Personal profile
Overview
Professor of Rheumatology and Neuromuscular Disease, based in the Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences. Also Honorary Clinical Consultant at The Rheumatic Diseases Centre, Salford Royal NHS Foundation Trust. The academic component of my job is HEFCE funded and the clinical component funded by the trust, the split being 50:50.
My primary research interest is in the investigation of genetic and environmental risk factors in inflammatory muscle disease, or myositis. This is complemented via the Salford Royal Adult Neuromuscular Service, where patients are clinically managed within an NHS Specialised Rheumatology service and given the opportunity for recruitment into ongoing research studies.
Biography
Professor Hector Chinoy is a Professor of Rheumatology and Neuromuscular Disease at The University of Manchester, UK, where he conducts an active programme of research. He is Programme Director of the MSc in Clinical Rheumatology and Musculoskeletal Medicine. At Salford Royal NHS Foundation Trust, he is an Honorary Consultant Rheumatologist and part of the Neuromuscular team.
Professor Chinoy completed his medical degree at the University of Nottingham in 1996 and undertook an Arthritis Research UK PhD fellowship at The University of Manchester. He now has research interests in genetic, epidemiological and clinical aspects of adult idiopathic inflammatory myopathy, and supervises a number of PhD and Masters students. He is principal investigator of a UK Medical Research Council funded prospective myositis cohort collection called MYOPROSP. At Salford Royal, he runs general rheumatology, adult neuromuscular and combined psoriasis/psoriatic clinics.
He is a reviewer for several major rheumatology peer-reviewed journals, advisory editor for Arthritis and Rheumatology, on the editorial board for the European Medical Journal and Reumatologia, and is on the abstract selection committee for the British Society for Rheumatology, European League Against Rheumatism and American College of Rheumatology annual conferences.
He is co-chair of UKMYONET, a national consortium that fosters collaborative research in inflammatory myopathy, chair of the Euromyositis registry, a consortium that collects standardised clinical data in over 30 countries. He is also part of the Versus Arthritis Autoimmune rheumatic disease research advisory group.
Research interests
My current research interest is in the immunogenetics of idiopathic inflammatory myopathy (IIM).
Objectives:
- Further analysis of GWAS and Immunochip data generated from a UK-based and international cohort of IIM patients.
- To facilitate and oversee replication association studies of disease susceptibility signals from GWAS and pan-autoimmune loci
- To facilitate and oversee the identification of potential disease-causal variants within IIM susceptibility genes via genetic re-sequencing and high-throughput genotyping.
- Coordinating a prospective collection of IIM data in the UK (MYOPROSP)
- NHS England registry collection of IIM patients commencing rituximab (MYOACT)
- Novel imaging modalities in IIM
- Use of PROMS to measure disease activity in IIM
- Dissemination of Euromyositis, a European-wide standardised web-based IIM database facility (collaboration)
- To study subclinical atherosclerosis and endothelial dysfunction in IIM
- To facilitate collection of blood and tissue as part of a muscle biobank and UKMYONET, a nationwide UK Clinical Research Network IIM study
- To investigate the interaction of smoking and HLA-DRB1*03 for the development of myositis antibodies in IIM (collaboration)
- To assist in the clinical and genetic phenotypic characterisation of IIM cases with novel autoantibody profiles (collaboration)
- Management of idiopathic inflammatory myopathies: adult patients and professional specialists’ perspectives on current care in the UK (collaboration)
Teaching
A) University
Postgraduate Teaching
- MSc Clinical Rheumatology Programme, The University of Manchester
- Programme director (350 Teaching Load hours, ~ 1 PA/week)
- Teaching and examining role in the programme
- Supervision of students in written dissertation component (1 current, 3 previous).
Undergraduate Work
- Teaching: 4th year medical students as part of ward/ clinical-based sessions, expert patient sessions and formal rheumatology lectures (Hospital-based) (2009-present)
- Advisor: Phase II Academic Advisor (2015-present)
- Examiner: Lead and examiner for Mind and Movement OSCE examination Salford Royal (commitment 5 days per year) (Hospital-based) (2013-present)
- Supervisor: Year 3/4 APEP medical students
- Interviews: Manchester Medical School 2015 applicants, 15/12/2014, 15/01/2015
B) Other roles
- British Society for Rheumatology (BSR) representation - chair of the BSR myositis special interest group
- Arthritis Research UK Representative, Autoimmune Rheumatic Disease Clinical Trials Subcommittee (2012-present)
- NHS Specialist Commissioning: Co-drafting NHS England national policy for the use of rituximab in myositis (2014)
- Arthritis and Rheumatology, Advisory Editor, (11/2014-)
- Reviewer for multiple journals (eg ARD, Arthritis Rheum, Arthritis Care & Research, Rheumatology, Clin Exp Rheumatol)
- Joint lead of UKMYONET, a UK-wide research group to promote collaborative research in myositis
- Member, EuMyoNet & MYOGEN, international consortia collaborating in myositis research
- Chair, Euromyositis Registry, a web-based database consortium of over 20 countries
- Invited speaker for national and international conferences (examples ACR 2012, EULAR 2014, 1st National Chinese Myositis Conference,China-Japan Friendship Hospital, Beijing)
My collaborations
- Prof R.G.Cooper, Consultant Rheumatologist, Salford Royal NHS Foundation Trust
- Prof W.E.Ollier, Professor of Immunogenetics/Director, CIGMR
- Dr J.Lamb, Lecturer in Complex Human Genetics/Genomics, CIGMR
- Prof L.R.Wedderburn, Professor in Paediatric Rheumatology, Institute of Child Health, UCL, London
- Prof N.J.McHugh, Consultant Rheumatologist, RNHRD, Bath. Hon Professor University of Bath
Memberships of committees and professional bodies
- British Society for Rheumatology
- American College of Rheumatology
- General Medical Council
- British Medical Association
- Royal College of Physicians (London)
Qualifications
- 2007 PhD, Medicine (The University of Manchester)
- 2004 MSc, Clinical Rheumatology (The University of Manchester)
- 2000 MRCP (UK)
- 1996 B.M., B.S. (University of Nottingham)
- 1994 B.Med.Sci (Hons), 2nd class, division 1 (University of Nottingham)
Areas of expertise
- R Medicine (General)
- Rheumatology
- Myositis
- Muscle
- Antibodies
- Neuromuscular disease
- Psoriatic arthritis
- Myopathies
Research Beacons, Institutes and Platforms
- Digital Futures
- Lydia Becker Institute
Keywords
- Muscle
- Myositis
- Myopathies
- Psoriatic arthritis
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 4 Quality Education
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SDG 10 Reduced Inequalities
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Determinants of physical function, as measured using PROMIS PF-10a, in patients with rheumatoid arthritis: results from the international COVID-19 Vaccination in Autoimmune Diseases (COVAD) study
COVAD Study Group, Ali, S. S., Demetriou, C., Parodis, I., Tan, A. L., Edgar Gracia-Ramos, A., Joshi, M., Caballero-Uribe, C. V., Saha, S., Lilleker, J. B., Nune, A., Pauling, J. D., Wincup, C., Jagtap, K., Dey, D., Milchert, M., Distler, O., Chinoy, H., Agarwal, V. & Gupta, L. & 1 others, , 21 Jan 2025, In: Rheumatology Advances in Practice. 9, 1, rkae154.Research output: Contribution to journal › Article › peer-review
Open Access -
HLA Loci Heterozygosity Modulates Genetic Risk in Idiopathic Inflammatory Myopathies
Chen, G., Zhu, C., Chinoy, H., Amos, C. I., Lamb, J. A., Amos, C., Zhu, C., Benveniste, O., Chinoyv, H., Bleecker, J. L. D., Paepe, B. D., Doria, A., Geiger, Z., Gregersen, P. K., Hanna, M. G., Lamb, J. A., Limaye, V., Lundberg, I., Padyukov, L. & Machado, P. & 13 others, , 1 Oct 2025, In: Annals of the rheumatic diseases. 84, 10, p. 1696-1705Research output: Contribution to journal › Article › peer-review
Open Access -
Pretreatment absolute monocyte counts are associated with biological disease-modifying anti-rheumatic drug non-response in patients with rheumatoid arthritis
Ling, S. F., Ho, P., Bukhari, M., Mewar, D., Chinoy, H., Morgan, A. W., Isaacs, J. D., Wilson, A. G., Hyrich, K. L., Barton, A. & Plant, D., 21 May 2025, (E-pub ahead of print) In: Scandinavian Journal of Rheumatology. p. 1-6 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Replicating a COVID-19 study in a national England database to assess the generalisability of research with regional electronic health record data
CVDCOVID-UK/COVID-IMPACT Consortium, 23 Apr 2025, In: BMJ Open. 15, 4, e093080.Research output: Contribution to journal › Article › peer-review
Open Access -
Small molecules in idiopathic inflammatory myopathies: A systematic review and a multicentre case series about JAK inhibitors and Apremilast
Rizzo, C., Grazzini, S., Conticini, E., Chinoy, H., D’Alessandro, R., Camarda, F., Cantarini, L., Frediani, B., Guggino, G. & Barbera, L. L., 13 Jan 2025, In: Reumatismo.Research output: Contribution to journal › Article › peer-review
Open Access
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MMRG: Manchester Myositis Research Group
Chinoy, H. (PI), Lamb, J. (PI), Ollier, W. (PI), Rothwell, S. (CoI), Lilleker, J. (CoI), Oldroyd, A. (PGR student), Snedden, A. (PGR student), Platt, H. (Support team) & New, P. (Support team)
1/01/10 → …
Project: Research
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Centre for Musculoskeletal Research
Barton, A. (PI), Bluett, J. (PI), Bowes, J. (PI), Bruce, I. (PI), Buch, M. (PI), Chinoy, H. (PI), Eyre, S. (PI), Herrick, A. (PI), Hughes, M. (PI), Humphreys, J. H. (PI), Hyrich, K. (PI), Jani, M. (PI), Kearsley-Fleet, L. (PI), Lee, R. (PI), Lunt, M. (PI), Martin, P. (PI), Morris, A. (PI), Murray, A. (PI), O'Neill, T. (PI), Orozco, G. (PI), Plant, D. (PI), Shoop-Worrall, S. (PI), Verstappen, S. (PI) & Viatte, S. (PI)
Project: Research
Prizes
Activities
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Statin myopathy and myositis
Chinoy, H. (Speaker)
7 Jul 2022Activity: Talk or presentation › Invited talk › Research
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Management of Refractory Inflammatory Myopathy
Chinoy, H. (Speaker)
23 Jun 2022Activity: Talk or presentation › Invited talk › Research
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Treatment Management: Inflammatory Myopathies
Chinoy, H. (Speaker)
10 Jun 2022Activity: Talk or presentation › Invited talk › Research
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Update in the management of inflammatory myopathy
Chinoy, H. (Speaker)
19 May 2022Activity: Talk or presentation › Invited talk › Research
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BSR guideline on the management of paediatric, adolescent and adult patients with idiopathic inflammatory myopathy
Chinoy, H. (Speaker)
26 Apr 2022Activity: Talk or presentation › Invited talk › Research
Datasets
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Systematic protein-protein interaction and pathway analyses in the idiopathic inflammatory myopathies
Parkes, J. (Contributor), Rothwell, S. (Contributor), Day, P. (Contributor), McHugh, N. J. (Contributor), Betteridge, Z. E. (Contributor), Cooper, R. G. (Contributor), Ollier, W. (Contributor), Chinoy, H. (Contributor) & Lamb, J. (Contributor), figshare , 7 Jul 2016
DOI: 10.6084/m9.figshare.c.3609506.v1, https://figshare.com/collections/Systematic_protein-protein_interaction_and_pathway_analyses_in_the_idiopathic_inflammatory_myopathies/3609506/1
Dataset
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Patient-centred standards of care for adults with myositis
Lilleker, J. (Creator), Gordon, P. (Creator), Lamb, J. (Creator), Lempp, H. (Creator), Cooper, R. (Creator), Roberts, M. (Creator), Jordan, P. (Creator) & Chinoy, H. (Creator), figshare , 28 Nov 2017
DOI: 10.6084/m9.figshare.c.4041848
Dataset
Press/Media
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BSR Myositis Guideline
31/03/22 → 1/06/22
5 items of Media coverage, 2 Media contributions
Press/Media: Blogs and social media
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Retrospectively reviewing polymyositis diagnoses in a large single-centre cohort
15/02/21
1 Media contribution
Press/Media: Blogs and social media
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Global first for Salford team in rare disease study
4/12/19 → 9/01/20
3 items of Media coverage
Press/Media: Research
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Cancer risk associated with anti-TIF1 antibodies
Chinoy, H., Oldroyd, A. & Lamb, J.
7/01/19
1 Media contribution
Press/Media: Expert comment
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Anti-TIF1-Ab-Positive Dermatomyositis Linked to Higher Cancer Risk
15/12/18
1 item of Media coverage
Press/Media: Blogs and social media