M., 9 Jul 2020, In: Scientific Reports. 10, 11279.

Research output: Contribution to journal › Article › peer-review

Open Access

Targeting Ca2+ handling proteins for the treatment of heart failure and arrhythmias

Cartwright, E., Wilson, C. & Njegic, A., 4 Sept 2020, In: Frontiers in Physiology. 11, 1068.

Research output: Contribution to journal › Review article › peer-review

Open Access

Targeting mir128-3p alleviates myocardial insulin resistance and prevents ischemia-induced heart failure: javascript:void(0);

Ruiz-velasco, A., Zi, M., Hille, S. S., Azam, T., Kaur, N., Jiang, J., Nguyen, B., Sekeres, K., Binder, P., Collins, L., Pu, F., Xiao, H., Guan, K., Frey, N., Cartwright, E. J., Müller, O. J., Wang, X. & Liu, W., 30 Mar 2020, (E-pub ahead of print) In: eLife. 9

Research output: Contribution to journal › Article › peer-review

Open Access

2019

Cardiac hypertrophy or failure? - A systematic evaluation of the transverse aortic constriction model in C57BL/6NTac and C57BL/6J substrains

Zi, M., Stafford, N., Prehar, S., Baudoin, F., Oceandy, D., Wang, X., Bui, T., Shaheen, M., Neyses, L. & Cartwright, E., 1 Dec 2019, In: Current Research in Physiology.

Research output: Contribution to journal › Article › peer-review

Open Access

Cardiomyocyte damage control in heart failure and the role of the sarcolemma

Kitmitto, A., Baudoin, F. & Cartwright, E. J., 13 Sept 2019, In: Journal of Muscle Research and Cell Motility .

Research output: Contribution to journal › Article › peer-review

Open Access

Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response

Binder, P., Wang, S., Radu, M., Zi, M., Collins, L., Khan, S., Li, Y., Sekeres, K., Humphreys, N. E., Swanton, E., Reid, A., Pu, F., Oceandy, D., Guan, K., Hille, S., Frey, N., Müller, O. J., Cartwright, E. J., Chernoff, J. & Liu, W. & 1 others, Wang, X., 8 Jan 2019, In: Circulation research. 124, 5, p. 696-711 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Pharmacological Inhibition of Hippo Pathway using XMU‐MP‐1 Protects The Heart Against Adverse Effects during Pressure Overload

Triastuti, E., Nugroho, A. B., Zi, M., Prehar, S., Kohar, Y. S., Bui, T. A., Stafford, N., Cartwright, E. J., Abraham, S. & Oceandy, D., 2019, In: British Journal of Pharmacology.

Research output: Contribution to journal › Article › peer-review

Open Access

2018

Obesity causes cardiac ion channel remodelling and increases the propensity for atrial arrhythmias

Webb, K., Logantha, S. J., Absi, M., Cartwright, E., Zhang, H., Monfredi, O. & Boyett, M. R., Aug 2018, In: European Heart Journal . 39, p. 1204-1204

Research output: Contribution to journal › Meeting Abstract › peer-review

2017

Acute inhibition of PMCA4, but not global ablation, reduces blood pressure and arterial contractility via a nNOS-dependent mechanism

Lewis, S., Little, R., Baudoin, F., Prehar, S., Neyses, L., Cartwright, E. & Austin, C., 2017, In: Journal of cellular and molecular medicine.

Research output: Contribution to journal › Article › peer-review

Open Access

Advanced glycation end products reduce the calcium transient in cardiomyocytes by increasing production of reactive oxygen species and nitric oxide

Hegab, Z., Mohamed, T. M. A., Stafford, N., Mamas, M., Cartwright, E. J. & Oceandy, D., Nov 2017, In: FEBS open bio. 7, 11, p. 1672-1685 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Genetic ablation of the mammalian sterile-20 like kinase 1 (Mst1) improves cell reprogramming efficiency and increases induced pluripotent stem cell proliferation and survival

Robertson, A., Mohamed, T., El Maadawi, Z., Stafford, N., Bui, T., Lim, D. S., Cartwright, E. & Oceandy, D., 1 Apr 2017, In: Stem Cell Research. 20, p. 42-49 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Metabolic stress-induced cardiomyopathy is caused by mitochondrial dysfunction due to attenuated Erk5 signalling

Liu, W., Ruiz Velasco Hernandez, A., Wang, S., Khan, S., Zi, M., Jungmann, A., Camacho-Munoz, M. D., Guo, J., Du, G., Xie, L., Oceandy, D., Nicolaou, A., Galli, G., Müller, O. J., Cartwright, E., Ji, Y. & Wang, X., 8 Sept 2017, In: Nature Communications. 8, 494.

Research output: Contribution to journal › Article › peer-review

Open Access

Obesity increases the propensity for atrial arrhythmias

Webb, K., Absi, M., Logantha, S., Zaborska, K., Gurney, A., Heagerty, A., Cartwright, E., Zhang, H., Monfredi, O. & Boyett, M., 29 Aug 2017, European Heart Journal. Vol. 38. p. 637-637 P3011. (European Heart Journal ).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Plasma membrane Ca2+ ATPase 1 is required for maintaining atrial Ca2+ homeostasis and electrophysiological stability in the mouse

Wang, Y., Wilson, C., Cartwright, E. & Lei, M., 2017, In: The Journal of Physiology.

Research output: Contribution to journal › Article › peer-review

Open Access

Reduced Expression of PMCA1 is Associated with Increased Blood Pressure with Age Which is Preceded by Remodeling of Resistance Arteries

Little, R., Zi, M., Hammad, S. K., Nguyen, L., Njegic, A., Kurusamy, S., Prehar, S., Armesilla, A. L., Neyses, L., Austin, C. & Cartwright, E., 2017, In: Aging cell. 16, 5

Research output: Contribution to journal › Article › peer-review

Open Access

Selective inhibition of plasma membrane calcium ATPase 4 improves angiogenesis and vascular reperfusion

Kurusamy, S., López-Maderuelo, D., Little, R., Cadagan, D., Savage, A. M., Ihugba, J. C., Baggott, R. R., Rowther, F. B., Martínez-Martínez, S., Arco, P. G. D., Murcott, C., Wang, W., Francisco Nistal, J., Oceandy, D., Neyses, L., Wilkinson, R. N., Cartwright, E. J., Redondo, J. M. & Armesilla, A. L., Aug 2017, In: Journal of molecular and cellular cardiology. 109, p. 38-47 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Stress-Activated Kinase MKK7 Governs Epigenetics of Cardiac Repolarization for Arrhythmia Prevention

Chowdhury, S. K., Liu, W., Zi, M., Li, Y., Wang, S., Tsui, H., Prehar, S., Castro, S., Zhang, H., Ji, Y., Zhang, X., Xiao, R., Zhang, R., Lei, M., Cyganek, L., Guan, K., Millar, C. B., Liao, X., Jain, M. K. & Boyett, M. R. & 3 others, Cartwright, E. J., Shiels, H. A. & Wang, X., 2017, In: Circulation. 135, 7, p. 683-699 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

157 Downloads (Pure)

Targeting miR-423-5p Reverses Exercise Training-Induced HCN4 Channel Remodeling and Sinus Bradycardia

D'Souza, A., Pearman, C. M., Wang, Y., Nakao, S., Logantha, S. J. R. J., Cox, C., Bennett, H., Zhang, Y., Johnsen, A. B., Linscheid, N., Poulsen, P. C., Elliott, J., Coulson, J., McPhee, J., Robertson, A., Da Costa Martins, P. A., Kitmitto, A., Wisløff, U., Cartwright, E. J. & Monfredi, O. & 5 others, Lundby, A., Dobrzynski, H., Oceandy, D., Morris, G. M. & Boyett, M. R., 13 Oct 2017, In: Circulation research. 121, 9, p. 1058-1068 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

The plasma membrane calcium ATPases and their role as major new players in human disease.

Stafford, N., Wilson, C., Oceandy, D., Neyses, L. & Cartwright, E. (Corresponding), 2017, In: Physiological Reviews. 97, 3, p. 1089-1125 37 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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301 Downloads (Pure)

2016

187 Mitochondrial Dysfunction in the Diabetic Heart â€” Imbalance in Fusion/Fission Axis?

Murfitt, L., Monib, M. M., Bennett, H., Davenport, B., Pinali, C., Cooper, G., Cartwright, E. & Kitmitto, A., Jun 2016, In: Heart. 102, 6, p. A128-A128

Research output: Contribution to journal › Meeting Abstract › peer-review

Atrioventricular node dysfunction and ion channel transcriptome in pulmonary hypertension

Temple, I., Logantha, S., Absi, M., Zhang, Y., Pervolaraki, E., Yanni Gerges, J., Atkinson, A., Petkova, M., Quigley, G., Castro, S., Drinkhill, M. J., Schneider, H., Monfredi, O., Cartwright, E., Yamanushi, T. T., Mahadevan, V. S., Gurney, A., White, E., Zhang, H. & Hart, G. & 2 others, Boyett, M. & Dobrzynski, H., 15 Dec 2016, In: Circulation: Arrhythmia and Electrophysiology. 9, e003432.

Research output: Contribution to journal › Article › peer-review

Open Access

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319 Downloads (Pure)

Calcium Extrusion Pump PMCA4: A New Player in Renal Calcium Handling?

van Loon, E. P. M., Little, R., Prehar, S., Bindels, R. J. M., Cartwright, E. J. & Hoenderop, J. G. J., 21 Apr 2016, In: PLoS ONE. 11, 4, e0153483.

Research output: Contribution to journal › Article › peer-review

Open Access

Circulating histone concentrations differentially affect the predominance of left or right ventricular dysfunction in critical illness.

Alhamdi, Y., Zi, M., Abrams, S. T., Liu, T., Su, D., Welters, I., Dutt, T., Cartwright, E. J., Wang, G. & Toh, C.-H., 1 May 2016, In: Critical Care Medicine. 44, 5, p. e278-e288

Research output: Contribution to journal › Article › peer-review

Open Access

File

200 Downloads (Pure)

The Plasma Membrane Calcium ATPase 4 Signalling in Cardiac Fibroblasts Mediates Cardiomyocyte Hypertrophy

Mohamed, T. M. A., Abou-Leisa, R., Stafford, N., Maqsood, A., Zi, M., Prehar, S., Baudoin, F., Wang, X., Neyses, L., Cartwright, E. & Oceandy, D., 29 Mar 2016, In: Nature Communications. 7:1107, 11074.

Research output: Contribution to journal › Article › peer-review

Open Access

Upregulation of mitofusin-2-friend or foe to the diabetic heart?

Murfitt, L., Iqbal, M. M., Bennett, H., Davenport, B., Pinali, C., Cooper, G. J., Cartwright, E. & Kitmitto, A., 2016.

Research output: Contribution to conference › Poster › peer-review

2015

Adverse remodelling of the cardiac conduction system (CCS) in heart failure could be the result of up and down regulation of microRNAs

Yanni Gerges, J., Zeef, L., Zi, M., Cai, X., Logantha, S., Li, J., Cartwright, E., Dobrzynski, H., Hart, G. & Boyett, M., 2015.

Research output: Contribution to conference › Abstract

Deletion of the intestinal plasma membrane calcium pump, isoform 1, Atp2b1, in mice is associated with decreased bone mineral density and impaired eesponsiveness to 1, 25-Dihydroxyvitamin D3.

Ryan, Z. C., Craig, T. A., Filoteo, A. G., Westendorf, J. J., Cartwright, E. J., Neyses, L., Strehler, E. E. & Kumar, R., 2015, In: Biochemical and biophysical research communications. 467, 1, p. 152–156

Research output: Contribution to journal › Article › peer-review

microRNA 370-3p could explain the dysfunction of the cardiac conduction system in heart failure

Yanni Gerges, J., Zi, M., Choudhury, M., Cai, X., Logantha, S., Li, J., Cartwright, E., Dobrzynski, H., Hart, G. & Boyett, M., 2015.

Research output: Contribution to conference › Abstract › peer-review

Open Access

Overexpression of mitofusin 2 in the diabetic heart; pathological or cardioprotective remodelling?

Murfitt, L., Iqbal, M. M., Pinali, C., Bennett, H., Cooper, G. J., Cartwright, E. & Kitmitto, A., 2015, p. s27-s28. 2 p.

Research output: Contribution to conference › Poster › peer-review

Open Access

Elizabeth Cartwright

Research output

Search results