Harry Pritchard

2023

Acute, pro‐contractile effects of prorenin on rat mesenteric arteries

Rognant, S., Baldwin, S. N., Pritchard, H. A. T., Greenstein, A., Calloe, K., Aalkjaer, C. & Jepps, T. A., 1 Dec 2023, In: The FASEB Journal. 37, 12, e23282.

Research output: Contribution to journal › Article › peer-review

Open Access

A Multi-disciplinary Commentary on Preclinical Research to investigate Vascular Contributions to Dementia

Sri, S., Greenstein, A., Granata, A., Collcutt, A., Jochems, A. C. C., Mccoll, B. W., Castro, B. D., Webber, C., Reyes, C. A., Hall, C., Lawrence, C., Hawkes, C., Pegasiou-Davies, C.-M., Gibson, C., Crawford, C. L., Smith, C., Vivien, D., Mclean, F. H., Wiseman, F. & Brezzo, G. & 37 others, Lalli, G., Pritchard, H., Markus, H. S., Bravo-Ferrer, I., Taylor, J., Leiper, J., Berwick, J., Gan, J., Gallacher, J., Moss, J., Goense, J., Mcmullan, L., Work, L., Evans, L., Stringer, M. S., Ashford, M., Abulfadl, M., Conlon, N., Malhotra, P., Bath, P., Canter, R., Brown, R., Ince, S., Anderle, S., Young, S., Quick, S., Szymkowiak, S., Hill, S., Allan, S., Wang, T., Quinn, T., Procter, T., Farr, T. D., Zhao, X., Yang, Z., Hainsworth, A. H. & Wardlaw, J. M., 30 Oct 2023, In: Cerebral Circulation - Cognition and Behavior. 5, 100189.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Downloads (Pure)

Uncoupling of Ca 2+ sparks from BK channels in cerebral arteries underlies hypoperfusion in hypertension-induced vascular dementia.

Taylor, J. L., Walsh, K. R., Mosneag, I.-E., Danby, T. G. E., Luka, N., Chanda, B., Schiessl, I., Dunne, R. A., Hill-Eubanks, D., Hennig, G. W., Allan, S. M., Nelson, M. T., Greenstein, A. S. & Pritchard, H. A. T., 15 Aug 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 33, e2307513120.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Functionally linked potassium channel activity in cerebral endothelial and smooth muscle cells is compromised in Alzheimer's disease

Taylor, J. L., Pritchard, H. A. T., Walsh, K. R., Strangward, P., White, C., Hill-Eubanks, D., Alakrawi, M., Hennig, G. W., Allan, S. M., Nelson, M. T. & Greenstein, A. S., 28 Jun 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 26, p. e2204581119

Research output: Contribution to journal › Article › peer-review

2021

Brain Endothelial Cell TRPA1 Channels Initiate Neurovascular Coupling

Thakore, P., Alvarado, M. G., Ali, S., Mughal, A., Pires, P. W., Yamasaki, E., Pritchard, H. A. T., Isakson, B. E., Tran, C. H. T. & Earley, S., 26 Feb 2021

Research output: Other contribution › peer-review

Cardiovascular co-morbidities, inflammation and cerebral small vessel disease

Evans, L., Taylor, J., Smith, C., Pritchard, H., Greenstein, A. & Allan, S., 2021, In: Cardiovascular research.

Research output: Contribution to journal › Article › peer-review

Kynurenine Relaxes Arteries of Normotensive Women and Those with Preeclampsia

Worton, S. A., Pritchard, H. A., Greenwood, S. L., Alakrawi, M., Heazell, A. E., Wareing, M., Greenstein, A. S. & Myers, J. E., 3 Mar 2021, In: Circulation research.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

TRPML1 channels initiate Ca2+ sparks in vascular smooth muscle cells

Thakore, P., Pritchard, H. A. T., Griffin, C. S., Yamasaki, E., Drumm, B. T., Lane, C., Sanders, K. M., Feng Earley, Y. & Earley, S., 23 Jun 2020, In: Science Signaling. 13, 637

Research output: Contribution to journal › Article › peer-review

‘A Step and a Ceiling’: Mechanical properties of Ca2+ spark vasoregulation in resistance arteries by pressure-induced oxidative activation of PKG

Csato, V., Syed Abdul Kadir, S. Z., Khavandi, K., Bennett, H., Sugden, S., Gurney, A., Pritchard, H., Hill-Eubanks, D., Eaton, P., Nelson, M. & Greenstein, A., 2020, In: Physiological Reports. 7, 22, p. 1-12 12 p., e14260.

Research output: Contribution to journal › Article › peer-review

Open Access

2019

Nanoscale coupling of junctophilin-2 and ryanodine receptors regulates vascular smooth muscle cell contractility

Pritchard, H. A. T., Griffin, C. S., Yamasaki, E., Thakore, P., Lane, C., Greenstein, A. S. & Earley, S., 22 Oct 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 43, p. 21874-21881 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2018

Approaches for Investigating the Functional Significance of Transient Receptor Potential Cation Channels in Smooth Muscle Cells

Pritchard, H. T., Pires, P. W. & Earley, S., 6 Aug 2018, Signal Transduction and Smooth Muscle. Trebak, M. & Earley, S. (eds.). 1st ed. Boca Raton: CRC Press, p. 155-172 18 p. (Methods in Signal Transduction Series).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy

Pritchard, H. A. T., Pires, P. W., Yamasaki, E., Thakore, P. & Earley, S., 9 Oct 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 41, p. E9745-E9752

Research output: Contribution to journal › Article › peer-review

Open Access

2017

Microtubule structures underlying the sarcoplasmic reticulum support peripheral coupling sites to regulate smooth muscle contractility

Pritchard, H. A. T., Gonzales, A. L., Pires, P. W., Drumm, B. T., Ko, E. A., Sanders, K. M., Hennig, G. W. & Earley, S., 19 Sept 2017, In: Science Signaling. 10, 497

Research output: Contribution to journal › Article › peer-review

Open Access

The angiotensin II receptor type 1b is the primary sensor of intraluminal pressure in cerebral artery smooth muscle cells

Pires, P. W., Ko, E.-A., Pritchard, H. A. T., Rudokas, M., Yamasaki, E. & Earley, S., 15 Jul 2017, In: The Journal of physiology. 595, 14, p. 4735-4753 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2015

Molecular and functional significance of Ca(2+)-activated Cl(-) channels in pulmonary arterial smooth muscle

Leblanc, N., Forrest, A. S., Ayon, R. J., Wiwchar, M., Angermann, J. E., Pritchard, H. A. T., Singer, C. A., Valencik, M. L., Britton, F. & Greenwood, I. A., 1 Jun 2015, In: Pulmonary Circulation. 5, 2, p. 244-268 25 p.

Research output: Contribution to journal › Review article › peer-review

Unitary TRPV3 channel Ca2+ influx events elicit endothelium-dependent dilation of cerebral parenchymal arterioles

Pires, P. W., Sullivan, M. N., Pritchard, H. A. T., Robinson, J. J. & Earley, S., 15 Dec 2015, In: American Journal of Physiology: Heart and Circulatory Physiology. 309, 12, p. H2031-H2041 11 p.

Research output: Contribution to journal › Article › peer-review

2014

Inhibitory role of phosphatidylinositol 4,5-bisphosphate on TMEM16A-encoded calcium-activated chloride channels in rat pulmonary artery

Pritchard, H. A. T., Leblanc, N., Albert, A. P. & Greenwood, I. A., Sept 2014, In: British Journal of Pharmacology. 171, 18, p. 4311-21 11 p.

Research output: Contribution to journal › Article › peer-review

2012

Potent vasorelaxant activity of the TMEM16A inhibitor T16Ainh‐A01

Davis, A. J., Shi, J., Pritchard, H. A., Chadha, P. S., Leblanc, N., Vasilikostas, G., Yao, Z., Verkman, A., Albert, A. P. & Greenwood, I. A., Sept 2012, In: British Journal of Pharmacology. 168, 3, p. 773-784 12 p.

Research output: Contribution to journal › Article › peer-review

Harry Pritchard

Research output

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