Research output per year
Research output per year
- 12 results
Search results
-
2023
Overexpression of IκB⍺ modulates NF-κB activation of inflammatory target gene expression
Downton, P., Bagnall, J. S., England, H., Spiller, D. G., Humphreys, N. E., Jackson, D. A., Paszek, P., White, M. R. H. & Adamson, A. D., 9 May 2023, (E-pub ahead of print) In: Frontiers in Molecular Biosciences. 10, 1187187.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Effects of Human RelA Transgene on Murine Macrophage Inflammatory Responses
Papoutsopoulou, S., Morris, L., Bayliff, A., Mair, T., England, H., Stagi, M., Bergey, F., Alam, M. T., Tezerji, R. S., Rosenstiel, P., Muller, W., santos, V. M. D. & Campbell, B., 24 Mar 2022, In: Biomedicines. 10, 4, 757.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Gene-Specific Linear Trends Constrain Transcriptional Variability of the Toll-like Receptor Signaling
Bagnall, J., Rowe, W., Alachkar, N., Roberts, J., England, H., Clark, C., Platt, M., Jackson, D., Muldoon, M. & Paszek, P., 23 Sept 2020, In: Cell Systems. 11, 3, p. 300-314.e8Research output: Contribution to journal › Article › peer-review
Open Access -
Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease
SysmedIBD consortium, Lloyd, K., Papoutsopoulou, S., Smith, E., Stegmaier, P., Bergey, F., Morris, L., Kittner, M., England, H., Spiller, D., White, M., Campbell, B. J., Duckworth, C. A., Poroikov, V., Martins dos Santos, V. A., Kel, A., Muller, W., Pritchard, D. M., Probert, C. & Burkitt, M. D., 21 Sept 2020, In: DMM Disease Models and Mechanisms.Research output: Contribution to journal › Article › peer-review
Open AccessFile206 Downloads (Pure) -
2019
Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients
Papoutsopoulou, S., Burkitt, M. D., Bergey, F., England, H., Rachel, H., Schmidt, L., Spiller, D., White, M., Paszek, P., Jackson, D., Martins Dos Santos, V. A. P., Selge, G., Prittchard, M. D., Campbell, B. J., Muller, W. & Probert, C. S., 11 Sept 2019, In: Frontiers in Immunology. 10, p. 2168Research output: Contribution to journal › Article › peer-review
Open Access -
2018
Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation
Bagnall, J., Boddington, C., England, H., Brignall, R., Downton, P., Alsoufi, Z., Boyd, J., Rowe, W., Bennett, A., Walker, C., Adamson, A., Patel, N., O'Cualain, R., Schmidt, L., Spiller, D., Jackson, D., Muller, W., Muldoon, M., White, M. & Paszek, P., 24 Jul 2018, In: Science Signaling. 11, 540, 15 p., eaaf3998.Research output: Contribution to journal › Article › peer-review
Open AccessFile168 Downloads (Pure) -
2017
Anti-inflammatory effects of infliximab in mice are independent of TNFα neutralization
Assas, B. M., Levison, S., Little, M., England, H., Battrick, L., Bagnall, J., Mclaughlin, J., Paszek, P., Else, K. & Pennock, J., Feb 2017, In: Clinical and experimental immunology. 187, 2Research output: Contribution to journal › Article › peer-review
Open Access -
Boron based inhibitors of the NLRP3 inflammasome
Baldwin, A., Rivers-Auty, J., Daniels, M., White, C., Schwalbe, C. H., Schilling, T., Hammadi, H., Jaiyong, P., Spencer, N. G., England, H., Luheshi, N. M., Kadirvel, M., Lawrence, C. B., Rothwell, N., Harte, M., Bryce, R., Allen, S., Eder, C., Freeman, S. & Brough, D., 16 Nov 2017, In: Cell Chemical Biology. 24, 11, p. 1321-1335 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Integration of kinase and calcium signaling at 1 the level of chromatin underlies inducible gene activation in T cells
Brignall, R., Cauchy, P., Bevington, S. L. B., Gorman, B., Pisco, A. O., Bagnall, J., Boddington, C., Rowe, W., England, H., Rich, K., Schmidt, L., Dyer, N. P., Travis, M., Ott, S., Jackson, D., Cockerill, P. N. & Paszek, P., 15 Oct 2017, In: Journal of Immunology. 199, 8, p. 2652-2667Research output: Contribution to journal › Article › peer-review
Open Access -
2015
A novel small molecule inhibitor of the NLRP3 inflammasome for the treatment of sterile inflammation
Baldwin, A., Rivers-Auty, J., England, H., Luheshi, N., Daniels, M., Allan, S., Brough, D. & Freeman, S., 9 Aug 2015.Research output: Contribution to conference › Poster
-
Boron-based small molecule inhibitors of the NLRP3 inflammasome for the treatment of sterile inflammation.
Baldwin, A., Rivers-Auty, J., England, H., Luheshi, N., Daniels, M., Allan, S., Brough, D. & Freeman, S., Oct 2015.Research output: Contribution to conference › Poster
-
2014
Release of interleukin-1 α or interleukin-1 β depends on mechanism of cell death
England, H., Summersgill, H., Edye, M., Rothwell, N. & Brough, D., 6 Jun 2014, In: Journal of Biological Chemistry. 289, 23, p. 15942-15950 9 p.Research output: Contribution to journal › Article › peer-review
Open Access