Research output per year
Research output per year
- 1 - 50 out of 227 results
Search results
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2024
A comparison of the carbon footprint of alternative sampling approaches for cervical screening in the UK: a descriptive study
Whittaker, M., Davies, J. C., Sargent, A., Sawyer, M. & Crosbie, E., 1 Apr 2024, In: BJOG. 131, 5, p. 699-708Research output: Contribution to journal › Article › peer-review
Open Access -
Detection of endometrial cancer in cervico-vaginal fluid and blood plasma: Leveraging proteomics and machine learning for biomarker discovery.
Njoku, K., Pierce, A., Chiasserini, D., Geary, B., Campbell, A. E., Kelsall, J., Reed, R., Geifman, N., Whetton, A. D. & Crosbie, E. J., 1 Apr 2024, In: EBioMedicine. 105064.Research output: Contribution to journal › Article › peer-review
Open Access -
Extended panel testing in ovarian cancer reveals BRIP1 as the third most important predisposition gene
Morgan, R., Burghel, G., Flaum, N., Schlecht, H., Clamp, A., Hasan, J., Mitchell, C., Salih, Z., Moon, S., Hogg, M., Lord, R., Forde, C., Lalloo, F., Woodward, E., Crosbie, E., Taylor, S., Jayson, G. & Evans, D. G., 1 Oct 2024, In: Genetics in Medicine. 26, 10, 101230.Research output: Contribution to journal › Article › peer-review
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Factors associated with cervical screening coverage: a longitudinal analysis of English general practices from 2013 to 2022
Urwin, S., Gillibrand, S., Davies-Oliveira, J. & Crosbie, E., 1 Mar 2024, In: Journal of Public Health. 46, 1, p. e43–e50Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Clinical trials in cancer screening, prevention and early diagnosis (SPED): A systematic mapping review
Merriel, S., O'Dowd, E., Cheng, V. W., Khan, S., Howells, L., Gopal, D., Roundhill, E., Brennan, P., Crosbie, P., Neal, R. D., Brown, K., Crosbie, E. & Baldwin, D., 4 Sept 2023, In: BMC Cancer. 23, 1, 820.Research output: Contribution to journal › Article › peer-review
Open Access -
Evaluating multi-cancer early detection tests: an argument for the outcome of recurrence-updated stage
Callister, M. E. J., Crosbie, E. J., Crosbie, P. A. J. & Robbins, H. A., 12 Oct 2023, In: British Journal of Cancer. 129, 8, p. 1209-1211 3 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Incident cardiovascular events and imaging phenotypes in UK Biobank participants with past cancer
Estabragh, Z. R., Cooper , J., McCracken , C., Crosbie, E. J., Walter, F. M., Manisty , C. H., Robson, J., Mamas, M. A., Harvey, N. C., Neubauer, S. & Petersen, S. E., 18 Apr 2023, In: Heart. 109, 13, p. 1007-1015Research output: Contribution to journal › Article › peer-review
Open Access -
Is reflex germline BRCA1/2 testing necessary in women diagnosed with non-mucinous high-grade epithelial ovarian cancer aged 80 years or older?
Burghel, G., Flaum, N., Bulman, M., Smith, P., Clamp, A. R., Hasan, J., Mitchell, C. L., Salih, Z., Woodward, E. R., Lalloo, F., Crosbie, E., Edmondson, R., Schlecht, H., Jayson, G. C. & Evans, G., 1 Feb 2023, In: Cancers. 15, 3, 730.Research output: Contribution to journal › Article › peer-review
Open Access -
Lay and general practitioner attitudes towards endometrial cancer prevention: a cross-sectional study.
Kitson, S., Khan, U. & Crosbie, E., 28 Jul 2023, In: Family practice.Research output: Contribution to journal › Article › peer-review
Open Access -
Long-term risks of invasive cervical cancer following HPV infection: follow-up of two screening cohorts in Manchester
Gilham, C., Sargent, A., Crosbie, E. J. & Peto, J., 23 Mar 2023, In: British Journal of Cancer.. 128, p. 1933–1940Research output: Contribution to journal › Article › peer-review
Open Access -
Optimization of polygenic risk scores in BRCA1/2 pathogenic variant heterozygotes in epithelial ovarian cancer
Flaum, N., Bowes, J., Smith, M. J., Crosbie, E. J., Edmondson, R., Lophatananon, A. & Evans, D. G., 1 Sept 2023, In: Genetics in Medicine. 25, 9, 100898.Research output: Contribution to journal › Article › peer-review
Open Access -
Predicting risk of endometrial cancer in asymptomatic women (PRECISION): Model development and external validation
Kitson, S. J., Crosbie, E. J., Evans, D. G., Lophatananon, A., Muir, K. R., Ashcroft, D., Kontopantelis, E. & Martin, G. P., 10 Dec 2023, (E-pub ahead of print) In: BJOG : an international journal of obstetrics and gynaecology.Research output: Contribution to journal › Article › peer-review
Open Access -
Predicting the likelihood of a BRCA1/2 pathogenic variant being somatic by testing only tumour DNA in non-mucinous high-grade epithelial ovarian cancer
Morgan, R. D., Burghel, G. J., Flaum, N., Bulman, M., Smith, P., Clamp, A. R., Hasan, J., Mitchell, C., Salih, Z., Woodward, E. R., Lalloo, F., Shaw, J., Desai, S., Crosbie, E. J., Edmondson, R. J., Schlecht, H., Wallace, A. J., Jayson, G. C. & Evans, D. G. R., 1 Oct 2023, In: Journal Of Clinical Pathology. 76, 10, p. 684-689 6 p., jcp-2022-208369.Research output: Contribution to journal › Article › peer-review
Open AccessFile74 Downloads (Pure) -
Prognostic refinement of NSMP high-risk endometrial cancers using oestrogen receptor immunohistochemistry
Vermij, L., Jobsen, J. J., León-Castillo, A., Brinkhuis, M., Roothaan, S., Powell, M. E., De boer, S. M., Khaw, P., Mileshkin, L. R., Fyles, A., Leary, A., Genestie, C., Jürgenliemk-Schulz, I. M., Crosbie, E. J., Mackay, H. J., Nijman, H. W., Nout, R. A., Smit, V. T. H. B. M., Creutzberg, C. L. & Horeweg, N. & 2 others, , 23 Jan 2023, In: British Journal of Cancer.Research output: Contribution to journal › Article › peer-review
Open Access -
Quantitative SWATH-based proteomic profiling of urine for the identification of endometrial cancer biomarkers in symptomatic women
Njoku, K., Pierce, A., Geary, B., Campbell, A. E., Kelsall, J., Reed, R., Armit, A., Da sylva, R., Zhang, L., Agnew, H., Baricevic-Jones, I., Chiasserini, D., Whetton, A. D. & Crosbie, E. J., 17 Feb 2023, (E-pub ahead of print) In: British Journal of Cancer.Research output: Contribution to journal › Article › peer-review
Open Access -
Serum HE4 predicts progestin treatment response in endometrial cancer and atypical hyperplasia: A Prognostic study
Barr, C., Sergeant, J., Agnew, H., Bolton, J., McVey, R. J. & Crosbie, E., 1 Jul 2023, In: British Journal of Obstetrics and Gyanecology. 130, 8, p. 941-948Research output: Contribution to journal › Article › peer-review
Open Access -
Urine CA125 and HE4 for the Detection of Ovarian Cancer in Symptomatic Women
Barr, C. E., Njoku, K., Owens, G. L. & Crosbie, E. J., 16 Feb 2023, In: Cancers. 15, 4, 1256.Research output: Contribution to journal › Article › peer-review
Open Access -
Validation of lung cancer polygenic risk scores in a high-risk case-control cohort
Lebrett, M., Smith, M., Crosbie, E., Bowes, J., Byers, H., Evans, D. G. & Crosbie, P., 1 Aug 2023, In: Genetics in Medicine. 25, 8, 100882.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
A simple cervico-vaginal epigenetic test for screening and rapid triage of women with suspected endometrial cancer – validation in several cohort and case/control sets
Crosbie, E. J. & et al., 1 Jul 2022, (Accepted/In press) In: Journal of Clinical Oncology.Research output: Contribution to journal › Article › peer-review
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BRCA1/2 in non-mucinous epithelial ovarian cancer: tumour with or without germline testing?
Morgan, R. D., Burghel, G. J., Flaum , N., Bulman, M., Smith, P., Clamp, A. R., Hasan, J., Mitchell, C. L., Salih, Z., Woodward, E. R., Lalloo, F., Crosbie, E. J., Edmondson, R. J., Wallace, A. J., Jayson, G. C. & Evans, D. G. R., 22 Feb 2022, (Accepted/In press) In: BJC.Research output: Contribution to journal › Article › peer-review
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Cervical Screening – The Evolving Landscape
Davies-Oliveira, J. & Crosbie, E., 11 Jul 2022, (Accepted/In press) In: British Journal of General Practice.Research output: Contribution to journal › Article › peer-review
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Child and adult adiposity and subtype-specific endometrial cancer risk: a multivariable Mendelian randomisation study
Kennedy, O. J., Bafligil, C., O’mara, T. A., Wang, X., Evans, D. G., Kar, S. & Crosbie, E. J., 10 Nov 2022, (E-pub ahead of print) In: International journal of obesity.Research output: Contribution to journal › Article › peer-review
Open Access -
Current and emerging prognostic biomarkers in endometrial cancer
Njoku, K., Barr, C. & Crosbie, E., 28 Mar 2022, (Accepted/In press) In: Frontiers in Oncology.Research output: Contribution to journal › Review article › peer-review
Open Access -
Development and evaluation of polygenic risk scores for prediction of endometrial cancer risk in European women
Bafligil, C., Thompson, D. J., Lophatananon, A., Ryan, N., Smith, M. J., Dennis, J., Mekli, K., O'Mara, T. A., Evans, D. G. & Crosbie, E., 24 May 2022, (Accepted/In press) In: Genetics in Medicine.Research output: Contribution to journal › Article › peer-review
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Discordant prognosis of mismatch repair deficiency in colorectal and endometrial cancer reflects variation in antitumour immune response and immune escape
Glaire, M. A., Ryan, N. A., Ijsselsteijn, M. E., Kedzierska, K., Obolenski, S., Ali, R., Crosbie, E., Bosse, T., De Miranda, N. F. & Church, D. N., 9 Mar 2022, (E-pub ahead of print) In: The Journal of pathology.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Downloads (Pure) -
Dominant-negative pathogenic variant BRIP1 c.1045G>C is a high-risk allele for non-mucinous epithelial ovarian cancer: a case-control study
Flaum , N., van Veen, E. M., Smith, O., Amico, S., Newman, W., Crosbie, E., Edmondson, R., Smith, M. J. & Evans, D. G., 1 Jan 2022, In: Clin Genet. 101, 1, p. 48-54 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Explaining differences in the frequency of lung cancer detection between the National Lung Screening Trial and community-based screening in Manchester, UK
Robbins, H. A., Zahed, H., Lebrett, M. B., Balata, H., Johansson, M., Sharman, A., Evans, D. G., Crosbie, E. J., Booton, R., Landy, R. & Crosbie, P. A. J., 1 Sept 2022, In: Lung Cancer.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Downloads (Pure) -
Impact of pre-treatment prognostic nutritional index and the haemoglobin, albumin, lymphocyte and platelet (HALP) score on endometrial cancer survival: a prospective database analysis
Njoku, K., Barr, C., Ramchander, N. C. & Crosbie, E., 25 Jul 2022, (Accepted/In press) In: PLoS One..Research output: Contribution to journal › Article › peer-review
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Impact of Type 2 Diabetes Mellitus on Endometrial Cancer Survival: A Prospective Database Analysis
Njoku, K., Agnew, H. & Crosbie, E., 14 Apr 2022, (Accepted/In press) In: Frontiers in Oncology.Research output: Contribution to journal › Article › peer-review
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Infrared Spectroscopy of Urine for the Non-Invasive Detection of Endometrial Cancer
Meza ramirez, C., Stringfellow, H., Naik, R., Crosbie, E., Paraskevaidi, M., Rehman, I. & Martin-Hirsch, P., 13 Oct 2022, In: Cancers. 14, 20, p. 5015Research output: Contribution to journal › Article › peer-review
Open AccessFile56 Downloads (Pure) -
MSH2 is the very young onset ovarian cancer predisposition gene, not BRCA1
Flaum, N., Crosbie, E., Woodward, E., Lalloo, F., Morgan, R. D., Ryan , N. A. J. & Evans, D. G., 22 Dec 2022, (Accepted/In press) In: Journal of Medical Genetics.Research output: Contribution to journal › Letter › peer-review
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Quantifying the Effect of Physical Activity on Endometrial Cancer Risk
Kitson, S. J., Aurangzeb, O., Parvaiz, J., Lophatananon, A., Muir, K. & Crosbie, E. J., 13 Jun 2022, In: Cancer Prevention Research.Research output: Contribution to journal › Article › peer-review
Open AccessFile61 Downloads (Pure) -
Risk perception and disease knowledge in attendees of a community-based lung cancer screening programme
Lebrett, M. B., Crosbie, E. J., Yorke, J., Hewitt, K., Rowlands, A., Badrick, E., Evans, D. G., Balata, H., Booton, R. & Crosbie, P. A. J., 6 Apr 2022, In: Lung Cancer.Research output: Contribution to journal › Article › peer-review
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Serum CA125 and HE4 as Biomarkers for the Detection of Endometrial Cancer and Associated High-Risk Features
Barr, C. E., Njoku, K., Jones, E. R. & Crosbie, E. J., 17 Nov 2022, In: Diagnostics. 12, 11, p. 2834Research output: Contribution to journal › Article › peer-review
Open AccessFile61 Downloads (Pure) -
Synchronous uterine and bladder cancers detected in urine and vaginal samples by cytology
Narine, N., Rana, D., Shelton, D., Awad, D., O'Flynn, H., Jones, E., Ryan , N. A. J. & Crosbie, E., 1 Mar 2022, In: Diagnostic Cytopathology. 50, 3, p. E86-E91Research output: Contribution to journal › Article › peer-review
Open Access -
The performance of HE4 alone and in combination with CA125 for the detection of ovarian cancer in an enriched primary care population
Barr, C. E., Funston, G., Jeevan, D., Sundar, S., Mounce, L. T. A. & Crosbie, E. J., 19 Apr 2022, (Accepted/In press) In: Cancers.Research output: Contribution to journal › Article › peer-review
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Uptake and efficacy of bilateral risk reducing surgery in unaffected female BRCA1 and BRCA2 carriers
Marcinkute, R., Woodward, E., Gandhi, A., Howell, S., Crosbie, E., Wisely, J., Harvey, J., Highton, L., Murphy, J., Holland, C., Edmondson, R., Clayton, R. D., Barr, L., Harkness, E., Howell, T., Lalloo, F. & Evans, D. G., 1 Feb 2022, In: Journal of Medical Genetics. 59, 2, p. 133-140 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile150 Downloads (Pure) -
Urinary biomarkers for the detection of ovarian cancer: A systematic review
Owens, G., Barr, C., White, H., Njoku, K. & Crosbie, E., 13 May 2022, In: Carcinogenesis. 43, 4, 311–320.Research output: Contribution to journal › Article › peer-review
Open Access -
Urine CA125 and HE4 for the Triage of Symptomatic Women with Suspected Endometrial Cancer
Njoku, K., Barr, C., Sutton, C. J. J. & Crosbie, E., 6 Jul 2022, In: Cancers. 14, 14, 3306.Research output: Contribution to journal › Article › peer-review
Open Access -
Women’s Risk Perceptions and Willingness to Engage in Risk-Reducing Interventions for the Prevention of Obesity-Related Endometrial Cancer
Derbyshire, A. E., MacKintosh, M. L., Pritchard, C. M., Pontula, A., Ammori, B. J., Syed, A. A., Beeken, R. J. & Crosbie, E. J., 28 Jan 2022, In: International Journal of Women's Health.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Advances in genetic technologies result in improved diagnosis of mismatch repair deficiency in colorectal and endometrial cancers
Evans, D. G., Lalloo, F., Ryan, N. A., Bowers, N., Green, K., Woodward, E. R., Clancy, T., Bolton, J., McVey, R. J., Wallace, A. J., Newton, K., Hill, J., McMahon, R. & Crosbie, E. J., 15 Jan 2021, In: Journal of Medical Genetics.Research output: Contribution to journal › Article › peer-review
Open Access -
Comparison of Two Immunoassays for the Measurement of Serum HE4 for Ovarian Cancer
Barr, C., Funston, G., Mounce, L. T. A., Pemberton, P. W., Howe, J. D. & Crosbie, E., 26 Apr 2021, (Accepted/In press) In: Practical Laboratory Medicine.Research output: Contribution to journal › Article › peer-review
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Comprehensive library generation for identification and quantification of endometrial cancer protein biomarkers in cervico-vaginal fluid
Njoku, K., Chiasserini, D., Geary, B., Pierce, A., Jones, E. R., Whetton, A. & Crosbie, E., 23 Jul 2021, In: Cancers.Research output: Contribution to journal › Article › peer-review
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Could Ovarian Cancer Prediction Models Improve the Triage of Symptomatic Women in Primary Care? A Modelling Study Using Routinely Collected Data
Funston, G., Abel, G., Crosbie, E. J., Hamilton, W. & Walter, F. M., 9 Jun 2021, In: Cancers. 13, 12, 2886.Research output: Contribution to journal › Article › peer-review
Open Access -
Cytology for the diagnosis of endometrial cancer in symptomatic women
O'Flynn, H., Jones, E., Njoku, K., Rana, D., Shelton, D., Narine, N., Ramchander, N. C., Patel, V., Walter, F. M., Walsh, T. & Crosbie, E. J., 6 May 2021, In: Cochrane Database of Systematic Reviews. 2021, 5, CD014560.Research output: Contribution to journal › Review article › peer-review
Open AccessFile106 Downloads (Pure) -
Detecting Endometrial Cancer
Jones, E., O'Flynn, H., Njoku, K. & Crosbie, E., 19 Jan 2021, In: The Obstetrician and Gynaecologist.Research output: Contribution to journal › Article › peer-review
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DEveloping Tests for Endometrial Cancer deTection (DETECT): Protocol for a diagnostic accuracy study of urine and vaginal samples for the detection of endometrial cancer by cytology in women with postmenopausal bleeding
Jones, E., Carter, S., O'Flynn, H., Njoku, K., Barr, C., Narine, N., Shelton, D., Rana, D. & Crosbie, E., 5 Jul 2021, (Accepted/In press) In: BMJ Open.Research output: Contribution to journal › Article › peer-review
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Diagnostic accuracy of cytology for the detection of endometrial cancer in urine and vaginal samples
O'Flynn, H., Ryan, N., Narine, N., Shelton, D., Rana, D. & Crosbie, E., 11 Feb 2021, In: Nature Communications. 12, 952.Research output: Contribution to journal › Article › peer-review
Open Access1 Downloads (Pure) -
Does Clinical and Biochemical Thyroid Dysfunction Impact on Endometrial Cancer Survival Outcomes? A Prospective Database Study
Barr, C. E., Njoku, K., Hotchkies, L., Ryan, N. A. J., Wan, Y. L., Davies, D. A., Razvi, S. & Crosbie, E., 29 Oct 2021, In: Cancers.Research output: Contribution to journal › Article › peer-review
Open Access -
Eliminating cervical cancer: progress and challenges for high income countries
Davies-Oliveira, J., Smith, M. A., Grover, S., Canfell, K. & Crosbie, E., 24 Jul 2021, In: Clinical Oncology.Research output: Contribution to journal › Article › peer-review
Open AccessFile197 Downloads (Pure)